| ATRX loss promotes tumor growth and impairs nonhomologous end joining DNA repair in glioma C Koschmann, AA Calinescu, FJ Nunez, A Mackay, J Fazal-Salom, ... Science translational medicine 8 (328), 328ra28-328ra28, 2016 | 264 | 2016 |
| IDH1-R132H acts as a tumor suppressor in glioma via epigenetic up-regulation of the DNA damage response FJ Núñez, FM Mendez, P Kadiyala, MS Alghamri, MG Savelieff, ... Science translational medicine 11 (479), eaaq1427, 2019 | 209 | 2019 |
| Mechanisms of glioma formation: iterative perivascular glioma growth and invasion leads to tumor progression, VEGF-independent vascularization, and resistance to antiangiogenic … GJ Baker, VN Yadav, S Motsch, C Koschmann, AA Calinescu, Y Mineharu, ... Neoplasia 16 (7), 543-561, 2014 | 168 | 2014 |
| Integrated metabolic and epigenomic reprograming by H3K27M mutations in diffuse intrinsic pontine gliomas C Chung, SR Sweha, D Pratt, B Tamrazi, P Panwalkar, A Banda, J Bayliss, ... Cancer cell 38 (3), 334-349. e9, 2020 | 105 | 2020 |
| Recent advances and future of immunotherapy for glioblastoma N Kamran, A Calinescu, M Candolfi, M Chandran, Y Mineharu, AS Asad, ... Expert opinion on biological therapy 16 (10), 1245-1264, 2016 | 74 | 2016 |
| Molecular profiling and targeted therapy in pediatric gliomas: review and consensus recommendations Z Miklja, A Pasternak, S Stallard, T Nicolaides, C Kline-Nunnally, B Cole, ... Neuro-oncology 21 (8), 968-980, 2019 | 69 | 2019 |
| CSF H3F3A K27M circulating tumor DNA copy number quantifies tumor growth and in vitro treatment response S Stallard, MG Savelieff, K Wierzbicki, B Mullan, Z Miklja, A Bruzek, ... Acta neuropathologica communications 6, 1-4, 2018 | 67 | 2018 |
| Characterizing and targeting PDGFRA alterations in pediatric high-grade glioma C Koschmann, D Zamler, A MacKay, D Robinson, YM Wu, R Doherty, ... Oncotarget 7 (40), 65696, 2016 | 65 | 2016 |
| Survival after relapse of medulloblastoma C Koschmann, K Bloom, S Upadhyaya, JR Geyer, SES Leary Journal of pediatric hematology/oncology 38 (4), 269-273, 2016 | 65 | 2016 |
| ATRX mutations and glioblastoma: impaired DNA damage repair, alternative lengthening of telomeres, and genetic instability C Koschmann, PR Lowenstein, MG Castro Molecular & cellular oncology 3 (3), e1167158, 2016 | 62 | 2016 |
| Circumscribed/non-diffuse histology confers a better prognosis in H3K27M-mutant gliomas D Pratt, SK Natarajan, A Banda, C Giannini, P Vats, C Koschmann, ... Acta neuropathologica 135, 299-301, 2018 | 58 | 2018 |
| Everolimus improves the efficacy of dasatinib in PDGFRα-driven glioma Z Miklja, VN Yadav, RT Cartaxo, R Siada, CC Thomas, JR Cummings, ... The Journal of clinical investigation 130 (10), 5313-5325, 2020 | 57 | 2020 |
| The landscape of tumor cell states and spatial organization in H3-K27M mutant diffuse midline glioma across age and location I Liu, L Jiang, ER Samuelsson, S Marco Salas, A Beck, OA Hack, D Jeong, ... Nature Genetics 54 (12), 1881-1894, 2022 | 55 | 2022 |
| Mutated chromatin regulatory factors as tumor drivers in cancer C Koschmann, FJ Nunez, F Mendez, JA Brosnan-Cashman, AK Meeker, ... Cancer research 77 (2), 227-233, 2017 | 55 | 2017 |
| Survival benefit for individuals with constitutional mismatch repair deficiency undergoing surveillance C Durno, AB Ercan, V Bianchi, M Edwards, M Aronson, M Galati, ... Journal of Clinical Oncology 39 (25), 2779-2790, 2021 | 51 | 2021 |
| Adenoviral vector-mediated gene therapy for gliomas: coming of age MG Castro, M Candolfi, TJ Wilson, A Calinescu, C Paran, N Kamran, ... Expert opinion on biological therapy 14 (9), 1241-1257, 2014 | 50 | 2014 |
| Serial H3K27M cell-free tumor DNA (cf-tDNA) tracking predicts ONC201 treatment response and progression in diffuse midline glioma E Cantor, K Wierzbicki, RS Tarapore, K Ravi, C Thomas, R Cartaxo, ... Neuro-oncology 24 (8), 1366-1374, 2022 | 47 | 2022 |
| Imipridones affect tumor bioenergetics and promote cell lineage differentiation in diffuse midline gliomas JM Przystal, C Cianciolo Cosentino, S Yadavilli, J Zhang, S Laternser, ... Neuro-oncology 24 (9), 1438-1451, 2022 | 45 | 2022 |
| Targeting and therapeutic monitoring of H3K27M-mutant glioma K Wierzbicki, K Ravi, A Franson, A Bruzek, E Cantor, M Harris, MJ Homan, ... Current oncology reports 22, 1-9, 2020 | 45 | 2020 |
| Standardization of the liquid biopsy for pediatric diffuse midline glioma using ddPCR D Li, ER Bonner, K Wierzbicki, E Panditharatna, T Huang, R Lulla, ... Scientific reports 11 (1), 5098, 2021 | 43 | 2021 |
