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Chas Bountra
Chas Bountra
Professor of Translational Medicine
Verified email at cmd.ox.ac.uk
Title
Cited by
Cited by
Year
Epigenetic protein families: a new frontier for drug discovery
CH Arrowsmith, C Bountra, PV Fish, K Lee, M Schapira
Nature reviews Drug discovery 11 (5), 384-400, 2012
15952012
Disruption of the P2X7 purinoceptor gene abolishes chronic inflammatory and neuropathic pain
IP Chessell, JP Hatcher, C Bountra, AD Michel, JP Hughes, P Green, ...
Pain 114 (3), 386-396, 2005
9832005
A selective jumonji H3K27 demethylase inhibitor modulates the proinflammatory macrophage response
L Kruidenier, C Chung, Z Cheng, J Liddle, KH Che, G Joberty, ...
Nature 488 (7411), 404-408, 2012
9762012
The promise and peril of chemical probes
CH Arrowsmith, JE Audia, C Austin, J Baell, J Bennett, J Blagg, C Bountra, ...
Nature chemical biology 11 (8), 536-541, 2015
8602015
Increased mast cells in the irritable bowel syndrome
Clayton, Breslin, Harman, Bountra, Mclaren
Neurogastroenterology & Motility 12 (5), 449-457, 2000
6302000
COX-2, CB2 and P2X7-immunoreactivities are increased in activated microglial cells/macrophages of multiple sclerosis and amyotrophic lateral sclerosis spinal cord
Y Yiangou, P Facer, P Durrenberger, IP Chessell, A Naylor, C Bountra, ...
BMC neurology 6, 1-14, 2006
5582006
RVX-208, an inhibitor of BET transcriptional regulators with selectivity for the second bromodomain
S Picaud, C Wells, I Felletar, D Brotherton, S Martin, P Savitsky, ...
Proceedings of the National Academy of Sciences 110 (49), 19754-19759, 2013
4952013
Sensory fibres expressing capsaicin receptor TRPV1 in patients with rectal hypersensitivity and faecal urgency
CLH Chan, P Facer, JB Davis, GD Smith, J Egerton, C Bountra, ...
The Lancet 361 (9355), 385-391, 2003
4412003
Differential expression of the capsaicin receptor TRPV1 and related novel receptors TRPV3, TRPV4 and TRPM8 in normal human tissues and changes in traumatic and diabetic neuropathy
P Facer, MA Casula, GD Smith, CD Benham, IP Chessell, C Bountra, ...
BMC neurology 7, 1-12, 2007
3432007
Burning mouth syndrome as a trigeminal small fibre neuropathy: Increased heat and capsaicin receptor TRPV1 in nerve fibres correlates with pain score
Z Yilmaz, T Renton, Y Yiangou, J Zakrzewska, IP Chessell, C Bountra, ...
Journal of Clinical Neuroscience 14 (9), 864-871, 2007
3372007
Immunolocalization of SNS/PN3 and NaN/SNS2 sodium channels in human pain states
K Coward, C Plumpton, P Facer, R Birch, T Carlstedt, S Tate, C Bountra, ...
Pain 85 (1-2), 41-50, 2000
3372000
Two sodium channels contribute to the TTX-R sodium current in primary sensory neurons
S Tate, S Benn, C Hick, D Trezise, V John, RJ Mannion, M Costigan, ...
Nature neuroscience 1 (8), 653-655, 1998
3341998
CB1 and CB2 cannabinoid receptors are implicated in inflammatory pain
N Clayton, FH Marshall, C Bountra, CT O'shaughnessy
Pain 96 (3), 253-260, 2002
3322002
Structures of ABCB10, a human ATP-binding cassette transporter in apo-and nucleotide-bound states
CA Shintre, ACW Pike, Q Li, JI Kim, AJ Barr, S Goubin, L Shrestha, J Yang, ...
Proceedings of the National Academy of Sciences 110 (24), 9710-9715, 2013
2802013
Generation of a selective small molecule inhibitor of the CBP/p300 bromodomain for leukemia therapy
S Picaud, O Fedorov, A Thanasopoulou, K Leonards, K Jones, J Meier, ...
Cancer research 75 (23), 5106-5119, 2015
2532015
An fMRI study of cerebral processing of brush-evoked allodynia in neuropathic pain patients
P Schweinhardt, C Glynn, J Brooks, H McQuay, T Jack, I Chessell, ...
Neuroimage 32 (1), 256-265, 2006
2452006
EMA401, an orally administered highly selective angiotensin II type 2 receptor antagonist, as a novel treatment for postherpetic neuralgia: a randomised, double-blind, placebo …
ASC Rice, RH Dworkin, TD McCarthy, P Anand, C Bountra, PI McCloud, ...
The Lancet 383 (9929), 1637-1647, 2014
2352014
Prepublication data sharing
Toronto International Data Release Workshop Authors
Nature 461 (7261), 168-170, 2009
2202009
The 5-HT3 receptor antagonist alosetron inhibits the colorectal distention induced depressor response and spinalc-fos expression in the anaesthetised rat
CM Kozlowski, A Green, D Grundy, FM Boissonade, C Bountra
Gut 46 (4), 474-480, 2000
2092000
Cool and menthol receptor TRPM8 in human urinary bladder disorders and clinical correlations
G Mukerji, Y Yiangou, SL Corcoran, IS Selmer, GD Smith, CD Benham, ...
BMC urology 6, 1-11, 2006
2042006
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