Regional gene therapy with a BMP‐2‐producing murine stromal cell line induces heterotopic and orthotopic bone formation in rodents JR Lieberman, LQ Le, L Wu, GAM Finerman, A Berk, ON Witte, ... Journal of Orthopaedic Research 16 (3), 330-339, 1998 | 421 | 1998 |
Tumor microenvironment and neurofibromatosis type I: connecting the GAPs LQ Le, LF Parada Oncogene 26 (32), 4609-4616, 2007 | 245 | 2007 |
Mice lacking the orphan G protein-coupled receptor G2A develop a late-onset autoimmune syndrome LQ Le, JHS Kabarowski, Z Weng, AB Satterthwaite, ET Harvill, ER Jensen, ... Immunity 14 (5), 561-571, 2001 | 232 | 2001 |
Cell of origin and microenvironment contribution for NF1-associated dermal neurofibromas LQ Le, T Shipman, DK Burns, LF Parada Cell stem cell 4 (5), 453-463, 2009 | 194 | 2009 |
A DNA damage and stress inducible G protein-coupled receptor blocks cells in G2/M Z Weng, AC Fluckiger, S Nisitani, MI Wahl, LQ Le, CA Hunter, AA Fernal, ... Proceedings of the National Academy of Sciences 95 (21), 12334-12339, 1998 | 191 | 1998 |
Genome-wide siRNA-based functional genomics of pigmentation identifies novel genes and pathways that impact melanogenesis in human cells AK Ganesan, H Ho, B Bodemann, S Petersen, J Aruri, S Koshy, ... PLoS genetics 4 (12), e1000298, 2008 | 172 | 2008 |
CXCR4/CXCL12 mediate autocrine cell-cycle progression in NF1-associated malignant peripheral nerve sheath tumors W Mo, J Chen, A Patel, L Zhang, V Chau, Y Li, W Cho, K Lim, J Xu, ... Cell 152 (5), 1077-1090, 2013 | 168 | 2013 |
Contributions of inflammation and tumor microenvironment to neurofibroma tumorigenesis CP Liao, RC Booker, JP Brosseau, Z Chen, J Mo, E Tchegnon, Y Wang, ... The Journal of clinical investigation 128 (7), 2848-2861, 2018 | 147 | 2018 |
Cells of origin in the embryonic nerve roots for NF1-associated plexiform neurofibroma Z Chen, C Liu, AJ Patel, CP Liao, Y Wang, LQ Le Cancer cell 26 (5), 695-706, 2014 | 104 | 2014 |
Susceptible stages in Schwann cells for NF1-associated plexiform neurofibroma development LQ Le, C Liu, T Shipman, Z Chen, U Suter, LF Parada Cancer research 71 (13), 4686-4695, 2011 | 104 | 2011 |
Direct genetic demonstration of Gα13 coupling to the orphan G protein-coupled receptor G2A leading to RhoA-dependent actin rearrangement JHS Kabarowski, JD Feramisco, LQ Le, JL Gu, SW Luoh, MI Simon, ... Proceedings of the National Academy of Sciences 97 (22), 12109-12114, 2000 | 96 | 2000 |
BET bromodomain inhibition triggers apoptosis of NF1-associated malignant peripheral nerve sheath tumors through Bim induction AJ Patel, CP Liao, Z Chen, C Liu, Y Wang, LQ Le Cell reports 6 (1), 81-92, 2014 | 84 | 2014 |
Spatiotemporal loss of NF1 in Schwann cell lineage leads to different types of cutaneous neurofibroma susceptible to modification by the Hippo pathway Z Chen, J Mo, JP Brosseau, T Shipman, Y Wang, CP Liao, JM Cooper, ... Cancer Discovery 9 (1), 114-129, 2019 | 82 | 2019 |
Malignant peripheral nerve sheath tumor: models, biology, and translation BN Somatilaka, A Sadek, RM McKay, LQ Le Oncogene 41 (17), 2405-2421, 2022 | 63 | 2022 |
Positron emission tomography imaging analysis of G2A as a negative modifier of lymphoid leukemogenesis initiated by the BCR-ABL oncogene LQ Le, JHS Kabarowski, S Wong, K Nguyen, SS Gambhir, ON Witte Cancer Cell 1 (4), 381-391, 2002 | 63 | 2002 |
Humanized neurofibroma model from induced pluripotent stem cells delineates tumor pathogenesis and developmental origins J Mo, C Anastasaki, Z Chen, T Shipman, J Papke, K Yin, DH Gutmann, ... The Journal of clinical investigation 131 (1), 2021 | 61 | 2021 |
NF1 heterozygosity fosters de novo tumorigenesis but impairs malignant transformation J Brosseau, C Liao, Y Wang, V Ramani, T Vandergriff, M Lee, A Patel, ... JOURNAL OF INVESTIGATIVE DERMATOLOGY 139 (5), S63-S63, 2019 | 59 | 2019 |
NF1 heterozygosity fosters de novo tumorigenesis but impairs malignant transformation JP Brosseau, CP Liao, Y Wang, V Ramani, T Vandergriff, M Lee, A Patel, ... Nature communications 9 (1), 5014, 2018 | 59 | 2018 |
Identification of hair shaft progenitors that create a niche for hair pigmentation CP Liao, RC Booker, SJ Morrison, LQ Le Genes & development 31 (8), 744-756, 2017 | 59 | 2017 |
Cutaneous neurofibromas in the genomics era: current understanding and open questions RJ Allaway, SJC Gosline, S La Rosa, P Knight, A Bakker, J Guinney, ... British journal of cancer 118 (12), 1539-1548, 2018 | 58 | 2018 |