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Leah J Hogdal
Leah J Hogdal
Unknown affiliation
Verified email at fas.harvard.edu
Title
Cited by
Cited by
Year
Efficacy and biological correlates of response in a phase II study of venetoclax monotherapy in patients with acute myelogenous leukemia
M Konopleva, DA Pollyea, J Potluri, B Chyla, L Hogdal, T Busman, ...
Cancer discovery 6 (10), 1106-1117, 2016
10322016
Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia
R Pan, LJ Hogdal, JM Benito, D Bucci, L Han, G Borthakur, J Cortes, ...
Cancer discovery 4 (3), 362-375, 2014
7282014
A novel MCL1 inhibitor combined with venetoclax rescues venetoclax-resistant acute myelogenous leukemia
HE Ramsey, MA Fischer, T Lee, AE Gorska, MP Arrate, L Fuller, KL Boyd, ...
Cancer discovery 8 (12), 1566-1581, 2018
3072018
Blastic plasmacytoid dendritic cell neoplasm is dependent on BCL2 and sensitive to venetoclax
J Montero, J Stephansky, T Cai, GK Griffin, L Cabal-Hierro, K Togami, ...
Cancer discovery 7 (2), 156-164, 2017
2052017
Early changes in natural killer cell function indicate virologic response to interferon therapy for hepatitis C
G Ahlenstiel, B Edlich, LJ Hogdal, Y Rotman, M Noureddin, JJ Feld, ...
Gastroenterology 141 (4), 1231-1239. e2, 2011
1772011
MLL-rearranged acute lymphoblastic leukemias activate BCL-2 through H3K79 methylation and are sensitive to the BCL-2-specific antagonist ABT-199
JM Benito, L Godfrey, K Kojima, L Hogdal, M Wunderlich, H Geng, I Marzo, ...
Cell reports 13 (12), 2715-2727, 2015
1432015
Decreased mitochondrial priming determines chemoresistance of colon cancer stem cells
S Colak, CD Zimberlin, E Fessler, L Hogdal, PR Prasetyanti, CM Grandela, ...
Cell Death & Differentiation 21 (7), 1170-1177, 2014
1312014
Effect of ribavirin on viral kinetics and liver gene expression in chronic hepatitis C
Y Rotman, M Noureddin, JJ Feld, J Guedj, M Witthaus, H Han, YJ Park, ...
Gut 63 (1), 161-169, 2014
672014
Diminished apoptotic priming and ATM signalling confer a survival advantage onto aged haematopoietic stem cells in response to DNA damage
P Gutierrez-Martinez, L Hogdal, M Nagai, M Kruta, R Singh, K Sarosiek, ...
Nature Cell Biology 20 (4), 413-421, 2018
662018
Discovery and biological characterization of potent myeloid cell leukemia‐1 inhibitors
T Lee, Z Bian, B Zhao, LJ Hogdal, JL Sensintaffar, CM Goodwin, J Belmar, ...
FEBS letters 591 (1), 240-251, 2017
642017
Safety, efficacy, and patient-reported outcomes of venetoclax in combination with azacitidine for the treatment of patients with higher-risk myelodysplastic syndrome: a phaseá…
JS Garcia, AH Wei, U Borate, CY Fong, MR Baer, F Nolte, JG Jurcic, ...
Blood 136, 55-57, 2020
622020
Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia. Cancer Discov. 2014; 4: 362–375. doi: 10.1158/2159-8290
R Pan, LJ Hogdal, JM Benito, D Bucci, L Han, G Borthakur, J Cortes, ...
CD-13-0609.[Europe PMC free article][Abstract][CrossRef][Google Scholar], 0
59
Functionally identifiable apoptosis-insensitive subpopulations determine chemoresistance in acute myeloid leukemia
PD Bhola, BG Mar, RC Lindsley, JA Ryan, LJ Hogdal, TT Vo, ...
The Journal of clinical investigation 126 (10), 3827-3836, 2016
452016
Pevonedistat and azacitidine upregulate NOXA (PMAIP1) to increase sensitivity to venetoclax in preclinical models of acute myeloid leukemia
D Cojocari, BN Smith, JJ Purkal, MP Arrate, JD Huska, Y Xiao, A Gorska, ...
Haematologica 107 (4), 825, 2022
282022
Molecular responses are observed across mutational spectrum in treatment-na´ve higher-risk myelodysplastic syndrome patients treated with venetoclax plus azacitidine
JS Garcia, AH Wei, MA Jacoby, CY Fong, U Borate, MR Baer, ...
Blood 138, 241, 2021
252021
Overcoming mutational complexity in acute myeloid leukemia by inhibition of critical pathways
Y Saito, Y Mochizuki, I Ogahara, T Watanabe, L Hogdal, S Takagi, K Sato, ...
Science translational medicine 9 (413), eaao1214, 2017
232017
Venetoclax and azacitidine in the treatment of patients with relapsed/refractory myelodysplastic syndrome
AM Zeidan, U Borate, DA Pollyea, AM Brunner, F Roncolato, JS Garcia, ...
Blood 138, 537, 2021
182021
Hold on: females modulate sperm depletion from storage sites in the fly Drosophila melanogaster
MCB Qazi, L Hogdal
Journal of insect physiology 56 (9), 1332-1340, 2010
162010
Selective BCL-2 inhibition by ABT-199 causes on-target cell. death in acute myeloid leukemia. Cancer Discov. 2014; 4 (3): 362-75. doi: 10.1158/2159-8290
R Pan, LJ Hogdal, JM Benito, D Bucci, L Han, G Borthakur
CD-13-0609, 0
13
Selective BCL-2 inhibition by ABT-199 causes on-target cell death in acute myeloid leukemia. Cancer Discov. 2014; 4 (3): 362–75
R Pan, LJ Hogdal, JM Benito, D Bucci, L Han, G Borthakur
11
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