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Gewirtz AT
Gewirtz AT
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Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5
M Vijay-Kumar, JD Aitken, FA Carvalho, TC Cullender, S Mwangi, ...
Science 328 (5975), 228-231, 2010
23992010
Dietary emulsifiers impact the mouse gut microbiota promoting colitis and metabolic syndrome
B Chassaing, O Koren, JK Goodrich, AC Poole, S Srinivasan, RE Ley, ...
Nature 519 (7541), 92-96, 2015
19512015
Cutting edge: bacterial flagellin activates basolaterally expressed TLR5 to induce epithelial proinflammatory gene expression
AT Gewirtz, TA Navas, S Lyons, PJ Godowski, JL Madara
The Journal of Immunology 167 (4), 1882-1885, 2001
17502001
Prokaryotic regulation of epithelial responses by inhibition of IκB-α ubiquitination
AS Neish, AT Gewirtz, H Zeng, AN Young, ME Hobert, V Karmali, AS Rao, ...
Science 289 (5484), 1560-1563, 2000
11802000
Bacteria penetrate the normally impenetrable inner colon mucus layer in both murine colitis models and patients with ulcerative colitis
MEV Johansson, JK Gustafsson, J Holmén-Larsson, KS Jabbar, L Xia, ...
Gut 63 (2), 281-291, 2014
9252014
Cutting edge: impaired Toll-like receptor expression and function in aging
M Renshaw, J Rockwell, C Engleman, A Gewirtz, J Katz, S Sambhara
The Journal of Immunology 169 (9), 4697-4701, 2002
7302002
Dysregulation of inflammatory responses by chronic circadian disruption
O Castanon-Cervantes, M Wu, JC Ehlen, K Paul, KL Gamble, RL Johnson, ...
The Journal of Immunology 185 (10), 5796-5805, 2010
5852010
Regulation of Legionella phagosome maturation and infection through flagellin and host Ipaf
A Amer, L Franchi, TD Kanneganti, M Body-Malapel, N Ozoren, G Brady, ...
Journal of Biological Chemistry 281 (46), 35217-35223, 2006
5692006
Salmonella typhimurium translocates flagellin across intestinal epithelia, inducing a proinflammatory response
AT Gewirtz, PO Simon, CK Schmitt, LJ Taylor, CH Hagedorn, AD O’Brien, ...
The Journal of clinical investigation 107 (1), 99-109, 2001
5192001
Sex steroid deficiency–associated bone loss is microbiota dependent and prevented by probiotics
JY Li, B Chassaing, AM Tyagi, C Vaccaro, T Luo, J Adams, TM Darby, ...
The Journal of clinical investigation 126 (6), 2049-2063, 2016
5182016
Transient inability to manage proteobacteria promotes chronic gut inflammation in TLR5-deficient mice
FA Carvalho, O Koren, JK Goodrich, MEV Johansson, I Nalbantoglu, ...
Cell host & microbe 12 (2), 139-152, 2012
5112012
Deletion of TLR5 results in spontaneous colitis in mice
M Vijay-Kumar, CJ Sanders, RT Taylor, A Kumar, JD Aitken, ...
The Journal of clinical investigation 117 (12), 3909-3921, 2007
5032007
TLR5-mediated sensing of gut microbiota is necessary for antibody responses to seasonal influenza vaccination
JZ Oh, R Ravindran, B Chassaing, FA Carvalho, MS Maddur, M Bower, ...
Immunity 41 (3), 478-492, 2014
5012014
Fecal lipocalin 2, a sensitive and broadly dynamic non-invasive biomarker for intestinal inflammation
B Chassaing, G Srinivasan, MA Delgado, AN Young, AT Gewirtz, ...
Public Library of Science 7 (9), e44328, 2012
4962012
Fiber-mediated nourishment of gut microbiota protects against diet-induced obesity by restoring IL-22-mediated colonic health
J Zou, B Chassaing, V Singh, M Pellizzon, M Ricci, MD Fythe, MV Kumar, ...
Cell host & microbe 23 (1), 41-53. e4, 2018
4792018
Dietary emulsifiers directly alter human microbiota composition and gene expression ex vivo potentiating intestinal inflammation
B Chassaing, T Van de Wiele, J De Bodt, M Marzorati, AT Gewirtz
Gut 66 (8), 1414-1427, 2017
4752017
Antibiotics-driven gut microbiome perturbation alters immunity to vaccines in humans
T Hagan, M Cortese, N Rouphael, C Boudreau, C Linde, MS Maddur, ...
Cell 178 (6), 1313-1328. e13, 2019
4542019
Dysregulated microbial fermentation of soluble fiber induces cholestatic liver cancer
V Singh, B San Yeoh, B Chassaing, X Xiao, P Saha, RA Olvera, JD Lapek, ...
Cell 175 (3), 679-694. e22, 2018
4042018
Gut microbial products regulate murine gastrointestinal motility via Toll-like receptor 4 signaling
M Anitha, M Vijay–Kumar, SV Sitaraman, AT Gewirtz, S Srinivasan
Gastroenterology 143 (4), 1006-1016. e4, 2012
3862012
Microbiota‐liver axis in hepatic disease
B Chassaing, L Etienne‐Mesmin, AT Gewirtz
Hepatology 59 (1), 328-339, 2014
3732014
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