| Computational methods in drug discovery G Sliwoski, S Kothiwale, J Meiler, EW Lowe Jr Pharmacological reviews 66 (1), 334-395, 2014 | 2389 | 2014 |
| Jr Computational methods in drug discovery G Sliwoski, S Kothiwale, J Meiler, EW Lowe Jr Pharmacol Rev 66 (1), 334-395, 2014 | 104 | 2014 |
| Benchmarking ligand-based virtual High-Throughput Screening with the PubChem database M Butkiewicz, EW Lowe Jr, R Mueller, JL Mendenhall, PL Teixeira, ... Molecules 18 (1), 735-756, 2013 | 100 | 2013 |
| Discoidin domain receptor 1 (DDR1) kinase as target for structure-based drug discovery S Kothiwale, CM Borza, EW Lowe Jr, A Pozzi, J Meiler Drug discovery today 20 (2), 255-261, 2015 | 90 | 2015 |
| Cellular manganese content is developmentally regulated in human dopaminergic neurons KK Kumar, EW Lowe, Jr, AA Aboud, MD Neely, R Redha, JA Bauer, ... Scientific reports 4 (1), 6801, 2014 | 90 | 2014 |
| Reconstruction of SAXS profiles from protein structures DK Putnam, EW Lowe Jr, J Meiler Computational and structural biotechnology journal 8 (11), e201308006, 2013 | 62 | 2013 |
| High-throughput screening assay datasets from the pubchem database M Butkiewicz, Y Wang, SH Bryant, EW Lowe Jr, DC Weaver, J Meiler Chemical informatics (Wilmington, Del.) 3 (1), 1, 2017 | 37 | 2017 |
| Introduction to the BioChemical Library (BCL): An application-based open-source toolkit for integrated cheminformatics and machine learning in computer-aided drug discovery BP Brown, O Vu, AR Geanes, S Kothiwale, M Butkiewicz, EW Lowe Jr, ... Frontiers in pharmacology 13, 833099, 2022 | 26 | 2022 |
| Mechanistic studies of the tyrosinase-catalyzed oxidative cyclocondensation of 2-aminophenol to 2-aminophenoxazin-3-one C Washington, J Maxwell, J Stevenson, G Malone, EW Lowe Jr, Q Zhang, ... Archives of biochemistry and biophysics 577, 24-34, 2015 | 22 | 2015 |
| Evidence for substrate preorganization in the peptidylglycine α-amidating monooxygenase reaction describing the contribution of ground state structure to hydrogen tunneling NR McIntyre, EW Lowe Jr, JL Belof, M Ivkovic, J Shafer, B Space, ... Journal of the American Chemical Society 132 (46), 16393-16402, 2010 | 21 | 2010 |
| Thiorphan, tiopronin, and related analogs as substrates and inhibitors of peptidylglycine α-amidating monooxygenase (PAM) NR McIntyre, EW Lowe Jr, GH Chew, TC Owen, DJ Merkler FEBS letters 580 (2), 521-532, 2006 | 20 | 2006 |
| Substituted hippurates and hippurate analogs as substrates and inhibitors of peptidylglycine α-hydroxylating monooxygenase (PHM) DJ Merkler, AS Asser, LE Baumgart, N Carballo, SE Carpenter, GH Chew, ... Bioorganic & medicinal chemistry 16 (23), 10061-10074, 2008 | 19 | 2008 |
| BCL:: SAXS: GPU accelerated D ebye method for computation of small angle X‐ray scattering profiles DK Putnam, BE Weiner, N Woetzel, EW Lowe Jr, J Meiler Proteins: Structure, Function, and Bioinformatics 83 (8), 1500-1512, 2015 | 18 | 2015 |
| Imino-oxy acetic acid dealkylation as evidence for an inner-sphere alcohol intermediate in the reaction catalyzed by peptidylglycine α-hydroxylating monooxygenase NR McIntyre, EW Lowe Jr, DJ Merkler Journal of the American Chemical Society 131 (29), 10308-10319, 2009 | 17 | 2009 |
| Comparative analysis of machine learning techniques for the prediction of logP EW Lowe, M Butkiewicz, M Spellings, A Omlor, J Meiler 2011 IEEE Symposium on Computational Intelligence in Bioinformatics and …, 2011 | 13 | 2011 |
| BCL:: EMAS—enantioselective molecular asymmetry descriptor for 3D-QSAR G Sliwoski, EW Lowe Jr, M Butkiewicz, J Meiler Molecules 17 (8), 9971-9989, 2012 | 12 | 2012 |
| GPU-accelerated machine learning techniques enable QSAR modeling of large HTS data EW Lowe, M Butkiewicz, N Woetzel, J Meiler 2012 IEEE Symposium on Computational Intelligence in Bioinformatics and …, 2012 | 12 | 2012 |
| N-Acylethanolamines as novel alcohol dehydrogenase 3 substrates M Ivkovic, DR Dempsey, S Handa, JH Hilton, EW Lowe Jr, DJ Merkler Archives of biochemistry and biophysics 506 (2), 157-164, 2011 | 8 | 2011 |
| 3D-QSAR CoMFA study of benzoxazepine derivatives as mGluR5 positive allosteric modulators EW Lowe Jr, A Ferrebee, AL Rodriguez, PJ Conn, J Meiler Bioorganic & medicinal chemistry letters 20 (19), 5922-5924, 2010 | 8 | 2010 |
| Diet2Vec: Multi-scale analysis of massive dietary data W Tansey, EW Lowe Jr, JG Scott arXiv preprint arXiv:1612.00388, 2016 | 7 | 2016 |
