| The pivotal role of the complement system in aging and age-related macular degeneration: hypothesis re-visited DH Anderson, MJ Radeke, NB Gallo, EA Chapin, PT Johnson, CR Curletti, ... Progress in retinal and eye research 29 (2), 95-112, 2010 | 833 | 2010 |
| Reticular pseudodrusen are subretinal drusenoid deposits SA Zweifel, RF Spaide, CA Curcio, G Malek, Y Imamura Ophthalmology 117 (2), 303-312. e1, 2010 | 483 | 2010 |
| Apolipoprotein E allele-dependent pathogenesis: a model for age-related retinal degeneration G Malek, LV Johnson, BE Mace, P Saloupis, DE Schmechel, DW Rickman, ... Proceedings of the National Academy of Sciences 102 (33), 11900-11905, 2005 | 326 | 2005 |
| Esterified and unesterified cholesterol in drusen and basal deposits of eyes with age-related maculopathy CA Curcio, JB Presley, G Malek, NE Medeiros, DV Avery, HS Kruth Experimental eye research 81 (6), 731-741, 2005 | 285 | 2005 |
| Apolipoprotein B in cholesterol-containing drusen and basal deposits of human eyes with age-related maculopathy G Malek, CM Li, C Guidry, NE Medeiros, CA Curcio The American journal of pathology 162 (2), 413-425, 2003 | 285 | 2003 |
| Sub-retinal drusenoid deposits in human retina: organization and composition M Rudolf, G Malek, JD Messinger, ME Clark, L Wang, CA Curcio Experimental eye research 87 (5), 402-408, 2008 | 215 | 2008 |
| Peripapillary chorioretinal atrophy: Bruch’s membrane changes and photoreceptor loss CA Curcio, PL Saunders, PW Younger, G Malek Ophthalmology 107 (2), 334-343, 2000 | 164 | 2000 |
| Lipoprotein-like particles and cholesteryl esters in human Bruch’s membrane: initial characterization CM Li, BH Chung, JB Presley, G Malek, X Zhang, N Dashti, L Li, J Chen, ... Investigative ophthalmology & visual science 46 (7), 2576-2586, 2005 | 162 | 2005 |
| Molecular genetics of AMD and current animal models AO Edwards, G Malek Angiogenesis 10, 119-132, 2007 | 108 | 2007 |
| Dominant late-onset retinal degeneration with regional variation of sub-retinal pigment epithelium deposits, retinal function, and photoreceptor degeneration AH Milam, CA Curcio, AV Cideciyan, S Saxena, SK John, HS Kruth, ... Ophthalmology 107 (12), 2256-2266, 2000 | 100 | 2000 |
| Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology P Hu, R Herrmann, A Bednar, P Saloupis, MA Dwyer, P Yang, X Qi, ... Proceedings of the National Academy of Sciences 110 (43), E4069-E4078, 2013 | 93 | 2013 |
| Insulin-like growth factor-1 contributes to neovascularization in age-related macular degeneration R Rosenthal, H Wohlleben, G Malek, L Schlichting, H Thieme, ... Biochemical and biophysical research communications 323 (4), 1203-1208, 2004 | 74 | 2004 |
| The fibroblast growth factor receptors, FGFR-1 and FGFR-2, mediate two independent signalling pathways in human retinal pigment epithelial cells R Rosenthal, G Malek, N Salomon, M Peill-Meininghaus, L Coeppicus, ... Biochemical and biophysical research communications 337 (1), 241-247, 2005 | 73 | 2005 |
| Age-related macular degeneration revisited: From pathology and cellular stress to potential therapies M Hadziahmetovic, G Malek Frontiers in cell and developmental biology 8, 612812, 2021 | 72 | 2021 |
| Research resource: nuclear receptor atlas of human retinal pigment epithelial cells: potential relevance to age-related macular degeneration MA Dwyer, D Kazmin, P Hu, DP McDonnell, G Malek Molecular endocrinology 25 (2), 360-372, 2011 | 65 | 2011 |
| The mechanism of diabetic retinopathy pathogenesis unifying key lipid regulators, sirtuin 1 and liver X receptor SS Hammer, E Beli, N Kady, Q Wang, K Wood, TA Lydic, G Malek, ... EBioMedicine 22, 181-190, 2017 | 55 | 2017 |
| Impaired monocyte cholesterol clearance initiates age-related retinal degeneration and vision loss N Ban, TJ Lee, A Sene, M Choudhary, M Lekwuwa, Z Dong, A Santeford, ... JCI insight 3 (17), 2018 | 53 | 2018 |
| Aryl hydrocarbon receptor knock‐out exacerbates choroidal neovascularization via multiple pathogenic pathways M Choudhary, D Kazmin, P Hu, RS Thomas, DP McDonnell, G Malek The Journal of pathology 235 (1), 101-112, 2015 | 53 | 2015 |
| Emerging roles for nuclear receptors in the pathogenesis of age-related macular degeneration G Malek, EM Lad Cellular and molecular life sciences 71, 4617-4636, 2014 | 53 | 2014 |
| Models of retinal diseases and their applicability in drug discovery G Malek, J Busik, MB Grant, M Choudhary Expert opinion on drug discovery 13 (4), 359-377, 2018 | 43 | 2018 |
