Proteomic mapping of the human mitochondrial intermembrane space in live cells via ratiometric APEX tagging V Hung, P Zou, HW Rhee, ND Udeshi, V Cracan, T Svinkina, SA Carr, ... Molecular cell 55 (2), 332-341, 2014 | 498 | 2014 |
Complementation of mitochondrial electron transport chain by manipulation of the NAD+/NADH ratio DV Titov, V Cracan, RP Goodman, J Peng, Z Grabarek, VK Mootha Science 352 (6282), 231-235, 2016 | 348 | 2016 |
IGF2BP2/IMP2-deficient mice resist obesity through enhanced translation of Ucp1 mRNA and other mRNAs encoding mitochondrial proteins N Dai, L Zhao, D Wrighting, D Krämer, A Majithia, Y Wang, V Cracan, ... Cell metabolism 21 (4), 609-621, 2015 | 164 | 2015 |
A genetically encoded tool for manipulation of NADP+/NADPH in living cells V Cracan, DV Titov, H Shen, Z Grabarek, VK Mootha Nature chemical biology 13 (10), 1088-1095, 2017 | 90 | 2017 |
Meclizine inhibits mitochondrial respiration through direct targeting of cytosolic phosphoethanolamine metabolism VM Gohil, L Zhu, CD Baker, V Cracan, A Yaseen, M Jain, CB Clish, ... Journal of Biological Chemistry 288 (49), 35387-35395, 2013 | 67 | 2013 |
IcmF is a fusion between the radical B12 enzyme isobutyryl-CoA mutase and its G-protein chaperone V Cracan, D Padovani, R Banerjee Journal of biological chemistry 285 (1), 655-666, 2010 | 39 | 2010 |
Visualization of a radical B12 enzyme with its G-protein chaperone M Jost, V Cracan, PA Hubbard, R Banerjee, CL Drennan Proceedings of the National Academy of Sciences 112 (8), 2419-2424, 2015 | 34 | 2015 |
Cobalt and corrinoid transport and biochemistry V Cracan, R Banerjee Metallomics and the Cell, 333-374, 2013 | 33 | 2013 |
Novel coenzyme B12-dependent interconversion of isovaleryl-CoA and pivalyl-CoA V Cracan, R Banerjee Journal of Biological Chemistry 287 (6), 3723-3732, 2012 | 28 | 2012 |
Downregulation of the tyrosine degradation pathway extends Drosophila lifespan AA Parkhitko, D Ramesh, L Wang, D Leshchiner, E Filine, R Binari, ... Elife 9, e58053, 2020 | 27 | 2020 |
Structural Basis for Substrate Specificity in Adenosylcobalamin-dependent Isobutyryl-CoA Mutase and Related Acyl-CoA Mutases*♦ M Jost, DA Born, V Cracan, R Banerjee, CL Drennan Journal of Biological Chemistry 290 (45), 26882-26898, 2015 | 27 | 2015 |
Novel B12-Dependent Acyl-CoA Mutases and Their Biotechnological Potential V Cracan, R Banerjee Biochemistry 51 (31), 6039-6046, 2012 | 26 | 2012 |
Engineered and native coenzyme B12-dependent isovaleryl-CoA/pivalyl-CoA mutase K Kitanishi, V Cracan, R Banerjee Journal of Biological Chemistry 290 (33), 20466-20476, 2015 | 13 | 2015 |
Cofactor Editing by the G-protein Metallochaperone Domain Regulates the Radical B12 Enzyme IcmF*♦ Z Li, K Kitanishi, UT Twahir, V Cracan, D Chapman, K Warncke, ... Journal of Biological Chemistry 292 (10), 3977-3987, 2017 | 8 | 2017 |
A genetically encoded tool to increase cellular NADH/NAD+ ratio in living cells X Pan, ML Heacock, EN Abdulaziz, S Violante, AL Zuckerman, ... Nature Chemical Biology, 1-11, 2023 | 6 | 2023 |
A natural fusion of flavodiiron, rubredoxin, and rubredoxin oxidoreductase domains is a self-sufficient water-forming oxidase of Trichomonas vaginalis EN Abdulaziz, TA Bell, B Rashid, ML Heacock, T Begic, OS Skinner, ... Journal of Biological Chemistry 298 (8), 2022 | 3 | 2022 |
Protein prostheses for mitochondrial diseases or conditions V Mootha, D Titov, V Cracan, Z Grabarek US Patent 11,866,736, 2024 | | 2024 |
ChREBP is activated by reductive stress and mediates GCKR-associated metabolic traits C Singh, B Jin, N Shrestha, AL Markhard, A Panda, SE Calvo, A Deik, ... Cell Metabolism 36 (1), 144-158. e7, 2024 | | 2024 |
UNRAVELING THE ROLE OF REDUCTIVE STRESS IN HEPATIC TRANSCRIPTIONAL REGULATION OF FATTY LIVER DISEASE B Jin, C Singh, GA Sola, V Cracan, RP Goodman HEPATOLOGY 78, S1668-S1668, 2023 | | 2023 |
A genetically encoded tool to increase cellular NADH/NAD+ ratio in living cells ML Heacock, EN Abdulaziz, X Pan, AL Zuckerman, S Violante, C Yao, ... bioRxiv, 2022.09. 20.508785, 2022 | | 2022 |