| Knocking down barriers: advances in siRNA delivery KA Whitehead, R Langer, DG Anderson Nature reviews Drug discovery 8 (2), 129-138, 2009 | 2834 | 2009 |
| Non-viral vectors for gene-based therapy H Yin, RL Kanasty, AA Eltoukhy, AJ Vegas, JR Dorkin, DG Anderson Nature Reviews Genetics 15 (8), 541-555, 2014 | 2035 | 2014 |
| Delivery materials for siRNA therapeutics R Kanasty, JR Dorkin, A Vegas, D Anderson Nature materials 12 (11), 967-977, 2013 | 1304 | 2013 |
| Subregion-and cell type–restricted gene knockout in mouse brain JZ Tsien, DF Chen, D Gerber, C Tom, EH Mercer, DJ Anderson, ... Cell 87 (7), 1317-1326, 1996 | 1251 | 1996 |
| CRISPR-Cas9 knockin mice for genome editing and cancer modeling RJ Platt, S Chen, Y Zhou, MJ Yim, L Swiech, HR Kempton, JE Dahlman, ... Cell 159 (2), 440-455, 2014 | 1142 | 2014 |
| A combinatorial library of lipid-like materials for delivery of RNAi therapeutics A Akinc, A Zumbuehl, M Goldberg, ES Leshchiner, V Busini, N Hossain, ... Nature biotechnology 26 (5), 561-569, 2008 | 1076 | 2008 |
| Treating metastatic cancer with nanotechnology A Schroeder, DA Heller, MM Winslow, JE Dahlman, GW Pratt, R Langer, ... Nature Reviews Cancer 12 (1), 39-50, 2012 | 962 | 2012 |
| Physical and mechanical properties of PLA, and their functions in widespread applications—A comprehensive review S Farah, DG Anderson, R Langer Advanced drug delivery reviews 107, 367-392, 2016 | 956 | 2016 |
| Genome editing with Cas9 in adult mice corrects a disease mutation and phenotype H Yin, W Xue, S Chen, RL Bogorad, E Benedetti, M Grompe, ... Nature biotechnology 32 (6), 551-553, 2014 | 917 | 2014 |
| Molecularly self-assembled nucleic acid nanoparticles for targeted in vivo siRNA delivery H Lee, AKR Lytton-Jean, Y Chen, KT Love, AI Park, ED Karagiannis, ... Nature nanotechnology 7 (6), 389-393, 2012 | 823 | 2012 |
| Nanoliter-scale synthesis of arrayed biomaterials and application to human embryonic stem cells DG Anderson, S Levenberg, R Langer Nature biotechnology 22 (7), 863-866, 2004 | 807 | 2004 |
| Lipid-like materials for low-dose, in vivo gene silencing KT Love, KP Mahon, CG Levins, KA Whitehead, W Querbes, JR Dorkin, ... Proceedings of the National Academy of Sciences 107 (5), 1864-1869, 2010 | 742 | 2010 |
| Therapeutic RNAi targeting PCSK9 acutely lowers plasma cholesterol in rodents and LDL cholesterol in nonhuman primates M Frank-Kamenetsky, A Grefhorst, NN Anderson, TS Racie, B Bramlage, ... Proceedings of the National Academy of Sciences 105 (33), 11915-11920, 2008 | 672 | 2008 |
| Rational development of LEA29Y (belatacept), a high‐affinity variant of CTLA4‐Ig with potent immunosuppressive properties CP Larsen, TC Pearson, AB Adams, P Tso, N Shirasugi, E StrobertM, ... American Journal of Transplantation 5 (3), 443-453, 2005 | 661 | 2005 |
| Therapeutic siRNA silencing in inflammatory monocytes in mice F Leuschner, P Dutta, R Gorbatov, TI Novobrantseva, JS Donahoe, ... Nature biotechnology 29 (11), 1005-1010, 2011 | 634 | 2011 |
| CRISPR-mediated direct mutation of cancer genes in the mouse liver W Xue, S Chen, H Yin, T Tammela, T Papagiannakopoulos, NS Joshi, ... Nature 514 (7522), 380-384, 2014 | 598 | 2014 |
| Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo H Yin, CQ Song, JR Dorkin, LJ Zhu, Y Li, Q Wu, A Park, J Yang, S Suresh, ... Nature biotechnology 34 (3), 328-333, 2016 | 581 | 2016 |
| Bio-inspired polymer composite actuator and generator driven by water gradients M Ma, L Guo, DG Anderson, R Langer Science 339 (6116), 186-189, 2013 | 554 | 2013 |
| Combinatorial development of biomaterials for clonal growth of human pluripotent stem cells Y Mei, K Saha, SR Bogatyrev, J Yang, AL Hook, ZI Kalcioglu, SW Cho, ... Nature materials 9 (9), 768-778, 2010 | 532 | 2010 |
| A combinatorial polymer library approach yields insight into nonviral gene delivery JJ Green, R Langer, DG Anderson Accounts of chemical research 41 (6), 749-759, 2008 | 525 | 2008 |
