Carbon monoxide has anti-inflammatory effects involving the mitogen-activated protein kinase pathway LE Otterbein, FH Bach, J Alam, M Soares, H Tao Lu, M Wysk, RJ Davis, ... Nature medicine 6 (4), 422-428, 2000 | 2708 | 2000 |
The therapeutic potential of carbon monoxide R Motterlini, LE Otterbein Nature reviews Drug discovery 9 (9), 728-743, 2010 | 1725 | 2010 |
Heme oxygenase-1: unleashing the protective properties of heme LE Otterbein, MP Soares, K Yamashita, FH Bach Trends in immunology 24 (8), 449-455, 2003 | 1449 | 2003 |
Carbon monoxide generated by heme oxygenase 1 suppresses endothelial cell apoptosis S Brouard, LE Otterbein, J Anrather, E Tobiasch, FH Bach, AMK Choi, ... The Journal of experimental medicine 192 (7), 1015-1026, 2000 | 1363 | 2000 |
Heme oxygenase: colors of defense against cellular stress LE Otterbein, AMK Choi American Journal of Physiology-Lung Cellular and Molecular Physiology 279 (6 …, 2000 | 1268 | 2000 |
The sedoheptulose kinase CARKL directs macrophage polarization through control of glucose metabolism A Haschemi, P Kosma, L Gille, CR Evans, CF Burant, P Starkl, B Knapp, ... Cell metabolism 15 (6), 813-826, 2012 | 693 | 2012 |
Heme oxygenase/carbon monoxide signaling path-ways: Regulation and functional significance SW Ryter, LE Otterbein, D Morse, AMK Choi Oxygen/Nitrogen Radicals: Cell Injury and Disease, 249-263, 2002 | 665 | 2002 |
Carbon monoxide suppresses arteriosclerotic lesions associated with chronic graft rejection and with balloon injury LE Otterbein, BS Zuckerbraun, M Haga, F Liu, R Song, A Usheva, ... Nature medicine 9 (2), 183-190, 2003 | 662 | 2003 |
Carbon monoxide provides protection against hyperoxic lung injury LE Otterbein, LL Mantell, AMK Choi American Journal of Physiology-Lung Cellular and Molecular Physiology 276 (4 …, 1999 | 642 | 1999 |
Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury LE Otterbein, JK Kolls, LL Mantell, JL Cook, J Alam, AMK Choi The Journal of clinical investigation 103 (7), 1047-1054, 1999 | 641 | 1999 |
Carbon monoxide generated by heme oxygenase-1 suppresses the rejection of mouse-to-rat cardiac transplants K Sato, J Balla, L Otterbein, RN Smith, S Brouard, Y Lin, E Csizmadia, ... The Journal of Immunology 166 (6), 4185-4194, 2001 | 640 | 2001 |
Carbon monoxide in biology and medicine SW Ryter, LE Otterbein Bioessays 26 (3), 270-280, 2004 | 511 | 2004 |
Suppression of inflammatory cytokine production by carbon monoxide involves the JNK pathway and AP-1 D Morse, SE Pischke, Z Zhou, RJ Davis, RA Flavell, T Loop, SL Otterbein, ... Journal of Biological Chemistry 278 (39), 36993-36998, 2003 | 477 | 2003 |
Heme oxygenase-1 inhibits TNF-α-induced apoptosis in cultured fibroblasts I Petrache, LE Otterbein, J Alam, GW Wiegand, AMK Choi American Journal of Physiology-Lung Cellular and Molecular Physiology 278 (2 …, 2000 | 472 | 2000 |
Metabolic control of type 1 regulatory T cell differentiation by AHR and HIF1-α ID Mascanfroni, MC Takenaka, A Yeste, B Patel, Y Wu, JE Kenison, ... Nature medicine 21 (6), 638-646, 2015 | 464 | 2015 |
Hemoglobin provides protection against lethal endotoxemia in rats: the role of heme oxygenase-1. L Otterbein, SL Sylvester, AM Choi American journal of respiratory cell and molecular biology 13 (5), 595-601, 1995 | 404 | 1995 |
Autoantibodies in patients with chronic obstructive pulmonary disease CA Feghali-Bostwick, AS Gadgil, LE Otterbein, JM Pilewski, MW Stoner, ... American journal of respiratory and critical care medicine 177 (2), 156-163, 2008 | 399 | 2008 |
Carbon monoxide signals via inhibition of cytochrome c oxidase and generation of mitochondrial reactive oxygen species BS Zuckerbraun, BY Chin, M Bilban, JC d'Avila, J Rao, TR Billiar, ... The FASEB Journal 21 (4), 1099-1106, 2007 | 379 | 2007 |
Carbon monoxide expedites metabolic exhaustion to inhibit tumor growth B Wegiel, D Gallo, E Csizmadia, C Harris, J Belcher, GM Vercellotti, ... Cancer research 73 (23), 7009-7021, 2013 | 368 | 2013 |
Carbon monoxide inhibition of apoptosis during ischemia-reperfusion lung injury is dependent on the p38 mitogen-activated protein kinase pathway and involves caspase 3 X Zhang, P Shan, LE Otterbein, J Alam, RA Flavell, RJ Davis, AMK Choi, ... Journal of Biological Chemistry 278 (2), 1248-1258, 2003 | 358 | 2003 |