|Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis|
K Shimada, TR Crother, J Karlin, J Dagvadorj, N Chiba, S Chen, ...
Immunity 36 (3), 401-414, 2012
|Lack of Toll-like receptor 4 or myeloid differentiation factor 88 reduces atherosclerosis and alters plaque phenotype in mice deficient in apolipoprotein E|
KS Michelsen, MH Wong, PK Shah, W Zhang, J Yano, TM Doherty, ...
Proceedings of the National Academy of Sciences 101 (29), 10679-10684, 2004
|Decreased expression of Toll-like receptor-4 and MD-2 correlates with intestinal epithelial cell protection against dysregulated proinflammatory gene expression in response to …|
MT Abreu, P Vora, E Faure, LS Thomas, ET Arnold, M Arditi
The Journal of Immunology 167 (3), 1609-1616, 2001
|Toll-like receptor-4 is expressed by macrophages in murine and human lipid-rich atherosclerotic plaques and upregulated by oxidized LDL|
XH Xu, PK Shah, E Faure, O Equils, L Thomas, MC Fishbein, D Luthringer, ...
Circulation 104 (25), 3103-3108, 2001
|TLR signaling in the gut in health and disease|
MT Abreu, M Fukata, M Arditi
The Journal of Immunology 174 (8), 4453-4460, 2005
|Bacterial lipopolysaccharide activates nuclear factor-κB through interleukin-1 signaling mediators in cultured human dermal endothelial cells and mononuclear phagocytes|
FX Zhang, CJ Kirschning, R Mancinelli, XP Xu, Y Jin, E Faure, ...
Journal of Biological Chemistry 274 (12), 7611-7614, 1999
|Bacterial lipopolysaccharide activates NF-κB through toll-like receptor 4 (TLR-4) in cultured human dermal endothelial cells differential expression of TLR-4 and TLR-2 in …|
E Faure, O Equils, PA Sieling, L Thomas, FX Zhang, CJ Kirschning, ...
Journal of Biological Chemistry 275 (15), 11058-11063, 2000
|Bacterial lipopolysaccharide and IFN-γ induce Toll-like receptor 2 and Toll-like receptor 4 expression in human endothelial cells: role of NF-κB activation|
E Faure, L Thomas, H Xu, AE Medvedev, O Equils, M Arditi
The Journal of Immunology 166 (3), 2018-2024, 2001
|Human intestinal epithelial cells are broadly unresponsive to Toll-like receptor 2-dependent bacterial ligands: implications for host-microbial interactions in the gut|
G Melmed, LS Thomas, N Lee, SY Tesfay, K Lukasek, KS Michelsen, ...
The Journal of Immunology 170 (3), 1406-1415, 2003
|Toll-like receptor-4 is required for intestinal response to epithelial injury and limiting bacterial translocation in a murine model of acute colitis|
M Fukata, KS Michelsen, R Eri, LS Thomas, B Hu, K Lukasek, CC Nast, ...
American Journal of Physiology-Gastrointestinal and Liver Physiology 288 (5 …, 2005
|Chlamydial heat shock protein 60 activates macrophages and endothelial cells through Toll-like receptor 4 and MD2 in a MyD88-dependent pathway|
Y Bulut, E Faure, L Thomas, H Karahashi, KS Michelsen, O Equils, ...
The Journal of Immunology 168 (3), 1435-1440, 2002
|TLR4 and MD-2 expression is regulated by immune-mediated signals in human intestinal epithelial cells|
MT Abreu, ET Arnold, LS Thomas, R Gonsky, Y Zhou, B Hu, M Arditi
Journal of Biological Chemistry 277 (23), 20431-20437, 2002
|Cooperation of Toll-like receptor 2 and 6 for cellular activation by soluble tuberculosis factor and Borrelia burgdorferi outer surface protein A lipoprotein: role of Toll …|
Y Bulut, E Faure, L Thomas, O Equils, M Arditi
The Journal of Immunology 167 (2), 987-994, 2001
|Cox-2 is regulated by Toll-like receptor-4 (TLR4) signaling: Role in proliferation and apoptosis in the intestine|
M Fukata, A Chen, A Klepper, S Krishnareddy, AS Vamadevan, ...
Gastroenterology 131 (3), 862-877, 2006
|β-defensin-2 expression is regulated by TLR signaling in intestinal epithelial cells|
P Vora, A Youdim, LS Thomas, M Fukata, SY Tesfay, K Lukasek, ...
The Journal of Immunology 173 (9), 5398-5405, 2004
|Three-year multicenter surveillance of pneumococcal meningitis in children: clinical characteristics, and outcome related to penicillin susceptibility and dexamethasone use|
M Arditi, EO Mason, JS Bradley, TQ Tan, WJ Barson, GE Schutze, ...
Pediatrics 102 (5), 1087-1097, 1998
|The roles of bacteria and TLR4 in rat and murine models of necrotizing enterocolitis|
T Jilling, D Simon, J Lu, FJ Meng, D Li, R Schy, RB Thomson, A Soliman, ...
The Journal of Immunology 177 (5), 3273-3282, 2006
|HMGB1 mediates endogenous TLR2 activation and brain tumor regression|
JF Curtin, N Liu, M Candolfi, W Xiong, H Assi, K Yagiz, MR Edwards, ...
PLoS Med 6 (1), e1000010, 2009
|Distinct Mutations in IRAK-4 Confer Hyporesponsiveness to Lipopolysaccharide and Interleukin-1 in a Patient with Recurrent Bacterial Infections|
AE Medvedev, A Lentschat, DB Kuhns, JCG Blanco, C Salkowski, ...
The Journal of experimental medicine 198 (4), 521-531, 2003
|TLR signaling: an emerging bridge from innate immunity to atherogenesis|
KS Michelsen, TM Doherty, PK Shah, M Arditi
The Journal of Immunology 173 (10), 5901-5907, 2004