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Pedro Brugarolas, PhD
Pedro Brugarolas, PhD
Assistant Professor, Massachusetts General Hospital / Harvard Medical School
Dirección de correo verificada de mgh.harvard.edu - Página principal
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Pharmaceutical integrated stress response enhancement protects oligodendrocytes and provides a potential multiple sclerosis therapeutic
SW Way, JR Podojil, BL Clayton, A Zaremba, TL Collins, RB Kunjamma, ...
Nature communications 6 (1), 6532, 2015
1112015
Redox signaling in human pathogens
PR Chen, P Brugarolas, C He
Antioxidants & redox signaling 14 (6), 1107-1118, 2011
692011
The oxidation-sensing regulator (MosR) is a new redox-dependent transcription factor in Mycobacterium tuberculosis
P Brugarolas, F Movahedzadeh, Y Wang, N Zhang, IL Bartek, YN Gao, ...
Journal of biological chemistry 287 (45), 37703-37712, 2012
682012
Molecular mechanism of quinone signaling mediated through S-quinonization of a YodB family repressor QsrR
Q Ji, L Zhang, MB Jones, F Sun, X Deng, H Liang, H Cho, P Brugarolas, ...
Proceedings of the National Academy of Sciences 110 (13), 5010-5015, 2013
432013
Phosphorylation state of ZFP24 controls oligodendrocyte differentiation
B Elbaz, JD Aaker, S Isaac, A Kolarzyk, P Brugarolas, A Eden, B Popko
Cell reports 23 (8), 2254-2263, 2018
332018
Development of a PET radioligand for potassium channels to image CNS demyelination
P Brugarolas, JE Sánchez-Rodríguez, HM Tsai, F Basuli, SH Cheng, ...
Scientific reports 8 (1), 607, 2018
322018
Structure-activity relationship studies of four novel 4-aminopyridine K+ channel blockers
S Rodríguez-Rangel, AD Bravin, KM Ramos-Torres, P Brugarolas, ...
Scientific reports 10 (1), 52, 2020
302020
Evaluation of the potassium channel tracer [18F]3F4AP in rhesus macaques
NJ Guehl, KM Ramos-Torres, C Linnman, SH Moon, M Dhaynaut, ...
Journal of Cerebral Blood Flow & Metabolism 41 (7), 1721-1733, 2021
202021
Ordered circular mesoporosity induced by phospholipids
J García-Martínez, P Brugarolas, S Domínguez-Domínguez
Microporous and mesoporous materials 100 (1-3), 63-69, 2007
202007
Binding of ReO4 with an engineered MoO4 2−-binding protein: towards a new approach in radiopharmaceutical applications
BP Aryal, P Brugarolas, C He
JBIC Journal of Biological Inorganic Chemistry 17, 97-106, 2012
182012
Fifty years of radiopharmaceuticals
P Brugarolas, J Comstock, DW Dick, T Ellmer, JW Engle, SE Lapi, ...
Journal of nuclear medicine technology 48 (Supplement 1), 34S-39S, 2020
172020
Detecting demyelination by PET: the lesion as imaging target
P Brugarolas, DS Reich, B Popko
Molecular imaging 17, 1536012118785471, 2018
162018
Synthesis of meta-substituted [18 F] 3-fluoro-4-aminopyridine via direct radiofluorination of pyridine N-oxides
P Brugarolas, R Freifelder, SH Cheng, O DeJesus
Chemical communications 52 (44), 7150-7152, 2016
162016
Remyelination therapy goes to trial for multiple sclerosis
P Brugarolas, B Popko
Neuroimmunology & Neuroinflammation 1 (2), e26, 2014
162014
Structural and biochemical characterization of N5-carboxyaminoimidazole ribonucleotide synthetase and N5-carboxyaminoimidazole ribonucleotide mutase from Staphylococcus aureus
P Brugarolas, EM Duguid, W Zhang, CB Poor, C He
Acta Crystallographica Section D: Biological Crystallography 67 (8), 707-715, 2011
152011
An efficient new method for the synthesis of 3‐[18F]fluoro‐4‐aminopyridine via Yamada‐Curtius rearrangement
F Basuli, X Zhang, P Brugarolas, DS Reich, RE Swenson
Journal of Labelled Compounds and Radiopharmaceuticals 61 (2), 112-117, 2018
122018
Radiolabeling with [11C] HCN for positron emission tomography
YP Zhou, KJ Makaravage, P Brugarolas
Nuclear medicine and biology 102, 56-86, 2021
112021
Heterologous saRNA prime, DNA dual-antigen boost SARS-CoV-2 vaccination elicits robust cellular immunogenicity and cross-variant neutralizing antibodies
A Rice, M Verma, E Voigt, P Battisti, S Beaver, S Reed, K Dinkins, S Mody, ...
Frontiers in Immunology 13, 910136, 2022
72022
PET imaging of mitochondrial function in acute doxorubicin-induced cardiotoxicity: a proof-of-principle study
FJ Detmer, NM Alpert, SH Moon, M Dhaynaut, JL Guerrero, NJ Guehl, ...
Scientific Reports 12 (1), 6122, 2022
72022
Radiochemical Synthesis and Evaluation in Non-Human Primates of 3-[11C]methoxy-4-aminopyridine: A Novel PET Tracer for Imaging Potassium Channels in the …
NJ Guehl, R Neelamegam, YP Zhou, SH Moon, M Dhaynaut, G El Fakhri, ...
ACS chemical neuroscience 12 (4), 756-765, 2021
62021
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