| Synonymous mutations frequently act as driver mutations in human cancers F Supek, B Miñana, J Valcárcel, T Gabaldón, B Lehner Cell 156 (6), 1324-1335, 2014 | 627 | 2014 |
| Regulatory defects in liver and intestine implicate abnormal hepcidin and Cybrd1 expression in mouse hemochromatosis M Muckenthaler, CN Roy, ÁO Custodio, B Miñana, J DeGraaf, ... Nature genetics 34 (1), 102-107, 2003 | 371 | 2003 |
| Reduced fidelity of branch point recognition and alternative splicing induced by the anti-tumor drug spliceostatin A A Corrionero, B Miñana, J Valcárcel Genes & development 25 (5), 445-459, 2011 | 285 | 2011 |
| Large-scale analysis of genome and transcriptome alterations in multiple tumors unveils novel cancer-relevant splicing networks E Sebestyén, B Singh, B Miñana, A Pagès, F Mateo, MA Pujana, ... Genome research 26 (6), 732-744, 2016 | 284 | 2016 |
| Altered body iron distribution and microcytosis in mice deficient in iron regulatory protein 2 (IRP2) B Galy, D Ferring, B Minana, O Bell, HG Janser, M Muckenthaler, ... Blood 106 (7), 2580-2589, 2005 | 260 | 2005 |
| The Ewing sarcoma protein regulates DNA damage-induced alternative splicing MP Paronetto, B Miñana, J Valcárcel Molecular cell 43 (3), 353-368, 2011 | 197 | 2011 |
| CPEB1 coordinates alternative 3′-UTR formation with translational regulation FA Bava, C Eliscovich, PG Ferreira, B Minana, C Ben-Dov, R Guigo, ... Nature 495 (7439), 121-125, 2013 | 194 | 2013 |
| Mapping and identification of essential gene functions on the X chromosome of Drosophila A Peter, P Schöttler, M Werner, N Beinert, G Dowe, P Burkert, F Mourkioti, ... EMBO reports 3 (1), 34-38, 2002 | 128 | 2002 |
| The complete local genotype–phenotype landscape for the alternative splicing of a human exon P Julien, B Miñana, P Baeza-Centurion, J Valcárcel, B Lehner Nature communications 7 (1), 11558, 2016 | 120 | 2016 |
| Argonaute-1 binds transcriptional enhancers and controls constitutive and alternative splicing in human cells M Alló, E Agirre, S Bessonov, P Bertucci, L Gómez Acuña, V Buggiano, ... Proceedings of the National Academy of Sciences 111 (44), 15622-15629, 2014 | 114 | 2014 |
| Combinatorial genetics reveals a scaling law for the effects of mutations on splicing P Baeza-Centurion, B Miñana, JM Schmiedel, J Valcárcel, B Lehner Cell 176 (3), 549-563. e23, 2019 | 105 | 2019 |
| Distinction between asymptomatic monoclonal B-cell lymphocytosis with cyclin D1 overexpression and mantle cell lymphoma: from molecular profiling to flow cytometry B Espinet, A Ferrer, B Bellosillo, L Nonell, A Salar, ... Clinical Cancer Research 20 (4), 1007-1019, 2014 | 52 | 2014 |
| Molecular analysis of iron overload in β2-microglobulin-deficient mice MU Muckenthaler, P Rodrigues, MG Macedo, B Minana, K Brennan, ... Blood Cells, Molecules, and Diseases 33 (2), 125-131, 2004 | 49 | 2004 |
| Distinct regulatory programs establish widespread sex-specific alternative splicing in Drosophila melanogaster B Hartmann, R Castelo, B Miñana, E Peden, M Blanchette, DC Rio, ... Rna 17 (3), 453-468, 2011 | 46 | 2011 |
| Genotoxic stress inhibits Ewing sarcoma cell growth by modulating alternative pre-mRNA processing of the RNA helicase DHX9 M Fidaleo, F Svetoni, E Volpe, B Miñana, D Caporossi, MP Paronetto Oncotarget 6 (31), 31740, 2015 | 44 | 2015 |
| Mutational analysis of progesterone receptor functional domains in stable cell lines delineates sets of genes regulated by different mechanisms I Quiles, L Millan-Arino, A Subtil-Rodríguez, B Minana, N Spinedi, ... Molecular Endocrinology 23 (6), 809-826, 2009 | 40 | 2009 |
| From Sequence to Chromosome: The Tip of the X Chromosome of D. melanogaster PV Benos, MK Gatt, M Ashburner, L Murphy, D Harris, B Barrell, C Ferraz, ... Science 287 (5461), 2220-2222, 2000 | 40 | 2000 |
| Cloning and molecular characterization of two mosquito iron regulatory proteins D Zhang, G Dimopoulos, A Wolf, B Minana, FC Kafatos, JJ Winzerling Insect biochemistry and molecular biology 32 (5), 579-589, 2002 | 39 | 2002 |
| Mutations primarily alter the inclusion of alternatively spliced exons P Baeza-Centurion, B Miñana, J Valcárcel, B Lehner Elife 9, e59959, 2020 | 35 | 2020 |
| From first base: the sequence of the tip of the X chromosome of Drosophila melanogaster, a comparison of two sequencing strategies PV Benos, MK Gatt, L Murphy, D Harris, B Barrell, C Ferraz, S Vidal, ... Genome Research 11 (5), 710-730, 2001 | 33 | 2001 |
Juan ValcarcelICREA Research Professor, Center for Genomic RegulationVerified email at crg.eu
