Christina A. Pacak, Ph.D.
Christina A. Pacak, Ph.D.
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Recombinant adeno-associated virus serotype 9 leads to preferential cardiac transduction in vivo
CA Pacak, CS Mah, BD Thattaliyath, TJ Conlon, MA Lewis, DE Cloutier, ...
Circulation research 99 (4), e3-e9, 2006
Genetic fate of recombinant adeno-associated virus vector genomes in muscle
BC Schnepp, KR Clark, DL Klemanski, CA Pacak, PR Johnson
Journal of virology 77 (6), 3495-3504, 2003
Transplantation of Autologously-Derived Mitochondria Protects the Heart from Ischemia-Reperfusion Injury
A Masuzawa, KM Black, CA Pacak, M Ericsson, RJ Barnett, C Drumm, ...
American Journal of Physiology-Heart and Circulatory Physiology, 2013
Pompe disease gene therapy
BJ Byrne, DJ Falk, CA Pacak, S Nayak, RW Herzog, ME Elder, SW Collins, ...
Human molecular genetics 20 (R1), R61-R68, 2011
Neonatal intraperitoneal or intravenous injections of recombinant adeno-associated virus type 8 transduce dorsal root ganglia and lower motor neurons
KD Foust, A Poirier, CA Pacak, RJ Mandel, TR Flotte
Human gene therapy 19 (1), 61-70, 2008
Tissue specific promoters improve specificity of AAV9 mediated transgene expression following intra-vascular gene delivery in neonatal mice
CA Pacak, Y Sakai, BD Thattaliyath, CS Mah, BJ Byrne
Genetic vaccines and therapy 6 (1), 13, 2008
Injection of isolated mitochondria during early reperfusion for cardioprotection
JD McCully, DB Cowan, CA Pacak, IK Toumpoulis, H Dayalan, S Levitsky
American Journal of Physiology-Heart and Circulatory Physiology 296 (1), H94 …, 2009
Physiological correction of Pompe disease by systemic delivery of adeno-associated virus serotype 1 vectors
C Mah, CA Pacak, KO Cresawn, LR DeRuisseau, S Germain, MA Lewis, ...
Molecular Therapy 15 (3), 501-507, 2007
Sustained correction of glycogen storage disease type II using adeno-associated virus serotype 1 vectors
C Mah, KO Cresawn, TJ Fraites, CA Pacak, MA Lewis, I Zolotukhin, ...
Gene Therapy 12 (18), 1405-1409, 2005
Actin-dependent mitochondrial internalization in cardiomyocytes: evidence for rescue of mitochondrial function
CA Pacak, JM Preble, H Kondo, P Seibel, S Levitsky, J Pedro, DB Cowan, ...
Biology open 4 (5), 622-626, 2015
AAV vectors for cardiac gene transfer: experimental tools and clinical opportunities
CA Pacak, BJ Byrne
Molecular Therapy 19 (9), 1582-1590, 2011
Long-term skeletal muscle protection after gene transfer in a mouse model of LGMD-2D
CA Pacak, GA Walter, G Gaidosh, N Bryant, MA Lewis, S Germain, ...
Molecular Therapy 15 (10), 1775-1781, 2007
Rapid isolation and purification of mitochondria for transplantation by tissue dissociation and differential filtration
JM Preble, CA Pacak, H Kondo, AA MacKay, DB Cowan, JD McCully
JoVE (Journal of Visualized Experiments), e51682, 2014
A targeted gain of function screen in the embryonic CNS of Drosophila
VL McGovern, CA Pacak, ST Sewell, ML Turski, MA Seeger
Mechanisms of development 120 (10), 1193-1207, 2003
Infiltrative and drug‐resistant slow‐cycling cells support metabolic heterogeneity in glioblastoma
LB Hoang‐Minh, FA Siebzehnrubl, C Yang, S Suzuki‐Hatano, K Dajac, ...
The EMBO journal 37 (23), e98772, 2018
AAV-Mediated TAZ Gene Replacement Restores Mitochondrial and Cardioskeletal Function in Barth Syndrome
S Suzuki-Hatano, M Saha, SA Rizzo, RL Witko, BJ Gosiker, ...
Human gene therapy 30 (2), 139-154, 2019
Ultrarapid purification of collagen type I for tissue engineering applications
CA Pacak, JM Powers, DB Cowan
Tissue Engineering Part C: Methods 17 (9), 879-885, 2011
Relative persistence of AAV serotype 1 vector genomes in dystrophic muscle
CA Pacak, T Conlon, CS Mah, BJ Byrne
Genetic Vaccines and Therapy 6 (1), 14, 2008
An improved method for the preparation of type I collagen from skin
CA Pacak, AA MacKay, DB Cowan
JoVE (Journal of Visualized Experiments), e51011, 2014
Impaired cardiac and skeletal muscle bioenergetics in children, adolescents, and young adults with Barth syndrome
A Bashir, KL Bohnert, DN Reeds, LR Peterson, AJ Bittel, ...
Physiological reports 5 (3), e13130, 2017
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