| Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia AC Schinzel, O Takeuchi, Z Huang, JK Fisher, Z Zhou, J Rubens, C Hetz, ... Proceedings of the National Academy of Sciences 102 (34), 12005-12010, 2005 | 942 | 2005 |
| Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression S Takeda, DY Chen, TD Westergard, JK Fisher, JA Rubens, S Sasagawa, ... Genes & development 20 (17), 2397-2409, 2006 | 196 | 2006 |
| Arginine methylation of yeast mRNA-binding protein Npl3 directly affects its function, nuclear export, and intranuclear protein interactions AE McBride, JT Cook, EA Stemmler, KL Rutledge, KA McGrath, ... Journal of Biological Chemistry 280 (35), 30888-30898, 2005 | 134 | 2005 |
| Disrupting LIN28 in atypical teratoid rhabdoid tumors reveals the importance of the mitogen activated protein kinase pathway as a therapeutic target MF Weingart, JJ Roth, M Hutt-Cabezas, TM Busse, H Kaur, A Price, ... Oncotarget 6 (5), 3165, 2015 | 85 | 2015 |
| Identifying potential regulators of infantile hemangioma progression through large-scale expression analysis: a possible role for the immune system and indoleamine 2, 3 … MR Ritter, SK Moreno, MI Dorrell, J Rubens, J Ney, D Fallon Friedlander, ... Lymphatic research and biology 1 (4), 291-299, 2003 | 77 | 2003 |
| The dual mTOR kinase inhibitor TAK228 inhibits tumorigenicity and enhances radiosensitization in diffuse intrinsic pontine glioma H Miyahara, S Yadavilli, M Natsumeda, JA Rubens, L Rodgers, ... Cancer letters 400, 110-116, 2017 | 61 | 2017 |
| The VDAC2-BAK rheostat controls thymocyte survival D Ren, H Kim, HC Tu, TD Westergard, JK Fisher, JA Rubens, ... Science signaling 2 (85), ra48-ra48, 2009 | 56 | 2009 |
| Unbiased metabolic profiling predicts sensitivity of high MYC-expressing atypical teratoid/rhabdoid tumors to glutamine inhibition with 6-diazo-5-oxo-L-norleucine SZ Wang, B Poore, J Alt, A Price, SJ Allen, AR Hanaford, H Kaur, BA Orr, ... Clinical Cancer Research 25 (19), 5925-5936, 2019 | 24 | 2019 |
| Inhibition of mTORC1 in pediatric low-grade glioma depletes glutathione and therapeutically synergizes with carboplatin B Poore, M Yuan, A Arnold, A Price, J Alt, JA Rubens, BS Slusher, ... Neuro-oncology 21 (2), 252-263, 2019 | 24 | 2019 |
| The TORC1/2 inhibitor TAK228 sensitizes atypical teratoid rhabdoid tumors to cisplatin-induced cytotoxicity JA Rubens, SZ Wang, A Price, MF Weingart, SJ Allen, BA Orr, ... Neuro-oncology 19 (10), 1361-1371, 2017 | 22 | 2017 |
| Conditional reprogramming culture conditions facilitate growth of lower-grade glioma models M Yuan, D White, L Resar, E Bar, M Groves, A Cohen, E Jackson, ... Neuro-oncology 23 (5), 770-782, 2021 | 21 | 2021 |
| Ribavirin as a potential therapeutic for atypical teratoid/rhabdoid tumors J Casaos, S Huq, T Lott, R Felder, J Choi, N Gorelick, M Peters, Y Xia, ... Oncotarget 9 (8), 8054, 2018 | 18 | 2018 |
| Generation and multi-dimensional profiling of a childhood cancer cell line atlas defines new therapeutic opportunities CX Sun, P Daniel, G Bradshaw, H Shi, M Loi, N Chew, S Parackal, V Tsui, ... Cancer cell 41 (4), 660-677. e7, 2023 | 11 | 2023 |
| Recent progress and novel approaches to treating atypical teratoid rhabdoid tumor E Alva, J Rubens, S Chi, T Rosenberg, A Reddy, EH Raabe, A Margol Neoplasia 37, 100880, 2023 | 7 | 2023 |
| Unbiased proteomic and phosphoproteomic analysis identifies response signatures and novel susceptibilities after combined MEK and mTOR inhibition in BRAFV600E mutant glioma MJ Maxwell, A Arnold, H Sweeney, L Chen, TSM Lih, M Schnaubelt, ... Molecular & Cellular Proteomics 20, 2021 | 6 | 2021 |
| Dual mTORC1/2 inhibition compromises cell defenses against exogenous stress potentiating Obatoclax-induced cytotoxicity in atypical teratoid/rhabdoid tumors A Parkhurst, SZ Wang, TR Findlay, KJ Malebranche, A Odabas, J Alt, ... Cell Death & Disease 13 (4), 410, 2022 | 5 | 2022 |
| MEK inhibition suppresses growth of atypical teratoid/rhabdoid tumors S Shahab, J Rubens, H Kaur, H Sweeney, CG Eberhart, EH Raabe Journal of Neuropathology & Experimental Neurology 79 (7), 746-753, 2020 | 4 | 2020 |
| Long‐term survival in a pediatric patient with supratentorial primitive neuro‐ectodermal tumor and extraneural metastasis at diagnosis J Rubens, Y Gosiengfiao, T Tomita, DA Jacobsohn, J Fangusaro Pediatric Blood & Cancer 57 (2), 341-344, 2011 | 4 | 2011 |
| Five pediatric cancers–update on genetic implications S Cooper, J Rubens, J Bodurtha Current Pediatric Reviews 13 (1), 42-48, 2017 | 3 | 2017 |
| The PI3K inhibitor Paxalisib combines synergistically with the pan-Raf inhibitor TAK580 (DAY 101) to extend survival in orthotopic xenograft models of atypical teratoid … K Malebranche, T Findlay, C Eberhart, E Raabe, J Rubens Cancer Research 82 (12_Supplement), 5226-5226, 2022 | 2 | 2022 |
