John Tainer

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Susan TsutakawaLawrence Berkeley National LaboratoryVerified email at lbl.gov
Michal HammelResearch Scientist, Lawrence Berkeley National LaboratoryVerified email at lbl.gov
Albino BacollaThe University of Texas MD Anderson Cancer CenterVerified email at mdanderson.org
Karl-Peter HopfnerLudwig-Maximilians-Universität MünchenVerified email at genzentrum.lmu.de
S P Lees-Miller, PhD, FRSCDepartment of Biochemistry & Molecular Biology, University of CalgaryVerified email at ucalgary.ca
Geir SlupphaugDepartment of Clinical and Molecular Medicine, Norwegian University of Science and Technology, NTNUVerified email at ntnu.no
R. Scott WilliamsNIH/NIEHSVerified email at niehs.nih.gov
David BarondeauProfessor Chemistry, Texas A&M UniversityVerified email at tamu.edu
Ivaylo IvanovProfessor of Chemistry, Georgia State UniversityVerified email at gsu.edu
Arthur OlsonProfesssor The Scripps Research InstituteVerified email at scripps.edu
Zu YeZhejiang Cancer Hospital, University of Chinese Academy of SciencesVerified email at zju.edu.cn
Jane S. RichardsonProfessor of Biochemistry, Duke UniversityVerified email at duke.edu
Seungil HanPfizer Inc.Verified email at pfizer.com
Michael N BoddyAssociate Professor, Scripps ResearchVerified email at scripps.edu
Andrej SaliUniversity of California, San FranciscoVerified email at salilab.org
Binghui ShenCity of HopeVerified email at coh.org
J. N. Mark GloverUniversity of AlbertaVerified email at ualberta.ca
Dina SchneidmanHebrew University of Jerusalem, IsraelVerified email at mail.huji.ac.il
Christopher M BrunsRetiredVerified email at esri.com
James HoltonUCSF/LBNL/SLACVerified email at lbl.gov

John Tainer

Director of Structural Biology, Professor at MD Anderson Cancer Center & Lawrence Berkeley Lab

Verified email at mdanderson.org - Homepage

Structural Molecular Biology Precision Oncology Cancer Bioinformatics DNA Replication DNA Damage


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Amyotrophic lateral Ssclerosis and structural defects in cu, Zn superoxide dismutase HX Deng, A Hentati, JA Tainer, Z Iqbal, A Cayabyab, WY Hung, ... Science 261 (5124), 1047-1051, 1993	1894	1993
X-ray solution scattering (SAXS) combined with crystallography and computation: defining accurate macromolecular structures, conformations and assemblies in solution CD Putnam, M Hammel, GL Hura, JA Tainer Quarterly reviews of biophysics 40 (3), 191-285, 2007	1471	2007
Determination and analysis of the 2 Å structure of copper, zinc superoxide dismutase JA Tainer, ED Getzoff, KM Beem, JS Richardson, DC Richardson Journal of molecular biology 160 (2), 181-217, 1982	1314	1982
Structure and mechanism of copper, zinc superoxide dismutase JA Tainer, ED Getzoff, JS Richardson, DC Richardson Nature 306 (5940), 284-287, 1983	1269	1983
Structural biology of Rad50 ATPase: ATP-driven conformational control in DNA double-strand break repair and the ABC-ATPase superfamily KP Hopfner, A Karcher, DS Shin, L Craig, LM Arthur, JP Carney, JA Tainer Cell 101 (7), 789-800, 2000	1210	2000
Type IV pilus structure and bacterial pathogenicity L Craig, ME Pique, JA Tainer Nature Reviews Microbiology 2 (5), 363-378, 2004	1016	2004
DNA-bound structures and mutants reveal abasic DNA binding by APE1 DNA repair and coordination CD Mol, T Izumi, S Mitra, JA Tainer Nature 403 (6768), 451-456, 2000	880	2000
Structure of nitric oxide synthase oxygenase dimer with pterin and substrate BR Crane, AS Arvai, DK Ghosh, C Wu, ED Getzoff, DJ Stuehr, JA Tainer Science 279 (5359), 2121-2126, 1998	877	1998
Accurate assessment of mass, models and resolution by small-angle scattering RP Rambo, JA Tainer Nature 496 (7446), 477-481, 2013	824	2013
PD-L1-mediated gasdermin C expression switches apoptosis to pyroptosis in cancer cells and facilitates tumour necrosis J Hou, R Zhao, W Xia, CW Chang, Y You, JM Hsu, L Nie, Y Chen, ... Nature Cell Biology, 1-12, 2020	745	2020
Robust, high-throughput solution structural analyses by small angle X-ray scattering (SAXS) GL Hura, AL Menon, M Hammel, RP Rambo, FL Poole Ii, SE Tsutakawa, ... Nature methods 6 (8), 606-612, 2009	742	2009
The structural biochemistry of the superoxide dismutases JJP Perry, DS Shin, ED Getzoff, JA Tainer Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1804 (2), 245-262, 2010	721	2010
The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair KP Hopfner, L Craig, G Moncalian, RA Zinkel, T Usui, BAL Owen, ... Nature 418 (6897), 562-566, 2002	718	2002
Electrostatic recognition between superoxide and copper, zinc superoxide dismutase ED Getzoff, JA Tainer, PK Weiner, PA Kollman, JS Richardson, ... Nature 306 (5940), 287-290, 1983	700	1983
Crystal structure of a monomeric retroviral protease solved by protein folding game players F Khatib, F DiMaio, Foldit Contenders Group, Foldit Void Crushers Group, ... Nature structural & molecular biology 18 (10), 1175-1177, 2011	692	2011
Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis JF Collawn, M Stangel, LA Kuhn, V Esekogwu, S Jing, IS Trowbridge, ... Cell 63 (5), 1061-1072, 1990	679	1990
A nucleotide-flipping mechanism from the structure of human uracil–DNA glycosylase bound to DNA G Slupphaug, CD Mol, B Kavli, AS Arvai, HE Krokan, JA Tainer Nature 384 (6604), 87-92, 1996	672	1996
DNA double-strand break repair pathway choice is directed by distinct MRE11 nuclease activities A Shibata, D Moiani, AS Arvai, J Perry, SM Harding, MM Genois, R Maity, ... Molecular cell 53 (1), 7-18, 2014	670	2014
Accurate SAXS profile computation and its assessment by contrast variation experiments D Schneidman-Duhovny, M Hammel, JA Tainer, A Sali Biophysical journal 105 (4), 962-974, 2013	637	2013
Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase KP Hopfner, A Karcher, L Craig, TT Woo, JP Carney, JA Tainer Cell 105 (4), 473-485, 2001	633	2001

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