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Akil Merchant
Akil Merchant
Dirección de correo verificada de cshs.org
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Targeting Hedgehog—a cancer stem cell pathway
AA Merchant, W Matsui
Clinical cancer research 16 (12), 3130-3140, 2010
6142010
Molecular signatures of proliferation and quiescence in hematopoietic stem cells
TA Venezia, AA Merchant, CA Ramos, NL Whitehouse, AS Young, ...
PLoS biology 2 (10), e301, 2004
4272004
Hematopoietic fingerprints: an expression database of stem cells and their progeny
SM Chambers, NC Boles, KYK Lin, MP Tierney, TV Bowman, SB Bradfute, ...
Cell stem cell 1 (5), 578-591, 2007
3242007
GLI1 is a direct transcriptional target of EWS-FLI1 oncoprotein
E Beauchamp, G Bulut, O Abaan, K Chen, A Merchant, W Matsui, Y Endo, ...
Journal of Biological Chemistry 284 (14), 9074-9082, 2009
1842009
Single-cell transcriptome analysis reveals disease-defining T-cell subsets in the tumor microenvironment of classic Hodgkin lymphoma
T Aoki, LC Chong, K Takata, K Milne, M Hav, A Colombo, EA Chavez, ...
Cancer discovery 10 (3), 406-421, 2020
1782020
Hepatic adverse event profile of inotuzumab ozogamicin in adult patients with relapsed or refractory acute lymphoblastic leukaemia: results from the open-label, randomised …
HM Kantarjian, DJ DeAngelo, AS Advani, M Stelljes, P Kebriaei, ...
The Lancet Haematology 4 (8), e387-e398, 2017
1662017
Gli1 regulates the proliferation and differentiation of HSCs and myeloid progenitors
A Merchant, G Joseph, Q Wang, S Brennan, W Matsui
Blood, The Journal of the American Society of Hematology 115 (12), 2391-2396, 2010
1282010
The redox-sensitive transcription factor Nrf2 regulates murine hematopoietic stem cell survival independently of ROS levels
AA Merchant, A Singh, W Matsui, S Biswal
Blood, The Journal of the American Society of Hematology 118 (25), 6572-6579, 2011
1262011
Glasdegib in combination with cytarabine and daunorubicin in patients with AML or high‐risk MDS: phase 2 study results
JE Cortes, B Douglas Smith, ES Wang, A Merchant, VG Oehler, ...
American journal of hematology 93 (11), 1301-1310, 2018
1232018
Not so benign haematology: anaemia of the elderly
AA Merchant, CN Roy
British journal of haematology 156 (2), 173-185, 2012
1112012
Management of important adverse events associated with inotuzumab ozogamicin: expert panel review
P Kebriaei, C Cutler, M De Lima, S Giralt, SJ Lee, D Marks, A Merchant, ...
Bone marrow transplantation 53 (4), 449-456, 2018
1062018
Self-renewal of acute lymphocytic leukemia cells is limited by the Hedgehog pathway inhibitors cyclopamine and IPI-926
TL Lin, QH Wang, P Brown, C Peacock, AA Merchant, S Brennan, E Jones, ...
Plos one 5 (12), e15262, 2010
1012010
Periodontal inflammation recruits distant metastatic breast cancer cells by increasing myeloid-derived suppressor cells
R Cheng, S Billet, C Liu, S Haldar, D Choudhury, M Tripathi, M Hav, ...
Oncogene 39 (7), 1543-1556, 2020
702020
Multiplex protein detection on circulating tumor cells from liquid biopsies using imaging mass cytometry
E Gerdtsson, M Pore, JA Thiele, AS Gerdtsson, PD Malihi, R Nevarez, ...
Convergent science physical oncology 4 (1), 015002, 2018
692018
GLI3 repressor determines Hedgehog pathway activation and is required for response to SMO antagonist glasdegib in AML
P Chaudhry, M Singh, TJ Triche, M Guzman, AA Merchant
Blood, The Journal of the American Society of Hematology 129 (26), 3465-3475, 2017
692017
Integration of Hedgehog and mutant FLT3 signaling in myeloid leukemia
Y Lim, L Gondek, L Li, Q Wang, H Ma, E Chang, DL Huso, S Foerster, ...
Science translational medicine 7 (291), 291ra96-291ra96, 2015
612015
Evidence for diversity in transcriptional profiles of single hematopoietic stem cells
CA Ramos, TA Bowman, NC Boles, AA Merchant, Y Zheng, I Parra, ...
PLoS genetics 2 (9), e159, 2006
612006
Outcomes of allogeneic stem cell transplantation after inotuzumab ozogamicin treatment for relapsed or refractory acute lymphoblastic leukemia
DI Marks, P Kebriaei, M Stelljes, N Gökbuget, H Kantarjian, AS Advani, ...
Biology of Blood and Marrow Transplantation 25 (9), 1720-1729, 2019
572019
Primary cilia are present on human blood and bone marrow cells and mediate Hedgehog signaling
M Singh, P Chaudhry, AA Merchant
Experimental Hematology 44 (12), 1181-1187. e2, 2016
552016
Glasdegib plus intensive/nonintensive chemotherapy in untreated acute myeloid leukemia: BRIGHT AML 1019 Phase III trials
JE Cortes, H Dombret, A Merchant, T Tauchi, CG DiRienzo, B Sleight, ...
Future Oncology 15 (31), 3531-3545, 2019
492019
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