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Scott A Peslak
Scott A Peslak
Assistant Professor of Medicine, University of Pennsylvania Perelman School of Medicine
Dirección de correo verificada de pennmedicine.upenn.edu
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Diagnosis and treatment of aplastic anemia
SA Peslak, T Olson, DV Babushok
Current treatment options in oncology 18, 1-20, 2017
1222017
EPO-mediated expansion of late-stage erythroid progenitors in the bone marrow initiates recovery from sublethal radiation stress
SA Peslak, J Wenger, JC Bemis, PD Kingsley, AD Koniski, KE McGrath, ...
Blood, The Journal of the American Society of Hematology 120 (12), 2501-2511, 2012
722012
Sublethal radiation injury uncovers a functional transition during erythroid maturation
SA Peslak, J Wenger, JC Bemis, PD Kingsley, JM Frame, AD Koniski, ...
Experimental hematology 39 (4), 434-445, 2011
572011
The HRI-regulated transcription factor ATF4 activates BCL11A transcription to silence fetal hemoglobin expression
P Huang, SA Peslak, X Lan, E Khandros, JA Yano, M Sharma, CA Keller, ...
Blood, The Journal of the American Society of Hematology 135 (24), 2121-2132, 2020
512020
The E3 ligase adaptor molecule SPOP regulates fetal hemoglobin levels in adult erythroid cells
X Lan, E Khandros, P Huang, SA Peslak, SK Bhardwaj, JD Grevet, ...
Blood Advances 3 (10), 1586-1597, 2019
312019
Understanding heterogeneity of fetal hemoglobin induction through comparative analysis of F and A erythroblasts
E Khandros, P Huang, SA Peslak, M Sharma, O Abdulmalik, BM Giardine, ...
Blood, The Journal of the American Society of Hematology 135 (22), 1957-1968, 2020
302020
Stochastic modeling of stress erythropoiesis using a two-type age-dependent branching process with immigration
O Hyrien, SA Peslak, NM Yanev, J Palis
Journal of mathematical biology 70, 1485-1521, 2015
212015
Peroxisome proliferator-activated receptor gamma overexpression and knockdown: impact on human B cell lymphoma proliferation and survival
TM Garcia-Bates, SA Peslak, CJ Baglole, SB Maggirwar, SH Bernstein, ...
Cancer immunology, immunotherapy 58, 1071-1083, 2009
212009
HIC2 controls developmental hemoglobin switching by repressing BCL11A transcription
P Huang, SA Peslak, R Ren, E Khandros, K Qin, CA Keller, B Giardine, ...
Nature genetics 54 (9), 1417-1426, 2022
182022
Dual function NFI factors control fetal hemoglobin silencing in adult erythroid cells
K Qin, P Huang, R Feng, CA Keller, SA Peslak, E Khandros, MS Saari, ...
Nature genetics 54 (6), 874-884, 2022
172022
HRI depletion cooperates with pharmacologic inducers to elevate fetal hemoglobin and reduce sickle cell formation
SA Peslak, E Khandros, P Huang, X Lan, CL Geronimo, JD Grevet, ...
Blood Advances 4 (18), 4560-4572, 2020
162020
Targeting the EIF2AK1 Signaling Pathway Rescues Red Blood Cell Production in SF3B1-Mutant Myelodysplastic Syndromes With Ringed Sideroblasts
V Adema, F Ma, R Kanagal-Shamanna, N Thongon, G Montalban-Bravo, ...
Blood cancer discovery 3 (6), 554-567, 2022
92022
Histone H2A. X phosphorylation and Caspase-Initiated Chromatin Condensation in late-stage erythropoiesis
NN Jeffery, C Davidson, SA Peslak, PD Kingsley, Y Nakamura, J Palis, ...
Epigenetics & Chromatin 14, 1-15, 2021
92021
Identification and characterization of RBM12 as a novel regulator of fetal hemoglobin expression
A Wakabayashi, M Kihiu, M Sharma, AJ Thrasher, MS Saari, ...
Blood Advances 6 (23), 5956-5968, 2022
62022
Hemoglobinopathies and thalassemias
S Peslak, F Sayani
Emery and Rimoin's Principles and Practice of Medical Genetics and Genomics …, 2023
32023
Forced enhancer-promoter rewiring to alter gene expression in animal models
SA Peslak, S Demirci, V Chandra, B Ryu, SK Bhardwaj, J Jiang, ...
Molecular Therapy-Nucleic Acids 31, 452-465, 2023
22023
Regulation of Fetal Hemoglobin Production in Adult Erythroid Cells By Protein Phosphatase 6C (PPP6C)
SA Peslak, E Khandros, P Huang, A Wakabayashi, T Abbas, ...
Blood 140 (Supplement 1), 2502-2503, 2022
22022
A novel, effective, and efficient strategy for treating sickle cell vaso-occlusive events in the infusion center setting
SA Peslak, AB Akins, AM Foxwell, M Iannelli, C Grande, D Breen, ...
Blood Advances 7 (3), 410-413, 2023
12023
Protein phosphatase 6c (PPP6C) loss significantly raises fetal hemoglobin levels and reduces cell sickling
SA Peslak, E Khandros, P Huang, M Kihiu, O Abdulmalik, CA Keller, ...
Blood 138, 2031, 2021
12021
Isolated changes in chromatin accessibility and enhancer-promoter contacts at the β-globin locus distinguish fetal hemoglobin producing F-cells from A-cells
E Khandros, P Huang, SA Peslak, M Sharma, O Abdulmalik, B Giardine, ...
Blood 138, 855, 2021
12021
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