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Helena Cocheme
Helena Cocheme
MRC Laboratory of Medical Sciences (LMS), Imperial College London
Dirección de correo verificada de lms.mrc.ac.uk - Página principal
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Metformin retards aging in C. elegans by altering microbial folate and methionine metabolism
F Cabreiro, C Au, KY Leung, N Vergara-Irigaray, HM Cochemé, T Noori, ...
Cell 153 (1), 228-239, 2013
9872013
Complex I is the major site of mitochondrial superoxide production by paraquat
HM Cochemé, MP Murphy
Journal of biological chemistry 283 (4), 1786-1798, 2008
6682008
Cardioprotection by S-nitrosation of a cysteine switch on mitochondrial complex I
ET Chouchani, C Methner, SM Nadtochiy, A Logan, VR Pell, S Ding, ...
Nature medicine 19 (6), 753-759, 2013
6462013
Lipophilic triphenylphosphonium cations as tools in mitochondrial bioenergetics and free radical biology
MF Ross, GF Kelso, FH Blaikie, AM James, HM Cocheme, A Filipovska, ...
Biochemistry (Moscow) 70, 222-230, 2005
5492005
Mitochondrial pharmacology
RAJ Smith, RC Hartley, HM Cocheme, MP Murphy
Trends in pharmacological sciences 33 (6), 341-352, 2012
5442012
Interactions of Mitochondria-targeted and Untargeted Ubiquinones with the Mitochondrial Respiratory Chain and Reactive Oxygen Species: IMPLICATIONS FOR THE USE OF EXOGENOUS …
AM James, HM Cochemé, RAJ Smith, MP Murphy
Journal of Biological Chemistry 280 (22), 21295-21312, 2005
4532005
Mitochondria-Targeted Antioxidant MitoQ10 Improves Endothelial Function and Attenuates Cardiac Hypertrophy
D Graham, NN Huynh, CA Hamilton, E Beattie, RAJ Smith, HM Cochemé, ...
Hypertension 54 (2), 322-328, 2009
4002009
Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from …
MP Murphy, KS Echtay, FH Blaikie, J Asin-Cayuela, HM Cochemé, ...
Journal of Biological Chemistry 278 (49), 48534-48545, 2003
3712003
Redox metabolism: ROS as specific molecular regulators of cell signaling and function
C Lennicke, HM Cochemé
Molecular Cell 81 (18), 3691-3707, 2021
3702021
Measurement of H2O2 within living Drosophila during aging using a ratiometric mass spectrometry probe targeted to the mitochondrial matrix
HM Cochemé, C Quin, SJ McQuaker, F Cabreiro, A Logan, TA Prime, ...
Cell metabolism 13 (3), 340-350, 2011
3192011
Mitochondrial redox signalling at a glance
Y Collins, ET Chouchani, AM James, KE Menger, HM Cochemé, ...
Journal of cell science 125 (4), 801-806, 2012
3152012
Consequences of long-term oral administration of the mitochondria-targeted antioxidant MitoQ to wild-type mice
S Rodriguez-Cuenca, HM Cochemé, A Logan, I Abakumova, TA Prime, ...
Free Radical Biology and Medicine 48 (1), 161-172, 2010
2392010
Host-microbe-drug-nutrient screen identifies bacterial effectors of metformin therapy
R Pryor, P Norvaisas, G Marinos, L Best, LB Thingholm, LM Quintaneiro, ...
Cell 178 (6), 1299-1312. e29, 2019
1972019
Oxidative stress and life histories: unresolved issues and current needs
JR Speakman, JD Blount, AM Bronikowski, R Buffenstein, C Isaksson, ...
Ecology and Evolution 5 (24), 5745-5757, 2015
1972015
Loss of PLA2G6 leads to elevated mitochondrial lipid peroxidation and mitochondrial dysfunction
KJ Kinghorn, JI Castillo-Quan, F Bartolome, PR Angelova, L Li, S Pope, ...
Brain 138 (7), 1801-1816, 2015
1812015
Mitochondrial targeting of quinones: therapeutic implications
HM Cochemé, GF Kelso, AM James, MF Ross, J Trnka, T Mahendiran, ...
Mitochondrion 7, S94-S102, 2007
1622007
Genome‐wide dFOXO targets and topology of the transcriptomic response to stress and insulin signalling
N Alic, TD Andrews, ME Giannakou, I Papatheodorou, C Slack, ...
Molecular systems biology 7 (1), 502, 2011
1432011
Mitochondria‐targeted antioxidants in the treatment of disease
RAJ Smith, VJ Adlam, FH Blaikie, ARB Manas, CM Porteous, AM James, ...
Annals of the New York Academy of Sciences 1147 (1), 105-111, 2008
1322008
Using the mitochondria-targeted ratiometric mass spectrometry probe MitoB to measure H2O2 in living Drosophila
HM Cochemé, A Logan, TA Prime, I Abakumova, C Quin, SJ McQuaker, ...
Nature protocols 7 (5), 946-958, 2012
1292012
Direct Keap1-Nrf2 disruption as a potential therapeutic target for Alzheimer’s disease
F Kerr, O Sofola-Adesakin, DK Ivanov, J Gatliff, B Gomez Perez-Nievas, ...
PLoS genetics 13 (3), e1006593, 2017
1282017
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Artículos 1–20