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Niek van Wietmarschen
Niek van Wietmarschen
National Cancer Institute, National Institutes of Health (NIH)
Dirección de correo verificada de nih.gov
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Dual roles of poly (dA: dT) tracts in replication initiation and fork collapse
A Tubbs, S Sridharan, N van Wietmarschen, Y Maman, E Callen, ...
Cell 174 (5), 1127-1142. e19, 2018
1832018
The developmental potential of iPSCs is greatly influenced by reprogramming factor selection
Y Buganim, S Markoulaki, N Van Wietmarschen, H Hoke, T Wu, K Ganz, ...
Cell stem cell 15 (3), 295-309, 2014
1802014
Neuronal enhancers are hotspots for DNA single-strand break repair
W Wu, SE Hill, WJ Nathan, J Paiano, E Callen, D Wang, K Shinoda, ...
Nature 593 (7859), 440-444, 2021
1432021
Repeat expansions confer WRN dependence in microsatellite-unstable cancers
N van Wietmarschen, S Sridharan, WJ Nathan, A Tubbs, EM Chan, ...
Nature 586 (7828), 292-298, 2020
1172020
BLM helicase suppresses recombination at G-quadruplex motifs in transcribed genes
N van Wietmarschen, S Merzouk, N Halsema, DCJ Spierings, V Guryev, ...
Nature communications 9 (1), 271, 2018
1032018
Extensive nuclear reprogramming underlies lineage conversion into functional trophoblast stem-like cells
H Benchetrit, S Herman, N van Wietmarschen, T Wu, K Makedonski, ...
Cell stem cell 17 (5), 543-556, 2015
802015
Direct chromosome-length haplotyping by single-cell sequencing
D Porubský, AD Sanders, N Van Wietmarschen, E Falconer, M Hills, ...
Genome research 26 (11), 1565-1574, 2016
622016
The mammalian proteins MMS19, MIP18, and ANT2 are involved in cytoplasmic iron-sulfur cluster protein assembly
N van Wietmarschen, A Moradian, GB Morin, PM Lansdorp, EJ Uringa
Journal of Biological Chemistry 287 (52), 43351-43358, 2012
602012
Helicases FANCJ, RTEL1 and BLM Act on Guanine Quadruplex DNA in Vivo
P Lansdorp, N van Wietmarschen
Genes 10 (11), 870, 2019
352019
Bromodeoxyuridine does not contribute to sister chromatid exchange events in normal or Bloom syndrome cells
N van Wietmarschen, PM Lansdorp
Nucleic acids research 44 (14), 6787-6793, 2016
332016
The WRN helicase: resolving a new target in microsatellite unstable cancers
N van Wietmarschen, WJ Nathan, A Nussenzweig
Current opinion in genetics & development 71, 34-38, 2021
182021
Mechanism for synthetic lethality in BRCA-deficient cancers: no longer lagging behind
N van Wietmarschen, A Nussenzweig
Molecular cell 71 (6), 877-878, 2018
172018
S1-END-seq reveals DNA secondary structures in human cells
G Matos-Rodrigues, N van Wietmarschen, W Wu, V Tripathi, NC Koussa, ...
Molecular cell 82 (19), 3538-3552. e5, 2022
162022
Disrupted control of origin activation compromises genome integrity upon destabilization of Polε and dysfunction of the TRP53-CDKN1A/P21 axis
V Borel, S Boeing, N Van Wietmarschen, S Sridharan, BR Hill, L Ombrato, ...
Cell Reports 39 (9), 2022
32022
High density sequencing and multiplexed priming
EN Glezer, D Witters, N Van Wietmarschen
US Patent 11,649,452, 2023
12023
High density sequencing and multiplexed priming
EN Glezer, D Witters, N Van Wietmarschen
US Patent 11,578,320, 2023
12023
High density sequencing and multiplexed priming
EN Glezer, D Witters, N Van Wietmarschen
US Patent App. 18/154,639, 2023
2023
Performance Assessment of the G4 Sequencer: A Novel Platform for Rapid and Flexible Next-Generation Sequencing
T Looney, N Van Wietmarschen, L LaMarca, K Gouin, A Decker, S Shore, ...
JOURNAL OF MOLECULAR DIAGNOSTICS 24 (10), S138-S138, 2022
2022
Genome instability: Lessons from single-cell sequencing studies
N van Wietmarschen
2016
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Artículos 1–19