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Françoise Carlotti
Françoise Carlotti
Associate Professor, Leiden University Medical Center
Dirección de correo verificada de lumc.nl
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A single-cell transcriptome atlas of the human pancreas
MJ Muraro, G Dharmadhikari, D Grün, N Groen, T Dielen, E Jansen, ...
Cell systems 3 (4), 385-394. e3, 2016
10612016
Autoimmunity against a defective ribosomal insulin gene product in type 1 diabetes
MJL Kracht, M van Lummel, T Nikolic, AM Joosten, S Laban, ...
Nature medicine 23 (4), 501-507, 2017
2202017
Lentiviral vectors efficiently transduce quiescent mature 3T3-L1 adipocytes
F Carlotti, M Bazuine, T Kekarainen, J Seppen, P Pognonec, JA Maassen, ...
Molecular therapy 9 (2), 209-217, 2004
2062004
Loss of β-cell identity occurs in type 2 diabetes and is associated with islet amyloid deposits
HS Spijker, H Song, JH Ellenbroek, MM Roefs, MA Engelse, E Bos, ...
Diabetes 64 (8), 2928-2938, 2015
1902015
Conversion of mature human β-cells into glucagon-producing α-cells
HS Spijker, RBG Ravelli, AM Mommaas-Kienhuis, AA van Apeldoorn, ...
Diabetes 62 (7), 2471-2480, 2013
1702013
Long-term ketogenic diet causes glucose intolerance and reduced β-and α-cell mass but no weight loss in mice
JH Ellenbroek, L van Dijck, HA Töns, TJ Rabelink, F Carlotti, ...
American Journal of Physiology-Endocrinology and Metabolism, 2014
1652014
Expansion of adult human pancreatic tissue yields organoids harboring progenitor cells with endocrine differentiation potential
CJM Loomans, NW Giuliani, J Balak, F Ringnalda, L van Gurp, M Huch, ...
Stem Cell Reports 10 (3), 712-724, 2018
1232018
KeyGenes, a tool to probe tissue differentiation using a human fetal transcriptional atlas
MS Roost, L Van Iperen, Y Ariyurek, HP Buermans, W Arindrarto, ...
Stem cell reports 4 (6), 1112-1124, 2015
1232015
DNA damage in transcribed genes induces apoptosis via the JNK pathway and the JNK-phosphatase MKP-1
M Hamdi, J Kool, P Cornelissen-Steijger, F Carlotti, HE Popeijus, ...
Oncogene 24 (48), 7135-7144, 2005
1032005
The CTRB1/2 Locus Affects Diabetes Susceptibility and Treatment via the Incretin Pathway
LM ‘t Hart, A Fritsche, G Nijpels, N van Leeuwen, LA Donnelly, JM Dekker, ...
Diabetes 62 (9), 3275-3281, 2013
992013
DNA methylation landscapes of human fetal development
RC Slieker, MS Roost, L van Iperen, HED Suchiman, EW Tobi, F Carlotti, ...
PLoS genetics 11 (10), e1005583, 2015
972015
Isolated human islets contain a distinct population of mesenchymal stem cells
F Carlotti, A Zaldumbide, CJ Loomans, E van Rossenberg, M Engelse, ...
Islets 2 (3), 164-173, 2010
912010
Controlled aggregation of primary human pancreatic islet cells leads to glucose‐responsive pseudoislets comparable to native islets
J Hilderink, S Spijker, F Carlotti, L Lange, M Engelse, C van Blitterswijk, ...
Journal of cellular and molecular medicine 19 (8), 1836-1846, 2015
902015
Mitogen-activated protein kinase (MAPK) phosphatase-1 and-4 attenuate p38 MAPK during dexamethasone-induced insulin resistance in 3T3-L1 adipocytes
M Bazuine, F Carlotti, RSJ Tafrechi, RC Hoeben, JA Maassen
Molecular endocrinology 18 (7), 1697-1707, 2004
812004
Bcl-XL expression correlates with primary macrophage differentiation, activation of functional competence, and survival and results from synergistic transcriptional activation …
L Sevilla, A Zaldumbide, F Carlotti, MA Dayem, P Pognonec, KE Boulukos
Journal of Biological Chemistry 276 (21), 17800-17807, 2001
752001
Mesenchymal stem cells or cardiac progenitors for cardiac repair? A comparative study
R Koninckx, A Daniëls, S Windmolders, F Carlotti, U Mees, P Steels, ...
Cellular and Molecular Life Sciences 68, 2141-2156, 2011
722011
Oxidative stress leads to β-cell dysfunction through loss of β-cell identity
F Leenders, N Groen, N de Graaf, MA Engelse, TJ Rabelink, ...
Frontiers in immunology 12, 690379, 2021
612021
ATF3 and Fra1 have opposite functions in JNK-and ERK-dependent DNA damage responses
M Hamdi, HE Popeijus, F Carlotti, JM Janssen, C van der Burgt, ...
DNA repair 7 (3), 487-496, 2008
602008
DNA methylation and transcriptional trajectories during human development and reprogramming of isogenic pluripotent stem cells
MS Roost, RC Slieker, M Bialecka, L Van Iperen, MM Gomes Fernandes, ...
Nature Communications 8 (1), 908, 2017
582017
Topologically heterogeneous beta cell adaptation in response to high-fat diet in mice
JH Ellenbroek, HA Töns, N de Graaf, CJ Loomans, MA Engelse, H Vrolijk, ...
PLoS One 8 (2), e56922, 2013
562013
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