Anti–PD-1/PD-L1 therapy of human cancer: past, present, and future L Chen, X Han The Journal of clinical investigation 125 (9), 3384-3391, 2015 | 1410 | 2015 |
Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy J Wang, J Sun, LN Liu, DB Flies, X Nie, M Toki, J Zhang, C Song, M Zarr, ... Nature medicine 25 (4), 656-666, 2019 | 504 | 2019 |
Coinhibitory receptor PD-1H preferentially suppresses CD4+ T cell–mediated immunity DB Flies, X Han, T Higuchi, L Zheng, J Sun, JJ Ye, L Chen The Journal of clinical investigation 124 (5), 1966-1975, 2014 | 274 | 2014 |
B7-H5 costimulates human T cells via CD28H Y Zhu, S Yao, BP Iliopoulou, X Han, MM Augustine, H Xu, RT Phennicie, ... Nature communications 4 (1), 1-12, 2013 | 186 | 2013 |
A Burned-Out CD8+ T-cell Subset Expands in the Tumor Microenvironment and Curbs Cancer Immunotherapy MF Sanmamed, X Nie, SS Desai, F Villaroel-Espindola, T Badri, D Zhao, ... Cancer discovery 11 (7), 1700-1715, 2021 | 95 | 2021 |
PD-1H (VISTA)–mediated suppression of autoimmunity in systemic and cutaneous lupus erythematosus X Han, MD Vesely, W Yang, MF Sanmamed, T Badri, J Alawa, ... Science translational medicine 11 (522), eaax1159, 2019 | 87 | 2019 |
Structural insight into T cell coinhibition by PD-1H (VISTA) BT Slater, X Han, L Chen, Y Xiong Proceedings of the National Academy of Sciences 117 (3), 1648-1657, 2020 | 38 | 2020 |
Targeting the CSF1/CSF1R axis is a potential treatment strategy for malignant meningiomas J Yeung, V Yaghoobi, D Miyagishima, MD Vesely, T Zhang, T Badri, ... Neuro-oncology 23 (11), 1922-1935, 2021 | 37 | 2021 |
Stimulating T cells against cancer with agonist immunostimulatory monoclonal antibodies X Han, MD Vesely International review of cell and molecular biology 342, 1-25, 2019 | 28 | 2019 |
YIV-906 potentiated anti-PD1 action against hepatocellular carcinoma by enhancing adaptive and innate immunity in the tumor microenvironment X Yang, W Lam, Z Jiang, F Guan, X Han, R Hu, W Cai, W Cheng, SH Liu, ... Scientific reports 11 (1), 13482, 2021 | 16 | 2021 |
PD-1H (VISTA) induces immune evasion in acute myeloid leukemia TK Kim, X Han, J Wang, M Sanmamed, T Zhang, S Halene, MM Pillai, ... Blood 130, 2658, 2017 | 12 | 2017 |
The CD8α–PILRα interaction maintains CD8+ T cell quiescence L Zheng, X Han, S Yao, Y Zhu, J Klement, S Wu, L Ji, G Zhu, X Cheng, ... Science 376 (6596), 996-1001, 2022 | 11 | 2022 |
YIV906 (PHY906) enhanced the antitumor activity of immune checkpoint blockade therapy: anti-PD1 against liver cancer W Lam, XC Yang, Z Jiang, X Han, F Guan, W Cheng, SH Liu, L Chen, ... Cancer Research 78 (13_Supplement), 2724-2724, 2018 | 4 | 2018 |
Development and characterization of monoclonal antibodies against mouse TSLP X Li, X Han, S Wang, Z Duan Hybridoma 29 (5), 425-430, 2010 | 3 | 2010 |
Programmed death-1 homolog (PD-1H/VISTA) blockade confers a synergistic anti-leukemia effect with PD-1 blockade TK Kim, X Han, Q Hu, C Hedgepath, J Hong, J Park, EF Mason, L Chen Blood 140 (Supplement 1), 87-88, 2022 | 2 | 2022 |
The development and functions of CD4+ T cells expressing a transgenic TCR specific for an MHC-I-restricted tumor antigenic epitope X Han, P Ye, L Luo, L Zheng, Y Liu, L Chen, S Wang Cellular & Molecular Immunology 8 (4), 333-340, 2011 | 2 | 2011 |
YIV-906 (PHY906) enhanced the anti-tumor activity of immune checkpoint blockade therapy (Anti-PD1) against liver cancer by changing the tumor micro-environment associated with … W Lam, X Yang, Z Jiang, X Han, F Guan, R Hu, CH Xu, W Cai, W Cheng, ... Cancer Research 79 (13_Supplement), 2252-2252, 2019 | 1 | 2019 |
The B7-CD28 paradigm revisited---a systemic receptor array approach (178.19) S Yao, Y Zhu, G Zhu, M Augustine, D Goode, J Wang, L Zheng, X Han, ... The Journal of Immunology 188 (1_Supplement), 178.19-178.19, 2012 | 1 | 2012 |
PD-1H/VISTA mediates immune evasion in acute myeloid leukemia TK Kim, X Han, Q Hu, EN Vandsemb, CM Fielder, J Hong, KW Kim, ... The Journal of clinical investigation 134 (3), 2024 | | 2024 |
Immune Inhibitory Molecule PD-1 Homolog (VISTA) Colocalizes with CD11b Myeloid Cells in Melanoma and Is Associated with Poor Outcomes MD Vesely, M Kidacki, P Gaule, S Gupta, NNN Chan, X Han, JT Yeung, ... Journal of Investigative Dermatology 144 (1), 106-115. e4, 2024 | | 2024 |