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Yael David
Yael David
Associate Prof., Chemical Biology Program, MSKCC
Dirección de correo verificada de mskcc.org - Página principal
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The E2 ubiquitin-conjugating enzymes direct polyubiquitination to preferred lysines
Y David, T Ziv, A Admon, A Navon
Journal of Biological Chemistry 285 (12), 8595-8604, 2010
2032010
Histone H1 loss drives lymphoma by disrupting 3D chromatin architecture
N Yusufova, A Kloetgen, M Teater, A Osunsade, JM Camarillo, CR Chin, ...
Nature 589 (7841), 299-305, 2021
1812021
Defective ubiquitinylation of EGFR mutants of lung cancer confers prolonged signaling
K Shtiegman, BS Kochupurakkal, Y Zwang, G Pines, A Starr, A Vexler, ...
Oncogene 26 (49), 6968-6978, 2007
1732007
Accelerated chromatin biochemistry using DNA-barcoded nucleosome libraries
UTT Nguyen, L Bittova, MM Müller, B Fierz, Y David, B Houck-Loomis, ...
Nature methods 11 (8), 834-840, 2014
1552014
Reversible histone glycation is associated with disease-related changes in chromatin architecture
Q Zheng, ND Omans, R Leicher, A Osunsade, AS Agustinus, ...
Nature Communications 10 (1), 1289, 2019
1442019
Chemical tagging and customizing of cellular chromatin states using ultrafast trans-splicing inteins
Y David, M Vila-Perelló, S Verma, TW Muir
Nature chemistry 7 (5), 394-402, 2015
1402015
H1 histones control the epigenetic landscape by local chromatin compaction
MA Willcockson, SE Healton, CN Weiss, BA Bartholdy, Y Botbol, ...
Nature 589 (7841), 293-298, 2021
1202021
E3 ligases determine ubiquitination site and conjugate type by enforcing specificity on E2 enzymes
Y David, N Ternette, MJ Edelmann, T Ziv, B Gayer, R Sertchook, Y Dadon, ...
Journal of Biological Chemistry 286 (51), 44104-44115, 2011
882011
Bisphosphoglycerate mutase controls serine pathway flux via 3-phosphoglycerate
RC Oslund, X Su, M Haugbro, JM Kee, M Esposito, Y David, B Wang, ...
Nature chemical biology 13 (10), 1081-1087, 2017
592017
Non-enzymatic covalent modifications: a new link between metabolism and epigenetics
Q Zheng, I Maksimovic, A Upad, Y David
Protein & cell 11 (6), 401-416, 2020
562020
Identification of a functional hotspot on ubiquitin required for stimulation of methyltransferase activity on chromatin
MT Holt, Y David, S Pollock, Z Tang, J Jeon, J Kim, RG Roeder, TW Muir
Proceedings of the National Academy of Sciences 112 (33), 10365-10370, 2015
492015
Protein arginine deiminase 4 antagonizes methylglyoxal-induced histone glycation
Q Zheng, A Osunsade, Y David
Nature Communications 11 (1), 3241, 2020
462020
Genomic targeting of epigenetic probes using a chemically tailored Cas9 system
GP Liszczak, ZZ Brown, SH Kim, RC Oslund, Y David, TW Muir
Proceedings of the National Academy of Sciences 114 (4), 681-686, 2017
462017
The human otubain2-ubiquitin structure provides insights into the cleavage specificity of poly-ubiquitin-linkages
M Altun, TS Walter, HB Kramer, P Herr, A Iphöfer, J Boström, Y David, ...
PloS one 10 (1), e0115344, 2015
412015
DOT1L complex regulates transcriptional initiation in human erythroleukemic cells
A Wu, J Zhi, T Tian, A Cihan, MA Cevher, Z Liu, Y David, TW Muir, ...
Proceedings of the National Academy of Sciences 118 (27), e2106148118, 2021
342021
Epigenetic dysregulation from chromosomal transit in micronuclei
AS Agustinus, D Al-Rawi, B Dameracharla, R Raviram, BSCL Jones, ...
Nature 619 (7968), 176-183, 2023
312023
Non-enzymatic covalent modifications as a new chapter in the histone code
I Maksimovic, Y David
Trends in biochemical sciences 46 (9), 718-730, 2021
302021
(De) Toxifying the epigenetic code
Q Zheng, NA Prescott, I Maksimovic, Y David
Chemical research in toxicology 32 (5), 796-807, 2019
302019
Single-stranded nucleic acid binding and coacervation by linker histone H1
R Leicher, A Osunsade, GNL Chua, SC Faulkner, AP Latham, JW Watters, ...
Nature structural & molecular biology 29 (5), 463-471, 2022
292022
Synthesis of an alkynyl methylglyoxal probe to investigate nonenzymatic histone glycation
Q Zheng, I Maksimovic, A Upad, D Guber, Y David
The Journal of organic chemistry 85 (3), 1691-1697, 2019
292019
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Artículos 1–20