Theodore Roth
Theodore Roth
Resident, Pathology, Stanford University
Verified email at
Cited by
Cited by
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing
DE Gordon, GM Jang, M Bouhaddou, J Xu, K Obernier, KM White, ...
Nature 583 (7816), 459-468, 2020
Microglia development and function
D Nayak, TL Roth, DB McGavern
Annual review of immunology 32, 367-402, 2014
Inflammation and neuroprotection in traumatic brain injury
KN Corps, TL Roth, DB McGavern
JAMA neurology 72 (3), 355-362, 2015
Reprogramming human T cell function and specificity with non-viral genome targeting
TL Roth, C Puig-Saus, R Yu, E Shifrut, J Carnevale, PJ Li, J Hiatt, J Saco, ...
Nature 559 (7714), 405-409, 2018
Comparative host-coronavirus protein interaction networks reveal pan-viral disease mechanisms
DE Gordon, J Hiatt, M Bouhaddou, VV Rezelj, S Ulferts, H Braberg, ...
Science 370 (6521), eabe9403, 2020
Transcranial amelioration of inflammation and cell death after brain injury
TL Roth, D Nayak, T Atanasijevic, AP Koretsky, LL Latour, DB McGavern
Nature 505 (7482), 223-228, 2014
Genome-wide CRISPR screens in primary human T cells reveal key regulators of immune function
E Shifrut, J Carnevale, V Tobin, TL Roth, JM Woo, CT Bui, PJ Li, ...
Cell 175 (7), 1958-1971. e15, 2018
Discovery of stimulation-responsive immune enhancers with CRISPR activation
DR Simeonov, BG Gowen, M Boontanrart, TL Roth, JD Gagnon, ...
Nature 549 (7670), 111-115, 2017
Polymer-stabilized Cas9 nanoparticles and modified repair templates increase genome editing efficiency
DN Nguyen, TL Roth, PJ Li, PA Chen, R Apathy, MR Mamedov, LT Vo, ...
Nature biotechnology 38 (1), 44-49, 2020
Pooled knockin targeting for genome engineering of cellular immunotherapies
TL Roth, PJ Li, F Blaeschke, JF Nies, R Apathy, C Mowery, R Yu, ...
Cell 181 (3), 728-744. e21, 2020
CRISPR screen in regulatory T cells reveals modulators of Foxp3
JT Cortez, E Montauti, E Shifrut, J Gatchalian, Y Zhang, O Shaked, Y Xu, ...
Nature 582 (7812), 416-420, 2020
Orthotopic replacement of T-cell receptor α-and β-chains with preservation of near-physiological T-cell function
K Schober, TR Müller, F Gökmen, S Grassmann, M Effenberger, ...
Nature biomedical engineering 3 (12), 974-984, 2019
CRISPR–Cas9 genome engineering of primary CD4+ T cells for the interrogation of HIV–host factor interactions
JF Hultquist, J Hiatt, K Schumann, MJ McGregor, TL Roth, P Haas, ...
Nature protocols 14 (1), 1-27, 2019
Large dataset enables prediction of repair after CRISPR–Cas9 editing in primary T cells
RT Leenay, A Aghazadeh, J Hiatt, D Tse, TL Roth, R Apathy, E Shifrut, ...
Nature biotechnology 37 (9), 1034-1037, 2019
High-yield genome engineering in primary cells using a hybrid ssDNA repair template and small-molecule cocktails
BR Shy, VS Vykunta, A Ha, A Talbot, TL Roth, DN Nguyen, WG Pfeifer, ...
Nature biotechnology 41 (4), 521-531, 2023
Single-molecule imaging of Hedgehog pathway protein Smoothened in primary cilia reveals binding events regulated by Patched1
L Milenkovic, LE Weiss, J Yoon, TL Roth, YRS Su, SJ Sahl, MP Scott, ...
Proceedings of the National Academy of Sciences 112 (27), 8320-8325, 2015
The CD28-transmembrane domain mediates chimeric antigen receptor heterodimerization with CD28
YD Muller, DP Nguyen, LMR Ferreira, P Ho, C Raffin, RVB Valencia, ...
Frontiers in immunology 12, 639818, 2021
XYZeq: Spatially resolved single-cell RNA sequencing reveals expression heterogeneity in the tumor microenvironment
Y Lee, D Bogdanoff, Y Wang, GC Hartoularos, JM Woo, CT Mowery, ...
Science advances 7 (17), eabg4755, 2021
RASA2 ablation in T cells boosts antigen sensitivity and long-term function
J Carnevale, E Shifrut, N Kale, WA Nyberg, F Blaeschke, YY Chen, Z Li, ...
Nature 609 (7925), 174-182, 2022
Migratory and adhesive cues controlling innate-like lymphocyte surveillance of the pathogen-exposed surface of the lymph node
Y Zhang, TL Roth, EE Gray, H Chen, LB Rodda, Y Liang, P Ventura, ...
Elife 5, e18156, 2016
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