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Zachary Steinhart
Zachary Steinhart
Gladstone-UCSF Institute of Genomic Immunology
Verified email at gladstone.ucsf.edu
Title
Cited by
Cited by
Year
High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities
T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, ...
Cell 163 (6), 1515-1526, 2015
16112015
Wnt signaling in development and tissue homeostasis
Z Steinhart, S Angers
Development 145 (11), dev146589, 2018
7142018
Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors
Z Steinhart, Z Pavlovic, M Chandrashekhar, T Hart, X Wang, X Zhang, ...
Nature medicine 23 (1), 60-68, 2017
3052017
Test performance evaluation of SARS-CoV-2 serological assays
JD Whitman, J Hiatt, CT Mowery, BR Shy, R Yu, TN Yamamoto, U Rathore, ...
Nature biotechnology 38 (10), 1174, 2020
2652020
Evaluation of SARS-CoV-2 serology assays reveals a range of test performance
JD Whitman, J Hiatt, CT Mowery, BR Shy, R Yu, TN Yamamoto, U Rathore, ...
Nature biotechnology 38 (10), 1174-1183, 2020
2532020
Genome-wide CRISPR-Cas9 screens expose genetic vulnerabilities and mechanisms of temozolomide sensitivity in glioblastoma stem cells
G MacLeod, DA Bozek, N Rajakulendran, V Monteiro, M Ahmadi, ...
Cell reports 27 (3), 971-986. e9, 2019
2012019
Copper bioavailability is a KRAS-specific vulnerability in colorectal cancer
L Aubert, N Nandagopal, Z Steinhart, G Lavoie, S Nourreddine, J Berman, ...
Nature communications 11 (1), 3701, 2020
1612020
CRISPR activation and interference screens decode stimulation responses in primary human T cells
R Schmidt, Z Steinhart, M Layeghi, JW Freimer, R Bueno, VQ Nguyen, ...
Science 375 (6580), eabj4008, 2022
1382022
Essential role of the Dishevelled DEP domain in a Wnt-dependent human-cell-based complementation assay
MV Gammons, TJ Rutherford, Z Steinhart, S Angers, M Bienz
Journal of cell science 129 (20), 3892-3902, 2016
832016
Tailored tetravalent antibodies potently and specifically activate Wnt/Frizzled pathways in cells, organoids and mice
Y Tao, M Mis, L Blazer, M Ustav, Z Steinhart, R Chidiac, E Kubarakos, ...
Elife 8, e46134, 2019
812019
Dishevelled is a NEK2 kinase substrate controlling dynamics of centrosomal linker proteins
I Cervenka, J Valnohova, O Bernatik, J Harnos, M Radsetoulal, K Sedova, ...
Proceedings of the National Academy of Sciences 113 (33), 9304-9309, 2016
742016
Single-molecule dynamics of Dishevelled at the plasma membrane and Wnt pathway activation
W Ma, M Chen, H Kang, Z Steinhart, S Angers, X He, MW Kirschner
Proceedings of the National Academy of Sciences 117 (28), 16690-16701, 2020
552020
A synthetic anti-Frizzled antibody engineered for broadened specificity exhibits enhanced anti-tumor properties
Z Pavlovic, JJ Adams, LL Blazer, AK Gakhal, N Jarvik, Z Steinhart, ...
MAbs 10 (8), 1157-1167, 2018
482018
IPO11 mediates βcatenin nuclear import in a subset of colorectal cancers
M Mis, S O’Brien, Z Steinhart, S Lin, T Hart, J Moffat, S Angers
Journal of Cell Biology 219 (2), e201903017, 2019
392019
An evolved AAV variant enables efficient genetic engineering of murine T cells
WA Nyberg, J Ark, A To, S Clouden, G Reeder, JJ Muldoon, JY Chung, ...
Cell 186 (2), 446-460. e19, 2023
262023
Corrigendum: Genome-wide CRISPR screens reveal a Wnt-FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors
Z Steinhart, Z Pavlovic, M Chandrashekhar, T Hart, X Wang, X Zhang, ...
Nature medicine 23 (11), 1384, 2017
102017
SCFFBXW7 regulates G2‐M progression through control of CCNL1 ubiquitination
S O'Brien, S Kelso, Z Steinhart, S Orlicky, M Mis, Y Kim, S Lin, F Sicheri, ...
EMBO reports 23 (12), e55044, 2022
82022
CRISPR activation and interference screens in primary human T cells decode cytokine regulation
R Schmidt, Z Steinhart, M Layeghi, JW Freimer, VQ Nguyen, F Blaeschke, ...
bioRxiv, 2021.05. 11.443701, 2021
72021
Systematic discovery and classification of human cell line essential genes
T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, S Angers, ...
bioRxiv, 015412, 2015
42015
The functional genomic circuitry of human glioblastoma stem cells
G MacLeod, DA Bozek, N Rajakulendran, V Monteiro, M Ahmadi, ...
BioRxiv, 358432, 2018
32018
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