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Christopher D. Dupont
Christopher D. Dupont
Dirección de correo verificada de mit.edu
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Immune response and immunopathology during toxoplasmosis
CD Dupont, DA Christian, CA Hunter
Seminars in immunopathology 34, 793-813, 2012
4222012
Interleukin-27 priming of T cells controls IL-17 production in trans via induction of the ligand PD-L1
K Hirahara, K Ghoreschi, XP Yang, H Takahashi, A Laurence, G Vahedi, ...
Immunity 36 (6), 1017-1030, 2012
2982012
Parasite Fate and Involvement of Infected Cells in the Induction of CD4+ and CD8+ T Cell Responses to Toxoplasma gondii
CD Dupont, DA Christian, EM Selleck, M Pepper, M Leney-Greene, ...
PLoS pathogens 10 (4), e1004047, 2014
1012014
Virulence of Toxoplasma gondii is associated with distinct dendritic cell responses and reduced numbers of activated CD8+ T cells
ED Tait, KA Jordan, CD Dupont, TH Harris, B Gregg, EH Wilson, ...
The Journal of Immunology 185 (3), 1502-1512, 2010
742010
A host GPCR signaling network required for the cytolysis of infected cells facilitates release of apicomplexan parasites
MG Millholland, S Mishra, CD Dupont, MS Love, B Patel, D Shilling, ...
Cell host & microbe 13 (1), 15-28, 2013
502013
African trypanosomes contain 5-methylcytosine in nuclear DNA
KT Militello, P Wang, SK Jayakar, RL Pietrasik, CD Dupont, K Dodd, ...
Eukaryotic cell 7 (11), 2012-2016, 2008
412008
Toxicological and pharmacological assessment of AGEN1884, a novel human IgG1 anti-CTLA-4 antibody
RB Gombos, A Gonzalez, M Manrique, D Chand, D Savitsky, B Morin, ...
PLoS One 13 (4), e0191926, 2018
212018
Role of the NF-κB transcription factor c-Rel in the generation of CD8+ T-cell responses to Toxoplasma gondii
KA Jordan, CD Dupont, ED Tait, HC Liou, CA Hunter
International immunology 22 (11), 851-861, 2010
162010
Two Vaccines for Staphylococcus aureus Induce a B-Cell-Mediated Immune Response
CD Dupont, IL Scully, RM Zimnisky, B Monian, CP Rossitto, EB O'Connell, ...
MSphere 3 (4), 10.1128/msphere. 00217-18, 2018
152018
Flt3 ligand is essential for survival and protective immune responses during toxoplasmosis
CD Dupont, G Harms Pritchard, S Hidano, DA Christian, S Wagage, ...
The Journal of Immunology 195 (9), 4369-4377, 2015
152015
Longitudinal multiparameter single-cell analysis of macaques immunized with pneumococcal protein-conjugated or unconjugated polysaccharide vaccines reveals distinct antigen …
B Jia, LK McNeil, CD Dupont, K Tsioris, RM Barry, IL Scully, AO Ogunniyi, ...
PLoS One 12 (9), e0183738, 2017
132017
Guanylate-binding proteins: niche recruiters for antimicrobial effectors
CD Dupont, CA Hunter
Immunity 37 (2), 191-193, 2012
132012
Phase I/II, open-label, multiple ascending dose trial of AGEN2034, an anti–PD-1 monoclonal antibody, in advanced solid malignancies: results of dose escalation in advanced …
C Drescher, KN Moore, JF Liu, DM O’Malley, EW Wang, JSZ Wang, ...
Annals of Oncology 29, viii412-viii413, 2018
92018
Evaluation of peripheral T cell subset proliferation as a pharmacodynamic assay to guide the development of anti-CTLA-4 and PD-1 antibody combinations in patients with solid tumors
P De Souza, A Malczewski, I Proscurshim, G Yuan, E Coart, C Dupont, ...
CANCER RESEARCH 78 (13), 2018
62018
Phase 1/2 open-label, multiple ascending dose trial of AGEN2034, an anti-PD-1 monoclonal antibody, in advanced solid malignancies: Results of dose escalation.
KN Moore, C Dresher, J Liu, DM O'Malley, EW Wang, JSZ Wang, ...
Journal of Clinical Oncology 36 (15_suppl), 3086-3086, 2018
62018
511 Initial results of a phase 1 study of intratumoral ONCR-177, an oncolytic herpes-simplex virus-1 expressing five immunomodulatory transgenes, in subjects with advanced …
JC Park, H Soliman, G Falchook, T Owonikoko, A Spreafico, E Massarelli, ...
Journal for ImmunoTherapy of Cancer 9 (Suppl 2), 2021
52021
Phase I/II study of CTLA-4 inhibitor AGEN1884+ PD-1 Inhibitor AGEN2034 in patients with advanced/refractory solid tumors, with expansion into 2L cervical cancer and solid tumors
J Coward, C Lemech, T Meniawy, CD Dupont, AM Gonzalez, M Lim, ...
Annals of Oncology 29, viii417, 2018
32018
Detection and characterization of fibrin/amyloid microclots in patients with post-acute sequelae of Covid-19
M Walker, EM Federico, DB Kell, C Dupont, A Proal, E Pretorius
Circulation 146 (Suppl_1), A15637-A15637, 2022
22022
Abstract CT104: Evaluation of peripheral T cell subset proliferation as a pharmacodynamic assay to guide the development of anti-CTLA-4 and PD-1 antibody combinations in …
PD Souza, A Malczewski, I Proscurshim, G Yuan, E Coart, C Dupont, ...
Cancer Research 78 (13_Supplement), CT104-CT104, 2018
22018
Phase I open-label, ascending dose trial of AGEN1884, an anti-CTLA-4 monoclonal antibody, in advanced solid malignancies: Dose selection for combination with PD-1 blockade.
BA Wilky, P Kumthekar, R Wesolowski, JJ Hwang, SI Park, I Proscurshim, ...
Journal of Clinical Oncology 36 (15_suppl), 3075-3075, 2018
22018
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