| Dynamic modelling of oestrogen signalling and cell fate in breast cancer cells JJ Tyson, WT Baumann, C Chen, A Verdugo, I Tavassoly, Y Wang, ... Nature Reviews Cancer 11 (7), 523-532, 2011 | 223 | 2011 |
| Myeloid cell-derived inducible nitric oxide synthase suppresses M1 macrophage polarization G Lu, R Zhang, S Geng, L Peng, P Jayaraman, C Chen, F Xu, J Yang, Q Li, ... Nature communications 6 (1), 6676, 2015 | 202 | 2015 |
| The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis S Geng, K Chen, R Yuan, L Peng, U Maitra, N Diao, C Chen, Y Zhang, ... Nature communications 7 (1), 13436, 2016 | 174 | 2016 |
| Modeling of the role of a Bax-activation switch in the mitochondrial apoptosis decision C Chen, J Cui, H Lu, R Wang, S Zhang, P Shen Biophysical journal 92 (12), 4304-4315, 2007 | 132 | 2007 |
| Identification of human liver mitochondrial aldehyde dehydrogenase as a potential target for microcystin-LR T Chen, J Cui, Y Liang, X Xin, DO Young, C Chen, P Shen Toxicology 220 (1), 71-80, 2006 | 88 | 2006 |
| Two independent positive feedbacks and bistability in the Bcl-2 apoptotic switch J Cui, C Chen, H Lu, T Sun, P Shen PLoS One 3 (1), e1469, 2008 | 82 | 2008 |
| Upstream process intensification and continuous manufacturing C Chen, HE Wong, CT Goudar Current Opinion in Chemical Engineering 22, 191-198, 2018 | 71 | 2018 |
| Modeling the role of p53 pulses in DNA damage-induced cell death decision T Sun, C Chen, Y Wu, S Zhang, J Cui, P Shen BMC bioinformatics 10, 1-12, 2009 | 63 | 2009 |
| Endoplasmic reticulum stress, the unfolded protein response, and gene network modeling in antiestrogen resistant breast cancer R Clarke, AN Shajahan, Y Wang, JJ Tyson, RB Riggins, LM Weiner, ... Hormone Molecular Biology and Clinical Investigation, 2011 | 62 | 2011 |
| Robustness analysis identifies the plausible model of the Bcl-2 apoptotic switch C Chen, J Cui, W Zhang, P Shen FEBS letters 581 (26), 5143-5150, 2007 | 59 | 2007 |
| Reprogramming macrophage orientation by microRNA 146b targeting transcription factor IRF5 L Peng, H Zhang, Y Hao, F Xu, J Yang, R Zhang, G Lu, Z Zheng, M Cui, ... EBioMedicine 14, 83-96, 2016 | 58 | 2016 |
| Modeling the estrogen receptor to growth factor receptor signaling switch in human breast cancer cells C Chen, WT Baumann, R Clarke, JJ Tyson FEBS letters 587 (20), 3327-3334, 2013 | 36 | 2013 |
| Interferon regulatory factor-1 signaling regulates the switch between autophagy and apoptosis to determine breast cancer cell fate JL Schwartz-Roberts, KL Cook, C Chen, AN Shajahan-Haq, M Axelrod, ... Cancer research 75 (6), 1046-1055, 2015 | 35 | 2015 |
| Mathematical models of the transitions between endocrine therapy responsive and resistant states in breast cancer C Chen, WT Baumann, J Xing, L Xu, R Clarke, JJ Tyson Journal of The Royal Society Interface 11 (96), 20140206, 2014 | 32 | 2014 |
| Assuring Clonality on the Beacon Digital Cell Line Development Platform K Le, C Tan, H Le, J Tat, E Zasadzinska, J Diep, R Zastrow, C Chen, ... Biotechnology Journal, 2019 | 31 | 2019 |
| Integration of systems biology in cell line and process development for biopharmaceutical manufacturing C Chen, H Le, CT Goudar Biochemical Engineering Journal 107, 11-17, 2016 | 23 | 2016 |
| An automated RNA‐Seq analysis pipeline to identify and visualize differentially expressed genes and pathways in CHO cells C Chen, H Le, CT Goudar Biotechnology progress 31 (5), 1150-1162, 2015 | 19 | 2015 |
| Transcription Dependent and Independent Roles of p53 in Apoptosis Regulation [J] TZ Sun, C Chen, PP Shen Chinese Journal of Cell Biology 3, 007, 2008 | 15* | 2008 |
| Evaluation of two public genome references for chinese hamster ovary cells in the context of rna‐seq based gene expression analysis C Chen, H Le, CT Goudar Biotechnology and Bioengineering 114 (7), 1603-1613, 2017 | 14 | 2017 |
| An evaluation of public genomic references for mapping RNA‐Seq data from Chinese hamster ovary cells H Le, C Chen, CT Goudar Biotechnology and bioengineering 112 (11), 2412-2416, 2015 | 14 | 2015 |
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