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Nick Kanaan
Nick Kanaan
Maibach Smiley Professor of Alzheimer's Research, Professor of Translational Neuroscience, Michigan
Verified email at msu.edu - Homepage
Title
Cited by
Cited by
Year
Tau kinetics in neurons and the human central nervous system
C Sato, NR Barthélemy, KG Mawuenyega, BW Patterson, BA Gordon, ...
Neuron 97 (6), 1284-1298. e7, 2018
5302018
Axonal transport defects in neurodegenerative diseases
GA Morfini, M Burns, LI Binder, NM Kanaan, N LaPointe, DA Bosco, ...
Journal of Neuroscience 29 (41), 12776-12786, 2009
5292009
Ageing as a primary risk factor for Parkinson's disease: evidence from studies of non-human primates
TJ Collier, NM Kanaan, JH Kordower
Nature Reviews Neuroscience 12 (6), 359-366, 2011
5142011
Intrastriatal injection of pre-formed mouse α-synuclein fibrils into rats triggers α-synuclein pathology and bilateral nigrostriatal degeneration
KL Paumier, KC Luk, FP Manfredsson, NM Kanaan, JW Lipton, TJ Collier, ...
Neurobiology of disease 82, 185-199, 2015
3922015
Characterization of prefibrillar Tau oligomers in vitro and in Alzheimer disease
KR Patterson, C Remmers, Y Fu, S Brooker, NM Kanaan, L Vana, S Ward, ...
Journal of Biological Chemistry 286 (26), 23063-23076, 2011
3722011
Pathogenic forms of tau inhibit kinesin-dependent axonal transport through a mechanism involving activation of axonal phosphotransferases
NM Kanaan, GA Morfini, NE LaPointe, GF Pigino, KR Patterson, Y Song, ...
Journal of Neuroscience 31 (27), 9858-9868, 2011
3152011
Tau oligomers and tau toxicity in neurodegenerative disease
SM Ward, DS Himmelstein, JK Lancia, LI Binder
Biochemical Society Transactions 40 (4), 667-671, 2012
2652012
Extracellular tau oligomers produce an immediate impairment of LTP and memory
M Fá, D Puzzo, R Piacentini, A Staniszewski, H Zhang, MA Baltrons, ...
Scientific reports 6 (1), 19393, 2016
2642016
Aging and Parkinson's disease: Different sides of the same coin?
TJ Collier, NM Kanaan, JH Kordower
Movement Disorders 32 (7), 983-990, 2017
2482017
Liquid-liquid phase separation induces pathogenic tau conformations in vitro
NM Kanaan, C Hamel, T Grabinski, B Combs
Nature communications 11 (1), 2809, 2020
2382020
Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo
DJ Apicco, PEA Ash, B Maziuk, C LeBlang, M Medalla, A Al Abdullatif, ...
Nature neuroscience 21 (1), 72-80, 2018
2172018
Axonal degeneration in Alzheimer's disease: when signaling abnormalities meet the axonal transport system
NM Kanaan, GF Pigino, ST Brady, O Lazarov, LI Binder, GA Morfini
Experimental neurology 246, 44-53, 2013
2152013
Lewy body-like alpha-synuclein inclusions trigger reactive microgliosis prior to nigral degeneration
MF Duffy, TJ Collier, JR Patterson, CJ Kemp, KC Luk, MG Tansey, ...
Journal of neuroinflammation 15, 1-18, 2018
1872018
Failure of proteasome inhibitor administration to provide a model of Parkinson's disease in rats and monkeys
JH Kordower, NM Kanaan, Y Chu, R Suresh Babu, J Stansell III, ...
Annals of Neurology: Official Journal of the American Neurological …, 2006
1662006
Heat shock protein 70 prevents both tau aggregation and the inhibitory effects of preexisting tau aggregates on fast axonal transport
KR Patterson, SM Ward, B Combs, K Voss, NM Kanaan, G Morfini, ...
Biochemistry 50 (47), 10300-10310, 2011
1262011
A method for combining RNAscope in situ hybridization with immunohistochemistry in thick free-floating brain sections and primary neuronal cultures
TM Grabinski, A Kneynsberg, FP Manfredsson, NM Kanaan
PloS one 10 (3), e0120120, 2015
1232015
Phosphorylation in the amino terminus of tau prevents inhibition of anterograde axonal transport
NM Kanaan, G Morfini, G Pigino, NE LaPointe, A Andreadis, Y Song, ...
Neurobiology of aging 33 (4), 826. e15-826. e30, 2012
1212012
Soluble pre-fibrillar tau and β-amyloid species emerge in early human Alzheimer’s disease and track disease progression and cognitive decline
DJ Koss, G Jones, A Cranston, H Gardner, NM Kanaan, B Platt
Acta neuropathologica 132, 875-895, 2016
1182016
Progression of tau pathology in cholinergic Basal forebrain neurons in mild cognitive impairment and Alzheimer's disease
L Vana, NM Kanaan, IC Ugwu, J Wuu, EJ Mufson, LI Binder
The American journal of pathology 179 (5), 2533-2550, 2011
1142011
Characterization of early pathological tau conformations and phosphorylation in chronic traumatic encephalopathy
NM Kanaan, K Cox, VE Alvarez, TD Stein, S Poncil, AC McKee
Journal of Neuropathology & Experimental Neurology 75 (1), 19-34, 2016
1062016
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