A single-cell transcriptome atlas of the human pancreas MJ Muraro, G Dharmadhikari, D Grün, N Groen, T Dielen, E Jansen, ... Cell systems 3 (4), 385-394. e3, 2016 | 1061 | 2016 |
Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes MJL Kracht, M van Lummel, T Nikolic, AM Joosten, S Laban, ... Nature medicine 23 (4), 501-507, 2017 | 220 | 2017 |
Lentiviral vectors efficiently transduce quiescent mature 3T3-L1 adipocytes F Carlotti, M Bazuine, T Kekarainen, J Seppen, P Pognonec, JA Maassen, ... Molecular therapy 9 (2), 209-217, 2004 | 206 | 2004 |
Loss of β-cell identity occurs in type 2 diabetes and is associated with islet amyloid deposits HS Spijker, H Song, JH Ellenbroek, MM Roefs, MA Engelse, E Bos, ... Diabetes 64 (8), 2928-2938, 2015 | 190 | 2015 |
Conversion of mature human β-cells into glucagon-producing α-cells HS Spijker, RBG Ravelli, AM Mommaas-Kienhuis, AA van Apeldoorn, ... Diabetes 62 (7), 2471-2480, 2013 | 170 | 2013 |
Long-term ketogenic diet causes glucose intolerance and reduced β-and α-cell mass but no weight loss in mice JH Ellenbroek, L van Dijck, HA Töns, TJ Rabelink, F Carlotti, ... American Journal of Physiology-Endocrinology and Metabolism, 2014 | 165 | 2014 |
Expansion of adult human pancreatic tissue yields organoids harboring progenitor cells with endocrine differentiation potential CJM Loomans, NW Giuliani, J Balak, F Ringnalda, L van Gurp, M Huch, ... Stem Cell Reports 10 (3), 712-724, 2018 | 123 | 2018 |
KeyGenes, a tool to probe tissue differentiation using a human fetal transcriptional atlas MS Roost, L Van Iperen, Y Ariyurek, HP Buermans, W Arindrarto, ... Stem cell reports 4 (6), 1112-1124, 2015 | 123 | 2015 |
DNA damage in transcribed genes induces apoptosis via the JNK pathway and the JNK-phosphatase MKP-1 M Hamdi, J Kool, P Cornelissen-Steijger, F Carlotti, HE Popeijus, ... Oncogene 24 (48), 7135-7144, 2005 | 103 | 2005 |
The CTRB1/2 Locus Affects Diabetes Susceptibility and Treatment via the Incretin Pathway LM ‘t Hart, A Fritsche, G Nijpels, N van Leeuwen, LA Donnelly, JM Dekker, ... Diabetes 62 (9), 3275-3281, 2013 | 99 | 2013 |
DNA methylation landscapes of human fetal development RC Slieker, MS Roost, L van Iperen, HED Suchiman, EW Tobi, F Carlotti, ... PLoS genetics 11 (10), e1005583, 2015 | 97 | 2015 |
Isolated human islets contain a distinct population of mesenchymal stem cells F Carlotti, A Zaldumbide, CJ Loomans, E van Rossenberg, M Engelse, ... Islets 2 (3), 164-173, 2010 | 91 | 2010 |
Controlled aggregation of primary human pancreatic islet cells leads to glucose‐responsive pseudoislets comparable to native islets J Hilderink, S Spijker, F Carlotti, L Lange, M Engelse, C van Blitterswijk, ... Journal of cellular and molecular medicine 19 (8), 1836-1846, 2015 | 90 | 2015 |
Mitogen-activated protein kinase (MAPK) phosphatase-1 and-4 attenuate p38 MAPK during dexamethasone-induced insulin resistance in 3T3-L1 adipocytes M Bazuine, F Carlotti, RSJ Tafrechi, RC Hoeben, JA Maassen Molecular endocrinology 18 (7), 1697-1707, 2004 | 81 | 2004 |
Bcl-XL expression correlates with primary macrophage differentiation, activation of functional competence, and survival and results from synergistic transcriptional activation … L Sevilla, A Zaldumbide, F Carlotti, MA Dayem, P Pognonec, KE Boulukos Journal of Biological Chemistry 276 (21), 17800-17807, 2001 | 75 | 2001 |
Mesenchymal stem cells or cardiac progenitors for cardiac repair? A comparative study R Koninckx, A Daniëls, S Windmolders, F Carlotti, U Mees, P Steels, ... Cellular and Molecular Life Sciences 68, 2141-2156, 2011 | 72 | 2011 |
Oxidative stress leads to β-cell dysfunction through loss of β-cell identity F Leenders, N Groen, N de Graaf, MA Engelse, TJ Rabelink, ... Frontiers in immunology 12, 690379, 2021 | 61 | 2021 |
ATF3 and Fra1 have opposite functions in JNK-and ERK-dependent DNA damage responses M Hamdi, HE Popeijus, F Carlotti, JM Janssen, C van der Burgt, ... DNA repair 7 (3), 487-496, 2008 | 60 | 2008 |
DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells MS Roost, RC Slieker, M Bialecka, L Van Iperen, MM Gomes Fernandes, ... Nature Communications 8 (1), 908, 2017 | 58 | 2017 |
Topologically heterogeneous beta cell adaptation in response to high-fat diet in mice JH Ellenbroek, HA Töns, N de Graaf, CJ Loomans, MA Engelse, H Vrolijk, ... PLoS One 8 (2), e56922, 2013 | 56 | 2013 |