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H. Isaac Chen
H. Isaac Chen
Dirección de correo verificada de uphs.upenn.edu
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A patient-derived glioblastoma organoid model and biobank recapitulates inter-and intra-tumoral heterogeneity
F Jacob, RD Salinas, DY Zhang, PTT Nguyen, JG Schnoll, SZH Wong, ...
Cell 180 (1), 188-204. e22, 2020
6402020
Sliced human cortical organoids for modeling distinct cortical layer formation
X Qian, Y Su, CD Adam, AU Deutschmann, SR Pather, EM Goldberg, ...
Cell Stem Cell 26 (5), 766-781. e9, 2020
3082020
Hemoglobin concentration and cerebral metabolism in patients with aneurysmal subarachnoid hemorrhage
M Oddo, A Milby, I Chen, S Frangos, E MacMurtrie, E Maloney-Wilensky, ...
Stroke 40 (4), 1275-1281, 2009
1482009
Detection of cerebral compromise with multimodality monitoring in patients with subarachnoid hemorrhage
HI Chen, MF Stiefel, M Oddo, AH Milby, E Maloney-Wilensky, S Frangos, ...
Neurosurgery 69 (1), 53-63, 2011
1372011
Molecular landscapes of human hippocampal immature neurons across lifespan
Y Zhou, Y Su, S Li, BC Kennedy, DY Zhang, AM Bond, Y Sun, F Jacob, ...
Nature 607 (7919), 527-533, 2022
1332022
Applications of human brain organoids to clinical problems
HI Chen, H Song, G Ming
Developmental Dynamics 248 (1), 53-64, 2019
1122019
Induced normothermia attenuates cerebral metabolic distress in patients with aneurysmal subarachnoid hemorrhage and refractory fever
M Oddo, S Frangos, A Milby, I Chen, E Maloney-Wilensky, EM Murtrie, ...
Stroke 40 (5), 1913-1916, 2009
1032009
Transplantation of Human Brain Organoids: Revisiting the Science and Ethics of Brain Chimeras
HI Chen, JA Wolf, R Blue, MM Song, JD Moreno, G Ming, H Song
Cell stem cell 25 (4), 462-472, 2019
902019
Development of and psychometric testing for the Brief Pain Inventory–Facial in patients with facial pain syndromes
JYK Lee, HI Chen, C Urban, A Hojat, E Church, SX Xie, JT Farrar
Journal of neurosurgery 113 (3), 516-523, 2010
822010
Barbiturate infusion for intractable intracranial hypertension and its effect on brain oxygenation
HI Chen, NR Malhotra, M Oddo, GG Heuer, JM Levine, PD LeRoux
Neurosurgery 63 (5), 880-887, 2008
822008
The measurement of pain in patients with trigeminal neuralgia
HI Chen, JY Lee
Clin Neurosurg 57, 129-133, 2010
812010
MXene-infused bioelectronic interfaces for multiscale electrophysiology and stimulation
N Driscoll, B Erickson, BB Murphy, AG Richardson, G Robbins, NV Apollo, ...
Science Translational Medicine 13 (612), eabf8629, 2021
792021
Role of monocyte chemoattractant protein‐1 (MCP‐1/CCL2) in migration of neural progenitor cells toward glial tumors
SN Magge, SZ Malik, NC Royo, HI Chen, LY Yu, EY Snyder, DM O'Rourke, ...
Journal of neuroscience research 87 (7), 1547-1555, 2009
792009
Primary cell culture of live neurosurgically resected aged adult human brain cells and single cell transcriptomics
JM Spaethling, YJ Na, J Lee, AV Ulyanova, GH Baltuch, TJ Bell, S Brem, ...
Cell reports 18 (3), 791-803, 2017
782017
Restoring nervous system structure and function using tissue engineered living scaffolds
LA Struzyna, JP Harris, KS Katiyar, HI Chen, DK Cullen
Neural regeneration research 10 (5), 679, 2015
782015
Acute lung injury is an independent risk factor for brain hypoxia after severe traumatic brain injury
M Oddo, E Nduom, S Frangos, L MacKenzie, I Chen, E Maloney-Wilensky, ...
Neurosurgery 67 (2), 338-344, 2010
742010
The evolution of neuroprosthetic interfaces
DO Adewole, MD Serruya, JP Harris, JC Burrell, D Petrov, HI Chen, ...
Critical Reviews™ in Biomedical Engineering 44 (1-2), 2016
702016
Rebuilding brain circuitry with living micro-tissue engineered neural networks
LA Struzyna, JA Wolf, CJ Mietus, DO Adewole, HI Chen, DH Smith, ...
Tissue Engineering Part A 21 (21-22), 2744-2756, 2015
682015
Tissue engineered nigrostriatal pathway for treatment of Parkinson's disease
LA Struzyna, KD Browne, ZD Brodnik, JC Burrell, JP Harris, HI Chen, ...
Journal of tissue engineering and regenerative medicine 12 (7), 1702-1716, 2018
672018
Transorbital endoscopic amygdalohippocampectomy: a feasibility investigation
HI Chen, LE Bohman, LA Loevner, TH Lucas
Journal of neurosurgery 120 (6), 1428-1436, 2014
632014
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Artículos 1–20