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Bryan Trevor SEWELL
Bryan Trevor SEWELL
Professor in the Division of Medical Biochemistry,niversity of Cape Town
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Detection of a SARS-CoV-2 variant of concern in South Africa
H Tegally, E Wilkinson, M Giovanetti, A Iranzadeh, V Fonseca, ...
Nature 592 (7854), 438-443, 2021
14692021
Emergence and rapid spread of a new severe acute respiratory syndrome-related coronavirus 2 (SARS-CoV-2) lineage with multiple spike mutations in South Africa
H Tegally, E Wilkinson, M Giovanetti, A Iranzadeh, V Fonseca, ...
medrxiv, 2020.12. 21.20248640, 2020
11972020
Fate of haem iron in the malaria parasite Plasmodium falciparum.
TJ Egan, JM Combrinck, J Egan, GR Hearne, HM Marques, S Ntenteni, ...
Biochemical Journal 365 (Pt 2), 343, 2002
3912002
Kosakovsky Pond SL, Weaver S, Martin D, Lessells RJ, Bhiman JN, Williamson C, de Oliveira T. Detection of a SARS-CoV-2 variant of concern in South Africa
H Tegally, E Wilkinson, M Giovanetti, A Iranzadeh, V Fonseca, ...
Nature 592 (7854), 438-443, 2021
2152021
Microbial nitrilases: versatile, spiral forming, industrial enzymes
RN Thuku, D Brady, MJ Benedik, BT Sewell
Journal of applied microbiology 106 (3), 703-727, 2009
1862009
Emergence of a SARS-CoV-2 variant of concern with mutations in spike glycoprotein
H Tegally, E Wilkinson, M Giovanetti, A Iranzadeh, V Fonseca, ...
Nature 592 (7854), 438-443, 2021
1472021
[23] Isolation and characterization of histones
C Von Holt, WF Brandt, HJ Greyling, GG Lindsey, JD Retief, JA Rodrigues, ...
Methods in enzymology 170, 431-523, 1989
1451989
X-ray analyses of aspartic proteinases: The three-dimensional structure at 2.1 Å resolution of endothiapepsin
TL Blundell, JA Jenkins, BT Sewell, LH Pearl, JB Cooper, IJ Tickle, ...
Journal of molecular biology 211 (4), 919-941, 1990
1381990
CynD, the Cyanide Dihydratase from Bacillus pumilus: Gene Cloning and Structural Studies
D Jandhyala, M Berman, PR Meyers, BT Sewell, RC Willson, MJ Benedik
Applied and Environmental Microbiology 69 (8), 4794-4805, 2003
1122003
The Structure of Testis Angiotensin-Converting Enzyme in Complex with the C Domain-Specific Inhibitor RXPA380,
HR Corradi, I Chitapi, BT Sewell, D Georgiadis, V Dive, ED Sturrock, ...
Biochemistry 46 (18), 5473-5478, 2007
1072007
Crystal structure of a thermostable old yellow enzyme from Thermus scotoductus SA-01
DJ Opperman, BT Sewell, D Litthauer, MN Isupov, JA Littlechild, ...
Biochemical and biophysical research communications 393 (3), 426-431, 2010
922010
Post‐translational cleavage of recombinantly expressed nitrilase from Rhodococcus rhodochrous J1 yields a stable, active helical form
RN Thuku, BW Weber, A Varsani, BT Sewell
The FEBS journal 274 (8), 2099-2108, 2007
922007
HIV-1 and SARS-CoV-2: Patterns in the evolution of two pandemic pathogens
W Fischer, EE Giorgi, S Chakraborty, K Nguyen, T Bhattacharya, J Theiler, ...
Cell host & microbe 29 (7), 1093-1110, 2021
852021
The cyanide degrading nitrilase from Pseudomonas stutzeri AK61 is a two-fold symmetric, 14-subunit spiral
BT Sewell, MN Berman, PR Meyers, D Jandhyala, MJ Benedik
Structure 11 (11), 1413-1422, 2003
812003
Comparison of cyanide-degrading nitrilases
DM Jandhyala, RC Willson, BT Sewell, MJ Benedik
Applied microbiology and biotechnology 68, 327-335, 2005
772005
A novel thermostable nitrilase superfamily amidase from Geobacillus pallidus showing acyl transfer activity
HS Makhongela, AE Glowacka, VB Agarkar, BT Sewell, B Weber, ...
Applied microbiology and biotechnology 75, 801-811, 2007
762007
Symmetry-restrained flexible fitting for symmetric EM maps
KY Chan, J Gumbart, R McGreevy, JM Watermeyer, BT Sewell, ...
Structure 19 (9), 1211-1218, 2011
742011
Cyanide bioremediation: the potential of engineered nitrilases
JM Park, B Trevor Sewell, MJ Benedik
Applied microbiology and biotechnology 101 (8), 3029-3042, 2017
702017
Genome mining of cyanide-degrading nitrilases from filamentous fungi
LJ Basile, RC Willson, BT Sewell, MJ Benedik
Applied microbiology and biotechnology 80, 427-435, 2008
682008
Selection analysis identifies clusters of unusual mutational changes in Omicron lineage BA. 1 that likely impact Spike function
DP Martin, S Lytras, AG Lucaci, W Maier, B Grüning, SD Shank, S Weaver, ...
Molecular Biology and Evolution 39 (4), msac061, 2022
672022
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