| Thioredoxin reductase and its inhibitors F Saccoccia, F Angelucci, G Boumis, D Carotti, G Desiato, A E Miele, ... Current Protein and Peptide Science 15 (6), 621-646, 2014 | 147 | 2014 |
| Crystal structure of the peroxisome proliferator-activated receptor γ (PPARγ) ligand binding domain complexed with a novel partial agonist: a new region of the hydrophobic … R Montanari, F Saccoccia, E Scotti, M Crestani, C Godio, F Gilardi, ... Journal of medicinal chemistry 51 (24), 7768-7776, 2008 | 126 | 2008 |
| Moonlighting by different stressors: crystal structure of the chaperone species of a 2-Cys peroxiredoxin F Saccoccia, P Di Micco, G Boumis, M Brunori, I Koutris, AE Miele, ... Structure 20 (3), 429-439, 2012 | 124 | 2012 |
| Mapping the catalytic cycle of Schistosoma mansoni thioredoxin glutathione reductase by X-ray crystallography F Angelucci, D Dimastrogiovanni, G Boumis, M Brunori, AE Miele, ... Journal of biological chemistry 285 (42), 32557-32567, 2010 | 81 | 2010 |
| Switching between the alternative structures and functions of a 2-Cys peroxiredoxin, by site-directed mutagenesis F Angelucci, F Saccoccia, M Ardini, G Boumis, M Brunori, L Di Leandro, ... Journal of molecular biology 425 (22), 4556-4568, 2013 | 64 | 2013 |
| On the mechanism and rate of gold incorporation into thiol-dependent flavoreductases F Saccoccia, F Angelucci, G Boumis, M Brunori, AE Miele, DL Williams, ... Journal of inorganic biochemistry 108, 105-111, 2012 | 46 | 2012 |
| Typical 2-Cys peroxiredoxins in human parasites: Several physiological roles for a potential chemotherapy target F Angelucci, AE Miele, M Ardini, G Boumis, F Saccoccia, A Bellelli Molecular and biochemical parasitology 206 (1-2), 2-12, 2016 | 35 | 2016 |
| Crystal structure of Plasmodium falciparum thioredoxin reductase, a validated drug target G Boumis, G Giardina, F Angelucci, A Bellelli, M Brunori, ... Biochemical and biophysical research communications 425 (4), 806-811, 2012 | 34 | 2012 |
| Investigating the antiparasitic potential of the marine sesquiterpene avarone, its reduced form avarol, and the novel semisynthetic thiazinoquinone analogue thiazoavarone C Imperatore, R Gimmelli, M Persico, M Casertano, A Guidi, F Saccoccia, ... Marine Drugs 18 (2), 112, 2020 | 33 | 2020 |
| Evolution of the p53-MDM2 pathway E Åberg, F Saccoccia, M Grabherr, WYJ Ore, P Jemth, G Hultqvist BMC Evolutionary Biology 17, 1-12, 2017 | 33 | 2017 |
| Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production A Guidi, C Lalli, R Gimmelli, E Nizi, M Andreini, N Gennari, F Saccoccia, ... PLoS Neglected Tropical Diseases 11 (10), e0005994, 2017 | 33 | 2017 |
| Harnessing the role of HDAC6 in idiopathic pulmonary fibrosis: design, synthesis, structural analysis, and biological evaluation of potent inhibitors G Campiani, C Cavella, JD Osko, M Brindisi, N Relitti, S Brogi, ... Journal of medicinal chemistry 64 (14), 9960-9988, 2021 | 30 | 2021 |
| Novel quinolone-based potent and selective HDAC6 inhibitors: Synthesis, molecular modeling studies and biological investigation N Relitti, AP Saraswati, G Chemi, M Brindisi, S Brogi, D Herp, ... European Journal of Medicinal Chemistry 212, 112998, 2021 | 30 | 2021 |
| Spiroindoline-capped selective HDAC6 inhibitors: design, synthesis, structural analysis, and biological evaluation AP Saraswati, N Relitti, M Brindisi, JD Osko, G Chemi, S Federico, A Grillo, ... ACS Medicinal Chemistry Letters 11 (11), 2268-2276, 2020 | 30 | 2020 |
| Screening and Phenotypical Characterization of Schistosoma mansoni Histone Deacetylase 8 (SmHDAC8) Inhibitors as Multistage Antischistosomal Agents F Saccoccia, M Brindisi, R Gimmelli, N Relitti, A Guidi, AP Saraswati, ... ACS Infectious Diseases 6 (1), 100-113, 2019 | 29 | 2019 |
| One ring (or two) to hold them all–on the structure and function of protein nanotubes F Angelucci, A Bellelli, M Ardini, R Ippoliti, F Saccoccia, V Morea The FEBS Journal 282 (15), 2827-2845, 2015 | 25 | 2015 |
| Identification of novel multi-stage histone deacetylase (HDAC) inhibitors that impair Schistosoma mansoni viability and egg production A Guidi, F Saccoccia, N Gennari, R Gimmelli, E Nizi, C Lalli, G Paonessa, ... Parasites & vectors 11, 1-10, 2018 | 22 | 2018 |
| Azetidin-2-one-based small molecules as dual hHDAC6/HDAC8 inhibitors: Investigation of their mechanism of action and impact of dual inhibition profile on cell viability S Federico, T Khan, A Fontana, S Brogi, R Benedetti, F Sarno, G Carullo, ... European Journal of Medicinal Chemistry 238, 114409, 2022 | 13 | 2022 |
| The crystal structure of archaeal serine hydroxymethyltransferase reveals idiosyncratic features likely required to withstand high temperatures F Angelucci, V Morea, S Angelaccio, F Saccoccia, R Contestabile, A Ilari Proteins: Structure, Function, and Bioinformatics 82 (12), 3437-3449, 2014 | 12 | 2014 |
| Thiazinoquinones as New Promising Multistage Schistosomicidal Compounds Impacting Schistosoma mansoni and Egg Viability R Gimmelli, M Persico, C Imperatore, F Saccoccia, A Guidi, M Casertano, ... ACS Infectious Diseases 6 (1), 124-137, 2019 | 9 | 2019 |
Andrea BellelliDirección de correo verificada de uniroma1.it
