Marine natural products: a new wave of drugs? R Montaser, H Luesch Future medicinal chemistry 3 (12), 1475-1489, 2011 | 617 | 2011 |
Structure and Activity of Largazole, a Potent Antiproliferative Agent from the Floridian Marine Cyanobacterium Symploca sp. K Taori, VJ Paul, H Luesch Journal of the American Chemical Society 130 (6), 1806-1807, 2008 | 528 | 2008 |
Isolation of Dolastatin 10 from the Marine Cyanobacterium Symploca Species VP642 and Total Stereochemistry and Biological Evaluation of Its Analogue … H Luesch, RE Moore, VJ Paul, SL Mooberry, TH Corbett Journal of Natural Products 64 (7), 907-910, 2001 | 501 | 2001 |
Total Structure Determination of Apratoxin A, a Potent Novel Cytotoxin from the Marine Cyanobacterium Lyngbya majuscula H Luesch, WY Yoshida, RE Moore, VJ Paul, TH Corbett Journal of the American Chemical Society 123 (23), 5418-5423, 2001 | 465 | 2001 |
Total synthesis and molecular target of largazole, a histone deacetylase inhibitor Y Ying, K Taori, H Kim, J Hong, H Luesch Journal of the American Chemical Society 130 (26), 8455-8459, 2008 | 261 | 2008 |
Telomere-independent Rap1 is an IKK adaptor and regulates NF-κB-dependent gene expression H Teo, S Ghosh, H Luesch, A Ghosh, ET Wong, N Malik, A Orth, ... Nature cell biology 12 (8), 758-767, 2010 | 244 | 2010 |
Isolation, Structure Determination, and Biological Activity of Lyngbyabellin A from the Marine Cyanobacterium Lyngbya majuscula H Luesch, WY Yoshida, RE Moore, VJ Paul, SL Mooberry Journal of natural products 63 (5), 611-615, 2000 | 238 | 2000 |
A genomic screen for activators of the antioxidant response element Y Liu, JT Kern, JR Walker, JA Johnson, PG Schultz, H Luesch Proceedings of the National Academy of Sciences 104 (12), 5205-5210, 2007 | 220 | 2007 |
New apratoxins of marine cyanobacterial origin from Guam and Palau H Luesch, WY Yoshida, RE Moore, VJ Paul Bioorganic & medicinal chemistry 10 (6), 1973-1978, 2002 | 211 | 2002 |
Symplostatin 1: A Dolastatin 10 Analogue from the Marine Cyanobacterium Symploca hydnoides GG Harrigan, H Luesch, WY Yoshida, RE Moore, DG Nagle, VJ Paul, ... Journal of natural products 61 (9), 1075-1077, 1998 | 206 | 1998 |
Largazole: From discovery to broad-spectrum therapy J Hong, H Luesch Natural product reports 29 (4), 449-456, 2012 | 196 | 2012 |
A functional genomics approach to the mode of action of apratoxin A H Luesch, SK Chanda, RM Raya, PD DeJesus, AP Orth, JR Walker, ... Nature chemical biology 2 (3), 158-167, 2006 | 192 | 2006 |
The cyanobacterial origin of potent anticancer agents originally isolated from sea hares H Luesch, GG Harrigan, G Goetz, FD Horgen Current medicinal chemistry 9 (20), 1791-1806, 2002 | 180 | 2002 |
Biological targets and mechanisms of action of natural products from marine cyanobacteria LA Salvador-Reyes, H Luesch Natural product reports 32 (3), 478-503, 2015 | 170 | 2015 |
Apratoxin E, a Cytotoxic Peptolide from a Guamanian Collection of the Marine Cyanobacterium Lyngbya bouillonii S Matthew, PJ Schupp, H Luesch Journal of natural products 71 (6), 1113-1116, 2008 | 160 | 2008 |
Apratoxin a reversibly inhibits the secretory pathway by preventing cotranslational translocation Y Liu, BK Law, H Luesch Molecular pharmacology 76 (1), 91-104, 2009 | 158 | 2009 |
Seaweed extracts and unsaturated fatty acid constituents from the green alga Ulva lactuca as activators of the cytoprotective Nrf2–ARE pathway R Wang, VJ Paul, H Luesch Free Radical Biology and Medicine 57, 141-153, 2013 | 149 | 2013 |
Anticolon cancer activity of largazole, a marine-derived tunable histone deacetylase inhibitor Y Liu, LA Salvador, S Byeon, Y Ying, JC Kwan, BK Law, J Hong, ... Journal of pharmacology and experimental therapeutics 335 (2), 351-361, 2010 | 149 | 2010 |
Pitipeptolides A and B, New Cyclodepsipeptides from the Marine Cyanobacterium Lyngbya majuscula H Luesch, R Pangilinan, WY Yoshida, RE Moore, VJ Paul Journal of natural products 64 (3), 304-307, 2001 | 146 | 2001 |
Lyngbyastatins 5–7, Potent Elastase Inhibitors from Floridian Marine Cyanobacteria, Lyngbya spp. K Taori, S Matthew, JR Rocca, VJ Paul, H Luesch Journal of natural products 70 (10), 1593-1600, 2007 | 141 | 2007 |