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Yu Hsuan Lin, Ph.D.
Yu Hsuan Lin, Ph.D.
Scientist
Dirección de correo verificada de usc.edu
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O-GlcNAc modification blocks the aggregation and toxicity of the protein α-synuclein associated with Parkinson's disease
NP Marotta, YH Lin, YE Lewis, MR Ambroso, BW Zaro, MT Roth, ...
Nature chemistry 7 (11), 913-920, 2015
2772015
Site-specific differences in proteasome-dependent degradation of monoubiquitinated α-synuclein
T Abeywardana, YH Lin, R Rott, S Engelender, MR Pratt
Chemistry & biology 20 (10), 1207-1213, 2013
532013
Inhibiting the hexosamine biosynthetic pathway lowers O-GlcNAcylation levels and sensitizes cancer to environmental stress
LA Walter, YH Lin, CJ Halbrook, KN Chuh, L He, NJ Pedowitz, AR Batt, ...
Biochemistry 59 (34), 3169-3179, 2019
332019
Synthesis of a Bis-thio-acetone (BTA) Analogue of the Lysine Isopeptide Bond and its Application to Investigate the Effects of Ubiquitination and SUMOylation on α-Synuclein …
YE Lewis, T Abeywardana, YH Lin, A Galesic, MR Pratt
ACS chemical biology 11 (4), 931-942, 2016
322016
A Dual Small‐Molecule Rheostat for Precise Control of Protein Concentration in Mammalian Cells
YH Lin, MR Pratt
ChemBioChem 15 (6), 805-809, 2014
102014
O‑GlcNAc modification blocks the aggregation and toxicity of the protein α‑synuclein associated with Parkinson’s disease. Nat Chem. 2015; 7: 913–20
NP Marotta, YH Lin, YE Lewis, MR Ambroso, BW Zaro, MT Roth, ...
7
Probing hGFAT1 activity through small-molecule inhibition, CRISPR and Cryo-EM: Identifying the downstream effects of O-GlcNAc modified proteins and their role in cancer cell …
L Walter, YH Lin, K Chuh, F Nasertorabi, R Stevens, M Pratt
ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 253, 2017
2017
Using Chemical Biology Approaches to Investigate the Consequences of Protein Concentration and Activity in Cancer Cells
YH Lin
University of Southern California, 2016
2016
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Artículos 1–8