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Shyamala Maheswaran
Shyamala Maheswaran
Harvard Medical School
Dirección de correo verificada de helix.mgh.harvard.edu
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Isolation of rare circulating tumour cells in cancer patients by microchip technology
S Nagrath, LV Sequist, S Maheswaran, DW Bell, D Irimia, L Ulkus, ...
Nature 450 (7173), 1235-1239, 2007
44072007
Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition
M Yu, A Bardia, BS Wittner, SL Stott, ME Smas, DT Ting, SJ Isakoff, ...
science 339 (6119), 580-584, 2013
26432013
A chromatin-mediated reversible drug-tolerant state in cancer cell subpopulations
SV Sharma, DY Lee, B Li, MP Quinlan, F Takahashi, S Maheswaran, ...
Cell 141 (1), 69-80, 2010
26262010
Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis
N Aceto, A Bardia, DT Miyamoto, MC Donaldson, BS Wittner, JA Spencer, ...
Cell 158 (5), 1110-1122, 2014
24492014
Detection of Mutations in EGFR in Circulating Lung-Cancer Cells
S Maheswaran, LV Sequist, S Nagrath, L Ulkus, B Brannigan, CV Collura, ...
New England Journal of Medicine 359 (4), 366-377, 2008
21272008
Isolation of circulating tumor cells using a microvortex-generating herringbone-chip
SL Stott, CH Hsu, DI Tsukrov, M Yu, DT Miyamoto, BA Waltman, ...
Proceedings of the National Academy of Sciences 107 (43), 18392-18397, 2010
19662010
Circulating tumor cells: approaches to isolation and characterization
M Yu, S Stott, M Toner, S Maheswaran, DA Haber
Journal of Cell Biology 192 (3), 373-382, 2011
13182011
Inertial focusing for tumor antigen–dependent and–independent sorting of rare circulating tumor cells
E Ozkumur, AM Shah, JC Ciciliano, BL Emmink, DT Miyamoto, E Brachtel, ...
Science translational medicine 5 (179), 179ra47-179ra47, 2013
11952013
Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility
M Yu, A Bardia, N Aceto, F Bersani, MW Madden, MC Donaldson, ...
science 345 (6193), 216-220, 2014
9782014
Microfluidic, marker-free isolation of circulating tumor cells from blood samples
NM Karabacak, PS Spuhler, F Fachin, EJ Lim, V Pai, E Ozkumur, ...
Nature protocols 9 (3), 694-710, 2014
8022014
Induction of GADD45 and JNK/SAPK-dependent apoptosis following inducible expression of BRCA1
DP Harkin, JM Bean, D Miklos, YH Song, VB Truong, C Englert, ...
Cell 97 (5), 575-586, 1999
7491999
A microfluidic device for label-free, physical capture of circulating tumor cell clusters
AF Sarioglu, N Aceto, N Kojic, MC Donaldson, M Zeinali, B Hamza, ...
Nature methods 12 (7), 685-691, 2015
7352015
RNA-Seq of single prostate CTCs implicates noncanonical Wnt signaling in antiandrogen resistance
DT Miyamoto, Y Zheng, BS Wittner, RJ Lee, H Zhu, KT Broderick, R Desai, ...
Science 349 (6254), 1351-1356, 2015
7102015
Isolation and characterization of circulating tumor cells from patients with localized and metastatic prostate cancer
SL Stott, RJ Lee, S Nagrath, M Yu, DT Miyamoto, L Ulkus, EJ Inserra, ...
Science translational medicine 2 (25), 25ra23-25ra23, 2010
6452010
Aberrant overexpression of satellite repeats in pancreatic and other epithelial cancers
DT Ting, D Lipson, S Paul, BW Brannigan, S Akhavanfard, EJ Coffman, ...
science 331 (6017), 593-596, 2011
5762011
RNA sequencing of pancreatic circulating tumour cells implicates WNT signalling in metastasis
M Yu, DT Ting, SL Stott, BS Wittner, F Ozsolak, S Paul, JC Ciciliano, ...
Nature 487 (7408), 510-513, 2012
5662012
Single-cell RNA sequencing identifies extracellular matrix gene expression by pancreatic circulating tumor cells
DT Ting, BS Wittner, M Ligorio, NV Jordan, AM Shah, DT Miyamoto, ...
Cell reports 8 (6), 1905-1918, 2014
5102014
Genomic alterations of anaplastic lymphoma kinase may sensitize tumors to anaplastic lymphoma kinase inhibitors
U McDermott, AJ Iafrate, NS Gray, T Shioda, M Classon, S Maheswaran, ...
Cancer research 68 (9), 3389-3395, 2008
5062008
Clusters of circulating tumor cells traverse capillary-sized vessels
SH Au, BD Storey, JC Moore, Q Tang, YL Chen, S Javaid, AF Sarioglu, ...
Proceedings of the National Academy of Sciences 113 (18), 4947-4952, 2016
4672016
Stromal microenvironment shapes the intratumoral architecture of pancreatic cancer
M Ligorio, S Sil, J Malagon-Lopez, LT Nieman, S Misale, M Di Pilato, ...
Cell 178 (1), 160-175. e27, 2019
4412019
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Artículos 1–20