Biosynthesis of cholesterol and other sterols WD Nes Chemical reviews 111 (10), 6423-6451, 2011 | 639 | 2011 |
STEROL METHYLTRANSFERASE 1 Controls the Level of Cholesterol in Plants AC Diener, H Li, W Zhou, WJ Whoriskey, WD Nes, GR Fink The Plant Cell 12 (6), 853-870, 2000 | 334 | 2000 |
Insect sterol nutrition and physiology: a global overview ST Behmer, WD Nes Advances in insect physiology 31 (03), 1-72, 2003 | 299 | 2003 |
Characterization and catalytic properties of the sterol 14α-demethylase from Mycobacterium tuberculosis A Bellamine, AT Mangla, WD Nes, MR Waterman Proceedings of the National Academy of Sciences 96 (16), 8937-8942, 1999 | 258 | 1999 |
Identification of natural RORγ ligands that regulate the development of lymphoid cells FR Santori, P Huang, SA van de Pavert, EF Douglass, DJ Leaver, ... Cell metabolism 21 (2), 286-298, 2015 | 230 | 2015 |
The functional importance of structural features of ergosterol in yeast. WR Nes, BC Sekula, WD Nes, JH Adler Journal of Biological Chemistry 253 (17), 6218-6225, 1978 | 216 | 1978 |
Sterol methyl transferase: enzymology and inhibition WD Nes Biochimica et Biophysica Acta (BBA)-Molecular and Cell Biology of Lipids …, 2000 | 171 | 2000 |
Developmental regulation of sterol biosynthesis inZea mays D Guo, M Venkatramesh, WD Nes Lipids 30, 203-219, 1995 | 165 | 1995 |
Lipids in Evolution WR Nes, WD Nes | 163* | 1980 |
Sterol 14α-demethylase as a potential target for antitrypanosomal therapy: enzyme inhibition and parasite cell growth GI Lepesheva, RD Ott, TY Hargrove, YY Kleshchenko, I Schuster, WD Nes, ... Chemistry & biology 14 (11), 1283-1293, 2007 | 160 | 2007 |
The phylogenetic distribution of sterols in tracheophytes WR Nes, K Krevitz, J Joseph, WD Nes, B Harris, GF Gibbons, ... Lipids 12 (6), 511-527, 1977 | 152 | 1977 |
CYP51 from Trypanosoma cruzi: a phyla-specific residue in the B′ helix defines substrate preferences of sterol 14α-demethylase GI Lepesheva, NG Zaitseva, WD Nes, W Zhou, M Arase, J Liu, GC Hill, ... Journal of Biological Chemistry 281 (6), 3577-3585, 2006 | 148 | 2006 |
Carbon-13 NMR studies on sitosterol biosynthesized from [13C] mevalonates WD Nes, RA Norton, M Benson Phytochemistry 31 (3), 805-811, 1992 | 137 | 1992 |
Crystal Structures of Trypanosoma brucei Sterol 14α-Demethylase and Implications for Selective Treatment of Human Infections*♦ GI Lepesheva, HW Park, TY Hargrove, B Vanhollebeke, Z Wawrzak, ... Journal of Biological Chemistry 285 (3), 1773-1780, 2010 | 133 | 2010 |
Azole Binding Properties of Candida albicans Sterol 14-α Demethylase (CaCYP51) AGS Warrilow, CM Martel, JE Parker, N Melo, DC Lamb, WD Nes, ... Antimicrobial agents and chemotherapy 54 (10), 4235-4245, 2010 | 131 | 2010 |
Identification of the lipophilic factor produced by macrophages that stimulates steroidogenesis WD Nes, YO Lukyanenko, ZH Jia, S Quideau, WN Howald, TK Pratum, ... Endocrinology 141 (3), 953-958, 2000 | 128 | 2000 |
Comparison of the chromatographic properties of sterols, select additional steroids and triterpenoids: gravity-flow column liquid chromatography, thin-layer chromatography, gas … S Xu, RA Norton, FG Crumley, WD Nes Journal of chromatography A 452, 377-398, 1988 | 126 | 1988 |
The structural requirements of sterols for membrane function in Saccharomyces cerevisiae WD Nes, GG Janssen, FG Crumley, M Kalinowska, T Akihisa Archives of biochemistry and biophysics 300 (2), 724-733, 1993 | 125 | 1993 |
Substrate preferences and catalytic parameters determined by structural characteristics of sterol 14α-demethylase (CYP51) from Leishmania infantum TY Hargrove, Z Wawrzak, J Liu, WD Nes, MR Waterman, GI Lepesheva Journal of Biological Chemistry 286 (30), 26838-26848, 2011 | 121 | 2011 |
CYP51: A major drug target in the cytochrome P450 superfamily GI Lepesheva, TY Hargrove, Y Kleshchenko, WD Nes, F Villalta, ... Lipids 43, 1117-1125, 2008 | 121 | 2008 |