| The Collaborative Cross, a community resource for the genetic analysis of complex traits Nature genetics 36 (11), 1133-1137, 2004 | 1129 | 2004 |
| Consensus guidelines for the detection of immunogenic cell death O Kepp, L Senovilla, I Vitale, E Vacchelli, S Adjemian, P Agostinis, ... Oncoimmunology 3 (9), e955691, 2014 | 799 | 2014 |
| Nicotinic acetylcholine binding sites in Alzheimer's disease PJ Whitehouse, AM Martino, PG Antuono, PR Lowenstein, JT Coyle, ... Brain research 371 (1), 146-151, 1986 | 576 | 1986 |
| Platelets mediate cytotoxic T lymphocyte–induced liver damage M Iannacone, G Sitia, M Isogawa, P Marchese, MG Castro, ... Nature medicine 11 (11), 1167-1169, 2005 | 421 | 2005 |
| Intracranial glioblastoma models in preclinical neuro-oncology: neuropathological characterization and tumor progression M Candolfi, JF Curtin, WS Nichols, AKMG Muhammad, GD King, ... Journal of neuro-oncology 85, 133-148, 2007 | 410 | 2007 |
| HMGB1 mediates endogenous TLR2 activation and brain tumor regression JF Curtin, N Liu, M Candolfi, W Xiong, H Assi, K Yagiz, MR Edwards, ... PLoS medicine 6 (1), e1000010, 2009 | 388 | 2009 |
| Chronic brain inflammation and persistent herpes simplex virus 1 thymidine kinase expression in survivors of syngeneic glioma treated by adenovirus-mediated gene therapy … RA Dewey, G Morrissey, CM Cowsill, D Stone, F Bolognani, NJF Dodd, ... Nature medicine 5 (11), 1256-1263, 1999 | 374 | 1999 |
| Regulatable gene expression systems for gene therapy applications: progress and future challenges S Goverdhana, M Puntel, W Xiong, JM Zirger, C Barcia, JF Curtin, ... Molecular Therapy 12 (2), 189-211, 2005 | 348 | 2005 |
| Peripheral infection with adenovirus causes unexpected long-term brain inflammation in animals injected intracranially with first-generation, but not with high-capacity … CE Thomas, G Schiedner, S Kochanek, MG Castro, PR Löwenstein Proceedings of the National Academy of Sciences 97 (13), 7482-7487, 2000 | 288 | 2000 |
| Response of foot-and-mouth disease virus to increased mutagenesis: influence of viral load and fitness in loss of infectivity S Sierra, M Dávila, PR Lowenstein, E Domingo Journal of virology 74 (18), 8316-8323, 2000 | 284 | 2000 |
| Current and future strategies for the treatment of malignant brain tumors MG Castro, R Cowen, IK Williamson, A David, MJ Jimenez-Dalmaroni, ... Pharmacology & therapeutics 98 (1), 71-108, 2003 | 255 | 2003 |
| ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma C Koschmann, AA Calinescu, FJ Nunez, A Mackay, J Fazal-Salom, ... Science translational medicine 8 (328), 328ra28-328ra28, 2016 | 249 | 2016 |
| Progress in gene therapy for neurological disorders M Simonato, J Bennett, NM Boulis, MG Castro, DJ Fink, WF Goins, ... Nature Reviews Neurology 9 (5), 277-291, 2013 | 245 | 2013 |
| Acute direct adenoviral vector cytotoxicity and chronic, but not acute, inflammatory responses correlate with decreased vector-mediated transgene expression in the brain CE Thomas, D Birkett, I Anozie, MG Castro, PR Lowenstein Molecular Therapy 3 (1), 36-46, 2001 | 201 | 2001 |
| Suppression of viral infectivity through lethal defection A Grande-Pérez, E Lázaro, P Lowenstein, E Domingo, SC Manrubia Proceedings of the National Academy of Sciences 102 (12), 4448-4452, 2005 | 200 | 2005 |
| IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response FJ Núñez, FM Mendez, P Kadiyala, MS Alghamri, MG Savelieff, ... Science translational medicine 11 (479), eaaq1427, 2019 | 199 | 2019 |
| Immune responses to adenovirus and adeno-associated vectors used for gene therapy of brain diseases: the role of immunological synapses in understanding the cell biology of … PR Lowenstein, RJ Mandel, W Xiong, K Kroeger, MG Castro Current gene therapy 7 (5), 347-360, 2007 | 186 | 2007 |
| Stability of lentiviral vector-mediated transgene expression in the brain in the presence of systemic antivector immune responses E Abordo-Adesida, A Follenzi, C Barcia, S Sciascia, MG Castro, L Naldini, ... Human gene therapy 16 (6), 741-751, 2005 | 186 | 2005 |
| Efficient FLPe recombinase enables scalable production of helper-dependent adenoviral vectors with negligible helper-virus contamination P Umana, CA Gerdes, D Stone, JRE Davis, D Ward, MG Castro, ... Nature biotechnology 19 (6), 582-585, 2001 | 183 | 2001 |
| Efficient virus extinction by combinations of a mutagen and antiviral inhibitors N Pariente, S Sierra, PR Lowenstein, E Domingo Journal of Virology 75 (20), 9723-9730, 2001 | 178 | 2001 |
Maria G CastroUniversity of Michigan Medical School, Ann Arbor, MIVerified email at umich.edu
