Potential role of intratumor bacteria in mediating tumor resistance to the chemotherapeutic drug gemcitabine LT Geller, M Barzily-Rokni, T Danino, OH Jonas, N Shental, D Nejman, ... Science 357 (6356), 1156-1160, 2017 | 1308 | 2017 |
Direct evidence for cancer-cell-autonomous extracellular protein catabolism in pancreatic tumors SM Davidson, O Jonas, MA Keibler, HW Hou, A Luengo, JR Mayers, ... Nature medicine 23 (2), 235-241, 2017 | 299 | 2017 |
Tumor cell–driven extracellular matrix remodeling drives haptotaxis during metastatic progression MJ Oudin, O Jonas, T Kosciuk, LC Broye, BC Guido, J Wyckoff, ... Cancer discovery 6 (5), 516-531, 2016 | 205 | 2016 |
An implantable microdevice to perform high-throughput in vivo drug sensitivity testing in tumors O Jonas, HM Landry, JE Fuller, JT Santini Jr, J Baselga, RI Tepper, ... Science translational medicine 7 (284), 284ra57-284ra57, 2015 | 181 | 2015 |
Microenvironment-mediated mechanisms of resistance to HER2 inhibitors differ between HER2+ breast cancer subtypes SS Watson, M Dane, K Chin, Z Tatarova, M Liu, T Liby, W Thompson, ... Cell systems 6 (3), 329-342. e6, 2018 | 82 | 2018 |
Invasive cancer cell lines exhibit biomechanical properties that are distinct from their noninvasive counterparts O Jonas, CT Mierke, JA Käs Soft Matter 7 (24), 11488-11495, 2011 | 68 | 2011 |
Tyrosine kinase inhibitors increase MCL1 degradation and in combination with BCLXL/BCL2 inhibitors drive prostate cancer apoptosis S Arai, O Jonas, MA Whitman, E Corey, SP Balk, S Chen Clinical Cancer Research 24 (21), 5458-5470, 2018 | 54 | 2018 |
Integrated genetic and pharmacologic interrogation of rare cancers AL Hong, YY Tseng, GS Cowley, O Jonas, JH Cheah, BD Kynnap, ... Nature communications 7 (1), 11987, 2016 | 53 | 2016 |
MENA confers resistance to paclitaxel in triple-negative breast cancer MJ Oudin, L Barbier, C Schäfer, T Kosciuk, MA Miller, S Han, O Jonas, ... Molecular cancer therapeutics 16 (1), 143-155, 2017 | 44 | 2017 |
First in vivo testing of compounds targeting group 3 medulloblastomas using an implantable microdevice as a new paradigm for drug development O Jonas, D Calligaris, KR Methuku, MM Poe, JP Francois, F Tranghese, ... Journal of biomedical nanotechnology 12 (6), 1297-1302, 2016 | 42 | 2016 |
Genome-wide interrogation of human cancers identifies EGLN1 dependency in clear cell ovarian cancers C Price, S Gill, ZV Ho, SM Davidson, E Merkel, JM McFarland, L Leung, ... Cancer research 79 (10), 2564-2579, 2019 | 35 | 2019 |
Force propagation and force generation in cells O Jonas, C Duschl Cytoskeleton 67 (9), 555-563, 2010 | 35 | 2010 |
REV1 inhibitor JH-RE-06 enhances tumor cell response to chemotherapy by triggering senescence hallmarks N Chatterjee, MA Whitman, CA Harris, SM Min, O Jonas, EC Lien, ... Proceedings of the National Academy of Sciences 117 (46), 28918-28921, 2020 | 32 | 2020 |
Synergistic interactions with PI3K inhibition that induce apoptosis Y Zwang, O Jonas, C Chen, ML Rinne, JG Doench, F Piccioni, L Tan, ... elife 6, e24523, 2017 | 32 | 2017 |
VISAGE reveals a targetable mitotic spindle vulnerability in cancer cells JC Patterson, BA Joughin, AE Prota, T Mühlethaler, OH Jonas, ... Cell systems 9 (1), 74-92. e8, 2019 | 27 | 2019 |
Surface characterization and investigation on antibacterial activity of CuZn nanofibers prepared by electrospinning A Choi, J Park, J Kang, O Jonas, D Kim, H Kim, JW Oh, YC Kang Applied Surface Science 508, 144883, 2020 | 24 | 2020 |
A multiplex implantable microdevice assay identifies synergistic combinations of cancer immunotherapies and conventional drugs Z Tatarova, DC Blumberg, JE Korkola, LM Heiser, JL Muschler, ... Nature biotechnology 40 (12), 1823-1833, 2022 | 22 | 2022 |
Parallel In Vivo Assessment of Drug Phenotypes at Various Time Points during Systemic BRAF Inhibition Reveals Tumor Adaptation and Altered Treatment … O Jonas, MJ Oudin, T Kosciuk, M Whitman, FB Gertler, MJ Cima, ... Clinical Cancer Research 22 (24), 6031-6038, 2016 | 22 | 2016 |
Development of a novel probe for measuring drug binding to the F1* S variant of human alpha 1‐acid glycoprotein LP Cogswell III, DE Raines, S Parekh, O Jonas, JE Maggio, GR Strichartz Journal of pharmaceutical sciences 90 (9), 1407-1423, 2001 | 18 | 2001 |
In vivo detection of drug-induced apoptosis in tumors using Raman spectroscopy J WoongáKang, TC Peter Analyst 143 (20), 4836-4839, 2018 | 12 | 2018 |