Seguir
Mellinghoff Ingo
Mellinghoff Ingo
Dirección de correo verificada de mskcc.org
Título
Citado por
Citado por
Año
Tumor mutational load predicts survival after immunotherapy across multiple cancer types
RM Samstein, CH Lee, AN Shoushtari, MD Hellmann, R Shen, ...
Nature genetics 51 (2), 202-206, 2019
30992019
IDH mutation impairs histone demethylation and results in a block to cell differentiation
C Lu, PS Ward, GS Kapoor, D Rohle, S Turcan, O Abdel-Wahab, ...
Nature 483 (7390), 474-478, 2012
21472012
IDH1 mutation is sufficient to establish the glioma hypermethylator phenotype
S Turcan, D Rohle, A Goenka, LA Walsh, F Fang, E Yilmaz, C Campos, ...
Nature 483 (7390), 479-483, 2012
21172012
Molecular determinants of the response of glioblastomas to EGFR kinase inhibitors
IK Mellinghoff, MY Wang, I Vivanco, DA Haas-Kogan, S Zhu, EQ Dia, ...
New England Journal of Medicine 353 (19), 2012-2024, 2005
17242005
An inhibitor of mutant IDH1 delays growth and promotes differentiation of glioma cells
D Rohle, J Popovici-Muller, N Palaskas, S Turcan, C Grommes, ...
Science 340 (6132), 626-630, 2013
12692013
Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR
MS Neshat, IK Mellinghoff, C Tran, B Stiles, G Thomas, R Petersen, ...
Proceedings of the National Academy of Sciences 98 (18), 10314-10319, 2001
12372001
Assessing the significance of chromosomal aberrations in cancer: methodology and application to glioma
R Beroukhim, G Getz, L Nghiemphu, J Barretina, T Hsueh, D Linhart, ...
Proceedings of the National Academy of Sciences 104 (50), 20007-20012, 2007
12352007
High-throughput oncogene mutation profiling in human cancer
RK Thomas, AC Baker, RM DeBiasi, W Winckler, T LaFramboise, WM Lin, ...
Nature genetics 39 (3), 347-351, 2007
11632007
A brain tumor molecular imaging strategy using a new triple-modality MRI-photoacoustic-Raman nanoparticle
MF Kircher, A De La Zerda, JV Jokerst, CL Zavaleta, PJ Kempen, E Mittra, ...
Nature medicine 18 (5), 829-834, 2012
11542012
Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma
TF Cloughesy, AY Mochizuki, JR Orpilla, W Hugo, AH Lee, TB Davidson, ...
Nature medicine 25 (3), 477-486, 2019
11002019
Glioblastoma in adults: a Society for Neuro-Oncology (SNO) and European Society of Neuro-Oncology (EANO) consensus review on current management and future directions
PY Wen, M Weller, EQ Lee, BM Alexander, JS Barnholtz-Sloan, ...
Neuro-oncology 22 (8), 1073-1113, 2020
7112020
Hypoxia-inducible factor determines sensitivity to inhibitors of mTOR in kidney cancer
GV Thomas, C Tran, IK Mellinghoff, DS Welsbie, E Chan, B Fueger, ...
Nature medicine 12 (1), 122-127, 2006
6912006
Challenges to curing primary brain tumours
K Aldape, KM Brindle, L Chesler, R Chopra, A Gajjar, MR Gilbert, ...
Nature reviews Clinical oncology 16 (8), 509-520, 2019
6782019
Antitumor activity of rapamycin in a Phase I trial for patients with recurrent PTEN-deficient glioblastoma
TF Cloughesy, K Yoshimoto, P Nghiemphu, K Brown, J Dang, S Zhu, ...
PLoS medicine 5 (1), e8, 2008
6662008
Dual targeting of EGFR can overcome a major drug resistance mutation in mouse models of EGFR mutant lung cancer
L Regales, Y Gong, R Shen, E de Stanchina, I Vivanco, A Goel, ...
The Journal of clinical investigation 119 (10), 3000-3010, 2009
4762009
Tracking tumour evolution in glioma through liquid biopsies of cerebrospinal fluid
AM Miller, RH Shah, EI Pentsova, M Pourmaleki, S Briggs, N Distefano, ...
Nature 565 (7741), 654-658, 2019
4572019
An LXR agonist promotes glioblastoma cell death through inhibition of an EGFR/AKT/SREBP-1/LDLR–dependent pathway
D Guo, F Reinitz, M Youssef, C Hong, D Nathanson, D Akhavan, D Kuga, ...
Cancer discovery 1 (5), 442-456, 2011
4492011
Recurrent somatic mutation of FAT1 in multiple human cancers leads to aberrant Wnt activation
LGT Morris, AM Kaufman, Y Gong, D Ramaswami, LA Walsh, Ş Turcan, ...
Nature genetics 45 (3), 253-261, 2013
4352013
AKT activity determines sensitivity to mammalian target of rapamycin (mTOR) inhibitors by regulating cyclin D1 and c-myc expression
JF Gera, IK Mellinghoff, Y Shi, MB Rettig, C Tran, J Hsu, CL Sawyers, ...
Journal of Biological Chemistry 279 (4), 2737-2746, 2004
4292004
Somatic mutations of the Parkinson's disease–associated gene PARK2 in glioblastoma and other human malignancies
S Veeriah, BS Taylor, S Meng, F Fang, E Yilmaz, I Vivanco, ...
Nature genetics 42 (1), 77-82, 2010
4162010
El sistema no puede realizar la operación en estos momentos. Inténtalo de nuevo más tarde.
Artículos 1–20