Chih-Chung Kuo
Chih-Chung Kuo
Other namesCurtis Kuo
Unknown affiliation
Verified email at
Cited by
Cited by
An enhanced CRISPR repressor for targeted mammalian gene regulation
NC Yeo, A Chavez, A Lance-Byrne, Y Chan, D Menn, D Milanova, ...
Nature methods 15 (8), 611-616, 2018
Combinatorial CRISPR–Cas9 screens for de novo mapping of genetic interactions
JP Shen, D Zhao, R Sasik, J Luebeck, A Birmingham, ...
Nature methods 14 (6), 573-576, 2017
The emerging role of systems biology for engineering protein production in CHO cells
CC Kuo, AWT Chiang, I Shamie, M Samoudi, JM Gutierrez, NE Lewis
Current Opinion in Biotechnology 51, 64-69, 2018
Increasing consensus of context-specific metabolic models by integrating data-inferred cell functions
A Richelle, AWT Chiang, CC Kuo, NE Lewis
PLoS computational biology 15 (4), e1006867, 2019
Modulating carbohydrate–protein interactions through glycoengineering of monoclonal antibodies to impact cancer physiology
AWT Chiang, S Li, PN Spahn, A Richelle, CC Kuo, M Samoudi, NE Lewis
Current opinion in structural biology 40, 104-111, 2016
Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteins
M Malm, CC Kuo, MM Barzadd, A Mebrahtu, N Wistbacka, R Razavi, ...
Metabolic engineering 72, 171-187, 2022
A unique esophageal extracellular matrix proteome alters normal fibroblast function in severe eosinophilic esophagitis
LY Hsieh, AWT Chiang, LD Duong, CC Kuo, SX Dong, R Dohil, R Kurten, ...
Journal of Allergy and Clinical Immunology 148 (2), 486-494, 2021
Restoration of DNA repair mitigates genome instability and increases productivity of Chinese hamster ovary cells
PN Spahn, X Zhang, Q Hu, H Lu, NK Hamaker, H Hefzi, S Li, CC Kuo, ...
Biotechnology and bioengineering 119 (3), 963-982, 2022
Combating viral contaminants in CHO cells by engineering innate immunity
AWT Chiang, S Li, BP Kellman, G Chattopadhyay, Y Zhang, CC Kuo, ...
Scientific reports 9 (1), 8827, 2019
The human secretome–the proteins secreted from human cells
M Uhlen, H Tegel, Sivertsson, CC Kuo, JM Gutierrez, NE Lewis, ...
BioRxiv, 465815, 2018
Increased mAb production in amplified CHO cell lines is associated with increased interaction of CREB1 with transgene promoter
H Dahodwala, P Kaushik, V Tejwani, CC Kuo, P Menard, M Henry, ...
Current research in biotechnology 1, 49-57, 2019
Dysregulation of the secretory pathway connects Alzheimer’s disease genetics to aggregate formation
CC Kuo, AWT Chiang, HM Baghdassarian, NE Lewis
Cell systems 12 (9), 873-884. e4, 2021
Systems glycobiology for discovering drug targets, biomarkers, and rational designs for glyco-immunotherapy
AWT Chiang, HM Baghdassarian, BP Kellman, B Bao, JT Sorrentino, ...
Journal of Biomedical Science 28, 1-15, 2021
From omics to cellular mechanisms in mammalian cell factory development
M Samoudi, HO Masson, CC Kuo, CM Robinson, NE Lewis
Current opinion in chemical engineering 32, 100688, 2021
In situ detection of protein interactions for recombinant therapeutic enzymes
M Samoudi, CC Kuo, CM Robinson, K Shams‐Ud‐Doha, SM Schinn, ...
Biotechnology and bioengineering 118 (2), 890-904, 2021
Combating viral contaminants in CHO cells by engineering STAT1 mediated innate immunity
AWT Chiang, S Li, BP Kellman, G Chattopadhyay, Y Zhang, CC Kuo, ...
bioRxiv, 423590, 2018
Deciphering the determinants of recombinant protein yield across the human secretome
HO Masson, CC Kuo, M Malm, M Lundqvist, Sievertsson, A Berling, ...
bioRxiv, 2022.12. 12.520152, 2022
Inferring secretory and metabolic pathway activity from omic data with secCellFie
HO Masson, M Samoudi, CM Robinson, CC Kuo, L Weiss, KSU Doha, ...
Metabolic Engineering 81, 273-285, 2024
Restoration of deficient DNA Repair Genes Mitigates Genome Instability and Increases Productivity of Chinese Hamster Ovary Cells
PN Spahn, X Zhang, Q Hu, NK Hamaker, H Hefzi, S Li, CC Kuo, Y Huang, ...
bioRxiv, 2021.01. 07.425558, 2021
A Novel Tissue-Free Method to Estimate Tumor-Derived Cell-Free DNA Quantity Using Tumor Methylation Patterns
CA Melton, P Freese, Y Zhou, A Shenoy, S Bagaria, C Chang, CC Kuo, ...
Cancers 16 (1), 82, 2023
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