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Kevin R Brown
Kevin R Brown
Hospital for Sick Children
Verified email at sickkids.ca
Title
Cited by
Cited by
Year
High-resolution CRISPR screens reveal fitness genes and genotype-specific cancer liabilities
T Hart, M Chandrashekhar, M Aregger, Z Steinhart, KR Brown, ...
Cell 163 (6), 1515-1526, 2015
16072015
Effectiveness of the Pfizer-BioNTech and Oxford-AstraZeneca vaccines on covid-19 related symptoms, hospital admissions, and mortality in older adults in England: test negative …
JL Bernal, N Andrews, C Gower, C Robertson, J Stowe, E Tessier, ...
bmj 373, 2021
12432021
High-throughput mapping of a dynamic signaling network in mammalian cells
M Barrios-Rodiles, KR Brown, B Ozdamar, R Bose, Z Liu, RS Donovan, ...
Science 307 (5715), 1621-1625, 2005
8802005
Idiopathic pulmonary fibrosis: relationship between histopathologic features and mortality
TE KING JR, MI Schwarz, K Brown, JA Tooze, TV Colby, JA Waldron Jr, ...
American journal of respiratory and critical care medicine 164 (6), 1025-1032, 2001
8212001
Online predicted human interaction database
KR Brown, I Jurisica
Bioinformatics 21 (9), 2076-2082, 2005
7512005
Evaluation and design of genome-wide CRISPR/SpCas9 knockout screens
T Hart, AHY Tong, K Chan, J Van Leeuwen, A Seetharaman, M Aregger, ...
G3: Genes, Genomes, Genetics 7 (8), 2719-2727, 2017
4812017
Functional genomic landscape of human breast cancer drivers, vulnerabilities, and resistance
R Marcotte, A Sayad, KR Brown, F Sanchez-Garcia, J Reimand, M Haider, ...
Cell 164 (1), 293-309, 2016
4542016
Unequal evolutionary conservation of human protein interactions in interologous networks
KR Brown, I Jurisica
Genome biology 8, 1-11, 2007
3762007
Essential gene profiles in breast, pancreatic, and ovarian cancer cells
R Marcotte, KR Brown, F Suarez, A Sayad, K Karamboulas, ...
Cancer discovery 2 (2), 172-189, 2012
3752012
Measuring error rates in genomic perturbation screens: gold standards for human functional genomics
T Hart, KR Brown, F Sircoulomb, R Rottapel, J Moffat
Molecular systems biology 10 (7), 733, 2014
3692014
Colorectal cancer cells enter a diapause-like DTP state to survive chemotherapy
SK Rehman, J Haynes, E Collignon, KR Brown, Y Wang, AML Nixon, ...
Cell 184 (1), 226-242. e21, 2021
3142021
Genome-wide CRISPR screens reveal a Wnt–FZD5 signaling circuit as a druggable vulnerability of RNF43-mutant pancreatic tumors
Z Steinhart, Z Pavlovic, M Chandrashekhar, T Hart, X Wang, X Zhang, ...
Nature medicine 23 (1), 60-68, 2017
3132017
Functional genomic landscape of cancer-intrinsic evasion of killing by T cells
KA Lawson, CM Sousa, X Zhang, E Kim, R Akthar, JJ Caumanns, Y Yao, ...
Nature 586 (7827), 120-126, 2020
2892020
Idiopathic interstitial pneumonia: do community and academic physicians agree on diagnosis?
KR Flaherty, AC Andrei, TE King Jr, G Raghu, TV Colby, A Wells, ...
American journal of respiratory and critical care medicine 175 (10), 1054-1060, 2007
2882007
NAViGaTOR: network analysis, visualization and graphing Toronto
KR Brown, D Otasek, M Ali, MJ McGuffin, W Xie, B Devani, IL Toch, ...
Bioinformatics 25 (24), 3327-3329, 2009
2872009
Regulation of epidermal growth factor receptor trafficking by lysine deacetylase HDAC6
Y Lissanu Deribe, P Wild, A Chandrashaker, J Curak, MHH Schmidt, ...
Science signaling 2 (102), ra84-ra84, 2009
2282009
A proteome resource of ovarian cancer ascites: integrated proteomic and bioinformatic analyses to identify putative biomarkers
L Gortzak-Uzan, A Ignatchenko, AI Evangelou, M Agochiya, KA Brown, ...
Journal of proteome research 7 (01), 339-351, 2008
1912008
System-wide modulation of HECT E3 ligases with selective ubiquitin variant probes
W Zhang, KP Wu, MA Sartori, HB Kamadurai, A Ordureau, C Jiang, ...
Molecular cell 62 (1), 121-136, 2016
1762016
Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9–Cas12a platform
T Gonatopoulos-Pournatzis, M Aregger, KR Brown, S Farhangmehr, ...
Nature biotechnology 38 (5), 638-648, 2020
1142020
Reasoning without logic
PN Johnson-Laird, T Myers, K Brown, B McGonigle
Reasoning and discourse processes, 13-49, 1986
1131986
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Articles 1–20