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Avery D. Posey, Jr.
Avery D. Posey, Jr.
Dirección de correo verificada de pennmedicine.upenn.edu
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Distinct signaling of coreceptors regulates specific metabolism pathways and impacts memory development in CAR T cells
OU Kawalekar, RS O’Connor, JA Fraietta, L Guo, SE McGettigan, ...
Immunity 44 (2), 380-390, 2016
10792016
Engineered CAR T cells targeting the cancer-associated Tn-glycoform of the membrane mucin MUC1 control adenocarcinoma
AD Posey, RD Schwab, AC Boesteanu, C Steentoft, U Mandel, B Engels, ...
Immunity 44 (6), 1444-1454, 2016
5862016
Enhancing CAR T cell persistence through ICOS and 4-1BB costimulation
S Guedan, AD Posey Jr, C Shaw, A Wing, T Da, PR Patel, SE McGettigan, ...
JCI insight 3 (1), 2018
5062018
Rational development and characterization of humanized anti–EGFR variant III chimeric antigen receptor T cells for glioblastoma
LA Johnson, J Scholler, T Ohkuri, A Kosaka, PR Patel, SE McGettigan, ...
Science translational medicine 7 (275), 275ra22-275ra22, 2015
4922015
ICOS-based chimeric antigen receptors program bipolar TH17/TH1 cells
S Guedan, X Chen, A Madar, C Carpenito, SE McGettigan, MJ Frigault, ...
Blood, The Journal of the American Society of Hematology 124 (7), 1070-1080, 2014
4202014
Engineering and design of chimeric antigen receptors
S Guedan, H Calderon, AD Posey, MV Maus
Molecular Therapy-Methods & Clinical Development 12, 145-156, 2019
3972019
Safety and efficacy of intratumoral injections of chimeric antigen receptor (CAR) T cells in metastatic breast cancer
J Tchou, Y Zhao, BL Levine, PJ Zhang, MM Davis, JJ Melenhorst, ...
Cancer immunology research 5 (12), 1152-1161, 2017
3702017
Single-cell analyses identify brain mural cells expressing CD19 as potential off-tumor targets for CAR-T immunotherapies
KR Parker, D Migliorini, E Perkey, KE Yost, A Bhaduri, P Bagga, M Haris, ...
Cell 183 (1), 126-142. e17, 2020
3332020
Identification of chimeric antigen receptors that mediate constitutive or inducible proliferation of T cells
MJ Frigault, J Lee, MC Basil, C Carpenito, S Motohashi, J Scholler, ...
Cancer immunology research 3 (4), 356-367, 2015
3112015
Normal myoblast fusion requires myoferlin
KR Doherty, A Cave, DB Davis, AJ Delmonte, A Posey, JU Earley, ...
Oxford University Press for The Company of Biologists Limited 132 (24), 5565 …, 2005
2382005
Improving CART-cell therapy of solid tumors with oncolytic virus–driven production of a bispecific T-cell engager
A Wing, CA Fajardo, AD Posey Jr, C Shaw, T Da, RM Young, R Alemany, ...
Cancer immunology research 6 (5), 605-616, 2018
2342018
Expanding the therapeutic window for CAR T cell therapy in solid tumors: the knowns and unknowns of CAR T cell biology
K Watanabe, S Kuramitsu, AD Posey Jr, CH June
Frontiers in immunology 9, 2486, 2018
2062018
Checkpoint blockade reverses anergy in IL-13Rα2 humanized scFv-based CAR T cells to treat murine and canine gliomas
Y Yin, AC Boesteanu, ZA Binder, C Xu, RA Reid, JL Rodriguez, DR Cook, ...
Molecular Therapy-Oncolytics 11, 20-38, 2018
1482018
Single residue in CD28-costimulated CAR-T cells limits long-term persistence and antitumor durability
S Guedan, A Madar, V Casado-Medrano, C Shaw, A Wing, F Liu, ...
The Journal of clinical investigation 130 (6), 3087-3097, 2020
1302020
CAR T-cell therapies in glioblastoma: a first look
D Migliorini, PY Dietrich, R Stupp, GP Linette, AD Posey Jr, CH June
Clinical Cancer Research 24 (3), 535-540, 2018
1292018
The endocytic recycling protein EHD2 interacts with myoferlin to regulate myoblast fusion
KR Doherty, AR Demonbreun, GQ Wallace, A Cave, AD Posey, K Heretis, ...
Journal of Biological Chemistry 283 (29), 20252-20260, 2008
1272008
Glycan-directed CAR-T cells
C Steentoft, D Migliorini, TR King, U Mandel, CH June, AD Posey Jr
Glycobiology 28 (9), 656-669, 2018
902018
Driving cars to the clinic for solid tumors
M Castellarin, K Watanabe, CH June, CC Kloss, AD Posey Jr
Gene therapy 25 (3), 165-175, 2018
862018
Ferlin proteins in myoblast fusion and muscle growth
AD Posey Jr, A Demonbreun, EM McNally
Current topics in developmental biology 96, 203-230, 2011
732011
Endocytic recycling proteins EHD1 and EHD2 interact with fer-1-like-5 (Fer1L5) and mediate myoblast fusion
AD Posey, P Pytel, K Gardikiotes, AR Demonbreun, M Rainey, M George, ...
Journal of biological chemistry 286 (9), 7379-7388, 2011
712011
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