Aashiq H. Kachroo
Aashiq H. Kachroo
Associate Professor and Canada Research Chair in Systems & Synthetic Biology at Concordia University
Verified email at - Homepage
Cited by
Cited by
Systematic humanization of yeast genes reveals conserved functions and genetic modularity
AH Kachroo, JM Laurent, CM Yellman, AG Meyer, CO Wilke, EM Marcotte
Science 348 (6237), 921-925, 2015
Efforts to make and apply humanized yeast
JM Laurent, JH Young, AH Kachroo, EM Marcotte
Briefings in functional genomics 15 (2), 155-163, 2016
Single-step Precision Genome Editing in Yeast Using CRISPR-Cas9
A Akhmetov, JM Laurent, J Gollihar, EC Gardner, RK Garge, AD Ellington, ...
Bio-protocol 8 (6), 2018
An overview of tyrosine site‐specific recombination: from an Flp perspective
M Jayaram, CH Ma, AH Kachroo, PA Rowley, P Guga, HF Fan, ...
Mobile DNA III, 41-71, 2015
Humanization of yeast genes with multiple human orthologs reveals functional divergence between paralogs
JM Laurent, RK Garge, AI Teufel, CO Wilke, AH Kachroo, EM Marcotte
PLoS biology 18 (5), e3000627, 2020
Systematic bacterialization of yeast genes identifies a near-universally swappable pathway.
AH Kachroo, JM Laurent, A Akhmetov, M Szilagyi-Jones, CD McWhite, ...
eLife 6, 2017
Mutations that alter the regulation of the chb operon of Escherichia coli allow utilization of cellobiose
AH Kachroo, AK Kancherla, NS Singh, U Varshney, S Mahadevan
Molecular microbiology 66 (6), 1382-1395, 2007
Humanized yeast to model human biology, disease and evolution
AH Kachroo, M Vandeloo, BM Greco, M Abdullah
Disease models & mechanisms 15 (6), dmm049309, 2022
The many nuanced evolutionary consequences of duplicated genes
AI Teufel, MM Johnson, JM Laurent, AH Kachroo, EM Marcotte, CO Wilke
Molecular biology and evolution 36 (2), 304-314, 2019
The partitioning and copy number control systems of the selfish yeast plasmid: an optimized molecular design for stable persistence in host cells
YT Liu, S Sau, CH Ma, AH Kachroo, PA Rowley, KM Chang, HF Fan, ...
Microbiology spectrum 2 (5), 10.1128/microbiolspec. plas-0003-2013, 2014
Yeast cells expressing the human mitochondrial DNA polymerase reveal correlations between polymerase fidelity and human disease progression
Y Qian, AH Kachroo, CM Yellman, EM Marcotte, KA Johnson
Journal of Biological Chemistry 289 (9), 5970-5985, 2014
Systematic humanization of the yeast cytoskeleton discerns functionally replaceable from divergent human genes
RK Garge, JM Laurent, AH Kachroo, EM Marcotte
Genetics 215 (4), 1153-1169, 2020
Reactions of Cre with methylphosphonate DNA: similarities and contrasts with Flp and vaccinia topoisomerase
CH Ma, AH Kachroo, A Macieszak, TY Chen, P Guga, M Jayaram
PLoS One 4 (9), 2009
Metabolic engineering without plasmids
AH Kachroo, M Jayaram, PA Rowley
nature Biotechnology 27 (8), 729-731, 2009
Functional analysis of the genes encoding diaminopropionate ammonia lyase in Escherichia coli and Salmonella enterica serovar Typhimurium
JN Kalyani, N Ramachandra, AH Kachroo, S Mahadevan, HS Savithri
Journal of bacteriology 194 (20), 5604-5612, 2012
Electrostatic suppression allows tyrosine site-specific recombination in the absence of a conserved catalytic arginine
PA Rowley, AH Kachroo, CH Ma, AD Maciaszek, P Guga, M Jayaram
Journal of biological chemistry 285 (30), 22976-22985, 2010
Restoration of catalytic functions in Cre recombinase mutants by electrostatic compensation between active site and DNA substrate
AH Kachroo, CH Ma, PA Rowley, AD Maciaszek, P Guga, M Jayaram
Nucleic acids research 38 (19), 6589-6601, 2010
Humanization of yeast genes with multiple human orthologs reveals principles of functional divergence between paralogs
JM Laurent, RK Garge, AI Teufel, CO Wilke, AH Kachroo, EM Marcotte
bioRxiv, 668335, 2019
An overview of tyrosine site-specific recombination: from an Flp perspective. Microbiol Spectr. 3 (4), doi: 10.1128/microbiolspec
YV M Jayaram, CH Ma, AH Kachroo, PA Rowley, P Guga, HF Fan
Microbiology Spectrum, 2015
Hexapeptides that inhibit processing of branched DNA structures induce a dynamic ensemble of Holliday junction conformations
B Cannon, AH Kachroo, I Jarmoskaite, M Jayaram, R Russell
Journal of Biological Chemistry 290 (37), 22734-22746, 2015
The system can't perform the operation now. Try again later.
Articles 1–20