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Aleidy Silva
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Individualizing liver transplant immunosuppression using a phenotypic personalized medicine platform
A Zarrinpar, DK Lee, A Silva, N Datta, T Kee, C Eriksen, K Weigle, ...
Science Translational Medicine 8 (333), 333ra49-333ra49, 2016
1382016
Mechanism-independent optimization of combinatorial nanodiamond and unmodified drug delivery using a phenotypically driven platform technology
H Wang, DK Lee, KY Chen, JY Chen, K Zhang, A Silva, CM Ho, D Ho
ACS nano 9 (3), 3332-3344, 2015
1232015
Optimizing drug combinations against multiple myeloma using a quadratic phenotypic optimization platform (QPOP)
MBMA Rashid, TB Toh, L Hooi, A Silva, Y Zhang, PF Tan, AL Teh, ...
Science translational medicine 10 (453), eaan0941, 2018
882018
Output-driven feedback system control platform optimizes combinatorial therapy of tuberculosis using a macrophage cell culture model
A Silva, BY Lee, DL Clemens, T Kee, X Ding, CM Ho, MA Horwitz
Proceedings of the national academy of sciences 113 (15), E2172-E2179, 2016
842016
Drug regimens identified and optimized by output-driven platform markedly reduce tuberculosis treatment time
BY Lee, DL Clemens, A Silva, BJ Dillon, S Masleša-Galić, S Nava, X Ding, ...
Nature communications 8 (1), 1-11, 2017
682017
Identification and optimization of combinatorial glucose metabolism inhibitors in hepatocellular carcinomas
MB Mohd Abdul Rashid, TB Toh, A Silva, L Nurrul Abdullah, CM Ho, D Ho, ...
Journal of laboratory automation 20 (4), 423-437, 2015
432015
Artificial intelligence enabled parabolic response surface platform identifies ultra-rapid near-universal TB drug treatment regimens comprising approved drugs
DL Clemens, BY Lee, A Silva, BJ Dillon, S Masleša-Galić, S Nava, X Ding, ...
PLOS ONE 14 (5), e0215607, 2019
312019
Multi-drug therapies for tuberculosis treatment
CM Ho, DL Clemens, BYL Clemens, MA Horwitz, AMS Vite, T Kee, ...
US Patent App. 10/080,749, 2018
22*2018
Ultra-rapid near universal TB drug regimen identified via parabolic response surface platform cures mice of both conventional and high susceptibility
BY Lee, DL Clemens, A Silva, BJ Dillon, S Masleša-Galić, S Nava, CM Ho, ...
PloS one 13 (11), e0207469, 2018
192018
When Medicine Meets Engineering—Paradigm Shifts in Diagnostics and Therapeutics
H Wang, A Silva, CM Ho
Diagnostics 3 (1), 126-154, 2013
72013
Phenotypic personalized medicine: adaptive optimization of patient-specific combination therapy
D Ho, CM Ho, A Zarrinpar, DK Lee, AMS Vite, N DATTA
US Patent App. 15/558,983, 2019
52019
Spatial redistribution of nano-particles using electrokinetic micro-focuser
DE Garcia, A Silva, CM Ho
Instrumentation, Metrology, and Standards for Nanomanufacturing 6648, 66480V, 2007
22007
Multi-drug therapies for tuberculosis treatment
CM Ho, DL Clemens, BYL Clemens, MA Horwitz, AMS Vite, T Kee, ...
US Patent 10,576,079, 2020
12020
Improved drug combinations for drug-resistant and drug-sensitive multiple myeloma
D Ho, CM Ho, AMS Vite, K Zhang, EKH CHOW, TB TOH, WJ CHNG, ...
US Patent App. 15/571,457, 2019
12019
Multi-drug therapies for tuberculosis treatment
CM Ho, DL Clemens, BYL Clemens, MA Horwitz, AMS Vite, T Kee, ...
US Patent 10,080,749, 2018
12018
Phenotypic Personalized Medicine: Mechanism-Independent Convergence Into Target Serum Tacrolimus Levels for Optimized Liver Transplant Immunosuppression
A Zarrinpar, A Silva, DK Lee, N Datta, CM Ho, D Ho
AMERICAN JOURNAL OF TRANSPLANTATION 15, 2015
12015
Globally optimizing therapeutic combinations against bortezomib-resistant multiple myeloma using a quantitative parabolic optimization platform
M Rashid, TB Toh, L Hooi, A Silva, Y Zhang, N Karnani, S Jha, CM Ho, ...
Cancer Research 78 (13 Supplement), 5818-5818, 2018
2018
1681PGlobally optimizing therapeutic combinations against bortezomib-resistant multiple myeloma using a quantitative parabolic optimization platform (QPOP)
M Rashid, TB Toh, NL Abdullah, A Silva, Y Zhang, PF Tan, AL Teh, ...
Annals of Oncology 28 (suppl_5), 2017
2017
Identification and optimization of combinatorial glucose metabolism inhibitors in hepatocellular carcinomas
MB Mohd Abdul Rashid, TB Toh, A Silva, L Nurrul Abdullah, CM Ho, D Ho, ...
Journal of laboratory automation 20 (4), 423-437, 2015
2015
Spatial redistribution of nano-particles using electrokinetic micro-focuser [6648-31]
DE Garcia, A Silva, C Ho
PROCEEDINGS-SPIE THE INTERNATIONAL SOCIETY FOR OPTICAL ENGINEERING 6648, 6648, 2007
2007
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