| Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing BW Kunkle, B Grenier-Boley, R Sims, JC Bis, V Damotte, AC Naj, ... Nature genetics 51 (3), 414-430, 2019 | 2556 | 2019 |
| Chapter 11: Genome-wide association studies WS Bush, JH Moore PLoS computational biology 8 (12), e1002822, 2012 | 2019 | 2012 |
| New insights into the genetic etiology of Alzheimer’s disease and related dementias C Bellenguez, F Küçükali, IE Jansen, L Kleineidam, S Moreno-Grau, ... Nature genetics 54 (4), 412-436, 2022 | 1462 | 2022 |
| Large-scale association analysis identifies new lung cancer susceptibility loci and heterogeneity in genetic susceptibility across histological subtypes JD McKay, RJ Hung, Y Han, X Zong, R Carreras-Torres, DC Christiani, ... Nature genetics 49 (7), 1126-1132, 2017 | 620 | 2017 |
| A balanced accuracy function for epistasis modeling in imbalanced datasets using multifactor dimensionality reduction DR Velez, BC White, AA Motsinger, WS Bush, MD Ritchie, SM Williams, ... Genetic Epidemiology: the Official Publication of the International Genetic …, 2007 | 495 | 2007 |
| Trans-ancestry genome-wide association meta-analysis of prostate cancer identifies new susceptibility loci and informs genetic risk prediction DV Conti, BF Darst, LC Moss, EJ Saunders, X Sheng, A Chou, ... Nature genetics 53 (1), 65-75, 2021 | 391 | 2021 |
| The phenotypic legacy of admixture between modern humans and Neandertals CN Simonti, B Vernot, L Bastarache, E Bottinger, DS Carrell, RL Chisholm, ... Science 351 (6274), 737-741, 2016 | 377 | 2016 |
| Unravelling the human genome–phenome relationship using phenome-wide association studies WS Bush, MT Oetjens, DC Crawford Nature Reviews Genetics 17 (3), 129-145, 2016 | 307 | 2016 |
| Sex-specific association of apolipoprotein E with cerebrospinal fluid levels of tau TJ Hohman, L Dumitrescu, LL Barnes, M Thambisetty, G Beecham, ... JAMA neurology 75 (8), 989-998, 2018 | 268 | 2018 |
| Whole exome sequencing study identifies novel rare and common Alzheimer’s-Associated variants involved in immune response and transcriptional regulation JC Bis, X Jian, BW Kunkle, Y Chen, KL Hamilton-Nelson, WS Bush, ... Molecular psychiatry 25 (8), 1859-1875, 2020 | 263 | 2020 |
| Genetic variation among 82 pharmacogenes: the PGRNseq data from the eMERGE network WS Bush, DR Crosslin, A Owusu‐Obeng, J Wallace, B Almoguera, ... Clinical Pharmacology & Therapeutics 100 (2), 160-169, 2016 | 197 | 2016 |
| Association of arrhythmia-related genetic variants with phenotypes documented in electronic medical records SL Van Driest, QS Wells, S Stallings, WS Bush, A Gordon, DA Nickerson, ... Jama 315 (1), 47-57, 2016 | 192 | 2016 |
| Cystic fibrosis–related diabetes is caused by islet loss and inflammation NJ Hart, R Aramandla, G Poffenberger, C Fayolle, AH Thames, A Bautista, ... JCI insight 3 (8), 2018 | 180 | 2018 |
| The Alzheimer's Disease Sequencing Project: study design and sample selection GW Beecham, JC Bis, ER Martin, SH Choi, AL DeStefano, CM Van Duijn, ... Neurology: Genetics 3 (5), e194, 2017 | 160 | 2017 |
| Biofilter: a knowledge-integration system for the multi-locus analysis of genome-wide association studies WS Bush, SM Dudek, MD Ritchie Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing, 368, 2009 | 160 | 2009 |
| ICD-9 tobacco use codes are effective identifiers of smoking status LK Wiley, A Shah, H Xu, WS Bush Journal of the American Medical Informatics Association 20 (4), 652-658, 2013 | 148 | 2013 |
| The MafA transcription factor becomes essential to islet β-cells soon after birth Y Hang, T Yamamoto, RKP Benninger, M Brissova, M Guo, W Bush, ... Diabetes 63 (6), 1994-2005, 2014 | 147 | 2014 |
| Is isolated low high-density lipoprotein cholesterol a cardiovascular disease risk factor? New insights from the Framingham offspring study J Bartlett, IM Predazzi, SM Williams, WS Bush, Y Kim, S Havas, PP Toth, ... Circulation: Cardiovascular Quality and Outcomes 9 (3), 206-212, 2016 | 122* | 2016 |
| Genetic variants and functional pathways associated with resilience to Alzheimer’s disease L Dumitrescu, ER Mahoney, S Mukherjee, ML Lee, WS Bush, ... Brain 143 (8), 2561-2575, 2020 | 118 | 2020 |
| Human islet preparations distributed for research exhibit a variety of insulin-secretory profiles NS Kayton, G Poffenberger, J Henske, C Dai, C Thompson, R Aramandla, ... American Journal of Physiology-Endocrinology and Metabolism 308 (7), E592-E602, 2015 | 103 | 2015 |
