Cannabinergic ligands SL Palmer, GA Thakur, A Makriyannis Chemistry and Physics of Lipids 121 (1-2), 3-19, 2002 | 198 | 2002 |
The novel cannabinoid CB1 receptor neutral antagonist AM4113 suppresses food intake and food-reinforced behavior but does not induce signs of nausea in rats KS Sink, PJ McLaughlin, JAT Wood, C Brown, P Fan, VK Vemuri, Y Pang, ... Neuropsychopharmacology 33 (4), 946-955, 2008 | 185 | 2008 |
Selective activation of cannabinoid CB2 receptors suppresses neuropathic nociception induced by treatment with the chemotherapeutic agent paclitaxel in rats EJ Rahn, AM Zvonok, GA Thakur, AD Khanolkar, A Makriyannis, ... Journal of Pharmacology and Experimental Therapeutics 327 (2), 584-591, 2008 | 138 | 2008 |
CB1 cannabinoid receptor ligands GA Thakur, SP Nikas, A Makriyannis Mini reviews in medicinal chemistry 5 (7), 631-640, 2005 | 133 | 2005 |
Positive allosteric modulation of cannabinoid receptor type 1 suppresses pathological pain without producing tolerance or dependence RA Slivicki, Z Xu, PM Kulkarni, RG Pertwee, K Mackie, GA Thakur, ... Biological psychiatry 84 (10), 722-733, 2018 | 128 | 2018 |
Ligand-binding architecture of human CB2 cannabinoid receptor: evidence for receptor subtype-specific binding motif and modeling GPCR activation Y Pei, RW Mercier, JK Anday, GA Thakur, AM Zvonok, D Hurst, ... Chemistry & biology 15 (11), 1207-1219, 2008 | 118 | 2008 |
Latest advances in cannabinoid receptor agonists GA Thakur, R Tichkule, S Bajaj, A Makriyannis Expert opinion on therapeutic patents 19 (12), 1647-1673, 2009 | 116 | 2009 |
(-)-7′-Isothiocyanato-11-hydroxy-1′, 1′-dimethylheptylhexahydrocannabinol (AM841), a high-affinity electrophilic ligand, interacts covalently with a cysteine in helix six … RP Picone, AD Khanolkar, W Xu, LA Ayotte, GA Thakur, DP Hurst, ... Molecular pharmacology 68 (6), 1623-1635, 2005 | 115 | 2005 |
Cannabilactones: a novel class of CB2 selective agonists with peripheral analgesic activity AD Khanolkar, D Lu, M Ibrahim, RI Duclos, Jr, GA Thakur, TP Malan, Jr, ... Journal of medicinal chemistry 50 (26), 6493-6500, 2007 | 111 | 2007 |
Natural cannabinoids: templates for drug discovery GA Thakur, RI Duclos Jr, A Makriyannis Life sciences 78 (5), 454-466, 2005 | 107 | 2005 |
Intrathecal cannabilactone CB2R agonist, AM1710, controls pathological pain and restores basal cytokine levels JL Wilkerson, KR Gentry, EC Dengler, JA Wallace, AA Kerwin, LM Armijo, ... PAIN® 153 (5), 1091-1106, 2012 | 104 | 2012 |
A Novel Example of Metal-Mediated Aromatic Thiolation in a Ruthenium Complex. Crystal Structure of RuII (SC6H4N NC6H4N) 2 BK Santra, GA Thakur, P Ghosh, A Pramanik, GK Lahiri Inorganic Chemistry 35 (10), 3050-3052, 1996 | 104 | 1996 |
Mutation studies of Ser7. 39 and Ser2. 60 in the human CB1 cannabinoid receptor: evidence for a serine-induced bend in CB1 transmembrane helix 7 A Kapur, DP Hurst, D Fleischer, R Whitnell, GA Thakur, A Makriyannis, ... Molecular pharmacology 71 (6), 1512-1524, 2007 | 101 | 2007 |
Enantiospecific allosteric modulation of cannabinoid 1 receptor RB Laprairie, PM Kulkarni, JR Deschamps, MEM Kelly, DR Janero, ... ACS chemical neuroscience 8 (6), 1188-1203, 2017 | 99 | 2017 |
The analgesic-like properties of the alpha7 nAChR silent agonist NS6740 is associated with non-conducting conformations of the receptor RL Papke, D Bagdas, AR Kulkarni, T Gould, SD AlSharari, GA Thakur, ... Neuropharmacology 91, 34-42, 2015 | 97 | 2015 |
The Maintenance of Cisplatin- and Paclitaxel-Induced Mechanical and Cold Allodynia is Suppressed by Cannabinoid CB2 Receptor Activation and Independent of … L Deng, J Guindon, VK Vemuri, GA Thakur, FA White, A Makriyannis, ... Molecular pain 8, 1744-8069-8-71, 2012 | 97 | 2012 |
Polyamidoamine dendrimers-based nanomedicine for combination therapy with siRNA and chemotherapeutics to overcome multidrug resistance J Pan, LP Mendes, M Yao, N Filipczak, S Garai, GA Thakur, C Sarisozen, ... European Journal of Pharmaceutics and Biopharmaceutics 136, 18-28, 2019 | 95 | 2019 |
Adamantyl cannabinoids: a novel class of cannabinergic ligands D Lu, Z Meng, GA Thakur, P Fan, J Steed, CL Tartal, DP Hurst, PH Reggio, ... Journal of medicinal chemistry 48 (14), 4576-4585, 2005 | 91 | 2005 |
The α7 nicotinic receptor dual allosteric agonist and positive allosteric modulator GAT107 reverses nociception in mouse models of inflammatory and neuropathic pain D Bagdas, JL Wilkerson, A Kulkarni, W Toma, S AlSharari, Z Gul, ... British Journal of Pharmacology 173 (16), 2506-2520, 2016 | 78 | 2016 |
Cannabinoid receptors as therapeutic targets S Pavlopoulos, GA Thakur, SP Nikas, A Makriyannis Current pharmaceutical design 12 (14), 1751-1769, 2006 | 77 | 2006 |