Shangzhong Li
Shangzhong Li
Senior Scientist, BMS
Verified email at
Cited by
Cited by
Recon 2.2: from reconstruction to model of human metabolism
N Swainston, K Smallbone, H Hefzi, PD Dobson, J Brewer, M Hanscho, ...
Metabolomics 12, 1-7, 2016
Rapid neurogenesis through transcriptional activation in human stem cells
V Busskamp, NE Lewis, P Guye, AHM Ng, SL Shipman, SM Byrne, ...
Molecular systems biology 10 (11), 760, 2014
A consensus genome-scale reconstruction of Chinese hamster ovary cell metabolism
H Hefzi, KS Ang, M Hanscho, A Bordbar, D Ruckerbauer, M Lakshmanan, ...
Cell systems 3 (5), 434-443. e8, 2016
A systematic evaluation of methods for tailoring genome-scale metabolic models
S Opdam, A Richelle, B Kellman, S Li, DC Zielinski, NE Lewis
Cell systems 4 (3), 318-329. e6, 2017
A reference genome of the Chinese hamster based on a hybrid assembly strategy
O Rupp, ML MacDonald, S Li, H Dhiman, S Polson, S Griep, K Heffner, ...
Biotechnology and bioengineering 115 (8), 2087-2100, 2018
Genome-scale reconstructions of the mammalian secretory pathway predict metabolic costs and limitations of protein secretion
JM Gutierrez, A Feizi, S Li, TB Kallehauge, H Hefzi, LM Grav, D Ley, ...
Nature communications 11 (1), 68, 2020
Ribosome profiling-guided depletion of an mRNA increases cell growth rate and protein secretion
TB Kallehauge, S Li, LE Pedersen, TK Ha, D Ley, MR Andersen, ...
Scientific reports 7 (1), 40388, 2017
An excitatory circuit in the perioculomotor midbrain for non-REM sleep control
Z Zhang, P Zhong, F Hu, Z Barger, Y Ren, X Ding, S Li, F Weber, S Chung, ...
Cell 177 (5), 1293-1307. e16, 2019
Quantitative feature extraction from the Chinese hamster ovary bioprocess bibliome using a novel meta-analysis workflow
A Golabgir, JM Gutierrez, H Hefzi, S Li, BO Palsson, C Herwig, NE Lewis
Biotechnology advances 34 (5), 621-633, 2016
Reduced apoptosis in Chinese hamster ovary cells via optimized CRISPR interference
K Xiong, KF Marquart, KJ la Cour Karottki, S Li, I Shamie, JS Lee, ...
Biotechnology and bioengineering 116 (7), 1813-1819, 2019
Dual RNA-seq identifies human mucosal immunity protein Mucin-13 as a hallmark of Plasmodium exoerythrocytic infection
GM LaMonte, P Orjuela-Sanchez, J Calla, LT Wang, S Li, J Swann, ...
Nature communications 10 (1), 488, 2019
Awakening dormant glycosyltransferases in CHO cells with CRISPRa
KJC Karottki, H Hefzi, K Xiong, I Shamie, AH Hansen, S Li, LE Pedersen, ...
Biotechnology and bioengineering 117 (2), 593-598, 2020
Whole-genome sequencing of invasion-resistant cells identifies laminin α2 as a host factor for bacterial invasion
XM Van Wijk, S Döhrmann, BM Hallström, S Li, BG Voldborg, BX Meng, ...
MBio 8 (1), 10.1128/mbio. 02128-16, 2017
Model-based assessment of mammalian cell metabolic functionalities using omics data
A Richelle, BP Kellman, AT Wenzel, AWT Chiang, T Reagan, ...
Cell reports methods 1 (3), 2021
Modulating carbohydrate–protein interactions through glycoengineering of monoclonal antibodies to impact cancer physiology
AWT Chiang, S Li, PN Spahn, A Richelle, CC Kuo, M Samoudi, NE Lewis
Current opinion in structural biology 40, 104-111, 2016
Multiple freeze-thaw cycles lead to a loss of consistency in poly (A)-enriched RNA sequencing
BP Kellman, HM Baghdassarian, T Pramparo, I Shamie, V Gazestani, ...
BMC genomics 22, 1-15, 2021
An optimized genome-wide, virus-free CRISPR screen for mammalian cells
K Xiong, KJ la Cour Karottki, H Hefzi, S Li, LM Grav, S Li, P Spahn, JS Lee, ...
Cell Reports Methods 1 (4), 2021
Restoration of DNA repair mitigates genome instability and increases productivity of Chinese hamster ovary cells
PN Spahn, X Zhang, Q Hu, H Lu, NK Hamaker, H Hefzi, S Li, CC Kuo, ...
Biotechnology and bioengineering 119 (3), 963-982, 2022
Proteogenomic annotation of Chinese hamsters reveals extensive novel translation events and endogenous retroviral elements
S Li, SW Cha, K Heffner, DB Hizal, MA Bowen, R Chaerkady, RN Cole, ...
Journal of proteome research 18 (6), 2433-2445, 2019
Combating viral contaminants in CHO cells by engineering innate immunity
AWT Chiang, S Li, BP Kellman, G Chattopadhyay, Y Zhang, CC Kuo, ...
Scientific reports 9 (1), 8827, 2019
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Articles 1–20