Benzene and Its Phenolic Metabolites Produce Oxidative DNA Damage in HL60 Cells in Vitro and in the Bone Marrow in Vivo P Kolachana, VV Subrahmanyam, KB Meyer, L Zhang, MT Smith Cancer research 53 (5), 1023-1026, 1993 | 295 | 1993 |
Identification of cytochrome P-450 isoforms responsible for cis-tramadol metabolism in human liver microsomes V Subrahmanyam, AB Renwick, DG Walters, PJ Young, RJ Price, ... Drug Metabolism and Disposition 29 (8), 1146-1155, 2001 | 255 | 2001 |
Mechanism-based models in reproductive and developmental toxicology D Pamies, CE Martínez, MA Sogorb, E Vilanova Reproductive and developmental toxicology, 135-146, 2011 | 208 | 2011 |
Synergistic interactions among flavonoids and acetogenins in Graviola (Annona muricata) leaves confer protection against prostate cancer C Yang, SR Gundala, R Mukkavilli, S Vangala, MD Reid, R Aneja Carcinogenesis 36 (6), 656-665, 2015 | 201 | 2015 |
Potential Role of Free Radicals in Benzene induced myelotoxicity and leukemia VV SUBRAHMANYAM, D ROSS, DA EASTMOND, MT SMITH Free Radical Biology & Medicine 11, 495-55, 1991 | 197 | 1991 |
Metabolite identification by data‐dependent accurate mass spectrometric analysis at resolving power of 60 000 in external calibration mode using an LTQ/Orbitrap HK Lim, J Chen, C Sensenhauser, K Cook, V Subrahmanyam Rapid Communications in Mass Spectrometry: An International Journal Devoted …, 2007 | 132 | 2007 |
Effects of phosphodiesterase 3, 4, 5 inhibitors on hepatocyte cAMP levels, glycogenolysis, gluconeogenesis and suceptibility to a mitochondrial toxin M Abdollahi, TS Chan, V Subrahmanyam, PJ O'brien Molecular and cellular biochemistry 252, 205-211, 2003 | 109 | 2003 |
Bone marrow stromal cell bioactivation and detoxification of the benzene metabolite hydroquinone: comparison of macrophages and fibroblastoid cells. DJ Thomas, A Sadler, VV Subrahmanyam, D Siegel, MJ Reasor, ... Molecular pharmacology 37 (2), 255-262, 1990 | 105 | 1990 |
Oxidation of catechol by horseradish peroxidase and human leukocyte peroxidase: reactions of o-benzoquinone and o-benzosemiquinone A Sadler, VV Subrahmanyam, D Ross Toxicology and applied pharmacology 93 (1), 62-71, 1988 | 93 | 1988 |
Metabolism of hydroquinone by human myeloperoxidase: mechanisms of stimulation by other phenolic compounds VV Subrahmanyam, P Kolachana, MT Smith Archives of biochemistry and biophysics 286 (1), 76-84, 1991 | 83 | 1991 |
Phenol-induced stimulation of hydroquinone bioactivation in mouse bone marrow in vivo: possible implications in benzene myelotoxicity VV Subrahmanyam, P Doane-Setzer, KL Steinmetz, D Ross, MT Smith Toxicology 62 (1), 107-116, 1990 | 82 | 1990 |
PhRMA white paper on ADME pharmacogenomics JA Williams, T Andersson, TB Andersson, R Blanchard, MO Behm, ... The Journal of Clinical Pharmacology 48 (7), 849-889, 2008 | 77 | 2008 |
Probable free radical effects on rat liver nuclei during early hepatocarcinogenesis with a choline-devoid low methionine diet GAK Rushmore TH, Ghazarian DM, Subrahmanyan V, Farber E Cancer research 47 (24; Part I), 6731-6740, 1987 | 72 | 1987 |
Application of combination high‐throughput phenotypic screening and target identification methods for the discovery of natural product‐based combination drugs M Isgut, M Rao, C Yang, V Subrahmanyam, PCG Rida, R Aneja Medicinal research reviews 38 (2), 504-524, 2018 | 61 | 2018 |
Biomarkers, metabonomics, and drug development: can inborn errors of metabolism help in understanding drug toxicity? S Vangala, A Tonelli The AAPS journal 9, E284-E297, 2007 | 59 | 2007 |
Enterohepatic recirculation of bioactive ginger phytochemicals is associated with enhanced tumor growth-inhibitory activity of ginger extract SR Gundala, R Mukkavilli, C Yang, P Yadav, V Tandon, S Vangala, ... Carcinogenesis 35 (6), 1320-1329, 2014 | 57 | 2014 |
Bioactivation of catechol in rat and human bone marrow cells RV Bhat, VV Subrahmanyam, A Sadler, D Ross Toxicology and applied pharmacology 94 (2), 297-304, 1988 | 54 | 1988 |
Peroxidase catalysed oxygen activation by arylamine carcinogens and phenol VV Subrahmanyam, PJ O'Brien Chemico-biological interactions 56 (2-3), 185-199, 1985 | 53 | 1985 |
Hydroxylation of phenol to hydroquinone catalyzed by a human myeloperoxidase-superoxide complex: possible implications in benzene-induced myelotoxicity VV Subrahmanyam, P Kolachana, MT Smith Free radical research communications 15 (5), 285-296, 1991 | 49 | 1991 |
Modulation of cytochrome P450 metabolism and transport across intestinal epithelial barrier by ginger biophenolics R Mukkavilli, SR Gundala, C Yang, S Donthamsetty, G Cantuaria, ... PloS one 9 (9), e108386, 2014 | 47 | 2014 |