Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice J Vincent, C Adura, P Gao, A Luz, L Lama, Y Asano, R Okamoto, ... Nature communications 8 (1), 750, 2017 | 248 | 2017 |
Development of human cGAS-specific small-molecule inhibitors for repression of dsDNA-triggered interferon expression L Lama, C Adura, W Xie, D Tomita, T Kamei, V Kuryavyi, T Gogakos, ... Nature Communications 10 (1), 2261, 2019 | 158 | 2019 |
Improving the brain delivery of gold nanoparticles by conjugation with an amphipathic peptide S Guerrero, E Araya, JL Fiedler, JI Arias, C Adura, F Albericio, E Giralt, ... Nanomedicine 5 (6), 897-913, 2010 | 152 | 2010 |
Human cGAS catalytic domain has an additional DNA-binding interface that enhances enzymatic activity and liquid-phase condensation W Xie, L Lama, C Adura, D Tomita, JF Glickman, T Tuschl, DJ Patel Proceedings of the National Academy of Sciences 116 (24), 11946-11955, 2019 | 142 | 2019 |
Small-molecule targeting of MUSASHI RNA-binding activity in acute myeloid leukemia G Minuesa, SK Albanese, W Xie, Y Kazansky, D Worroll, A Chow, ... Nature communications 10 (1), 2691, 2019 | 116 | 2019 |
Stable conjugates of peptides with gold nanorods for biomedical applications with reduced effects on cell viability C Adura, S Guerrero, E Salas, L Medel, A Riveros, J Mena, J Arbiol, ... ACS applied materials & interfaces 5 (10), 4076-4085, 2013 | 94 | 2013 |
Discovery of LRE1 as a specific and allosteric inhibitor of soluble adenylyl cyclase L Ramos-Espiritu, S Kleinboelting, FA Navarrete, A Alvau, PE Visconti, ... Nature chemical biology 12 (10), 838-844, 2016 | 86 | 2016 |
Reconstitution of a Mycobacterium tuberculosis proteostasis network highlights essential cofactor interactions with chaperone DnaK TJ Lupoli, A Fay, C Adura, MS Glickman, CF Nathan Proceedings of the National Academy of Sciences 113 (49), E7947-E7956, 2016 | 46 | 2016 |
Carbon Nanotubes Electrochemistry Allows the In Situ Evaluation of the Effect of β‐Sheet Breakers on the Aggregation Process of β‐Amyloid E De La Fuente, C Adura, MJ Kogan, S Bollo Electroanalysis 24 (4), 938-944, 2012 | 17 | 2012 |
Improving cell penetration of gold nanorods by using an amphipathic arginine rich peptide AL Riveros, C Eggeling, S Riquelme, C Adura, C López-Iglesias, ... International Journal of Nanomedicine, 1837-1851, 2020 | 15 | 2020 |
Conformation‐specific antibodies against multiple amyloid protofibril species from a single amyloid immunogen A Bonito‐Oliva, S Schedin‐Weiss, SS Younesi, A Tiiman, C Adura, ... Journal of Cellular and Molecular Medicine 23 (3), 2103-2114, 2019 | 14 | 2019 |
Small molecule inhibition of cGAS reduces interferon expression in primary macrophages from autoimmune mice. Nat Commun 8: 750 J Vincent, C Adura, P Gao, A Luz, L Lama, Y Asano, R Okamoto, ... | 14 | 2017 |
An allosteric inhibitor of bacterial Hsp70 chaperone potentiates antibiotics and mitigates resistance J Hosfelt, A Richards, M Zheng, C Adura, B Nelson, A Yang, A Fay, ... Cell chemical biology 29 (5), 854-869. e9, 2022 | 12 | 2022 |
Ion pair method to determine the CTAB content in gold nanorods samples C Adura, F Guzman, A Alvarez-Lueje, MJ Kogan Journal of the Chilean Chemical Society 59 (4), 2701-2704, 2014 | 12 | 2014 |
Selective nanodecoration of modified cyclodextrin crystals with gold nanorods B Herrera, C Adura, N Yutronic, MJ Kogan, P Jara Journal of colloid and interface science 389 (1), 42-45, 2013 | 11 | 2013 |
A histone-like motif in yellow fever virus contributes to viral replication D Mourão, S Chen, U Schaefer, L Bozzacco, LA Carneiro, A Gerber, ... Biorxiv, 2020.05. 05.078782, 2020 | 6 | 2020 |
Sindbis Macrodomain Poly-ADP-Ribose Hydrolase Activity Is Important for Viral RNA Synthesis EG Aguilar, G Paniccia, C Adura, ZS Singer, AW Ashbrook, BS Razooky, ... Journal of Virology 96 (7), e01516-21, 2022 | 5 | 2022 |
Small-Molecule Targeting of Musashi RNA-Binding Activity in Acute Myeloid Leukemia G Minuesa Dinares, SK Albanese, A Chow, A Schurer, SM Park, ... Blood 132 (Supplement 1), 428-428, 2018 | 1 | 2018 |
Lead Optimization of Small Molecule ENL YEATS Inhibitors to Enable In Vivo Studies: Discovery of TDI-11055 M Michino, TA Khan, MW Miller, Y Fukase, J Vendome, C Adura, ... ACS Medicinal Chemistry Letters 15 (4), 524-532, 2024 | | 2024 |
High-throughput screening identifies small molecule inhibitors of thioesterase superfamily member 1: Implications for the management of non-alcoholic fatty liver disease CS Krumm, RS Landzberg, L Ramos-Espiritu, C Adura, X Liu, M Acuna, ... Molecular Metabolism 78, 101832, 2023 | | 2023 |