In vivo knock-down of multidrug resistance transporters ABCC1 and ABCC2 by AAV-delivered shRNAs and by artificial miRNAs F Borel, R van Logtenstein, A Koornneef, P Maczuga, T Ritsema, H Petry, ... Journal of RNAi and gene silencing: an international journal of RNA and gene …, 2011 | 74 | 2011 |
Apolipoprotein B knockdown by AAV-delivered shRNA lowers plasma cholesterol in mice A Koornneef, P Maczuga, R Van Logtenstein, F Borel, B Blits, T Ritsema, ... Molecular Therapy 19 (4), 731-740, 2011 | 60 | 2011 |
Mir‐142‐3p target sequences reduce transgene‐directed immunogenicity following intramuscular adeno‐associated virus 1 vector‐mediated gene delivery A Majowicz, P Maczuga, KL Kwikkers, S van der Marel, R van Logtenstein, ... The journal of gene medicine 15 (6-7), 219-232, 2013 | 57 | 2013 |
Embedding siRNA sequences targeting apolipoprotein B100 in shRNA and miRNA scaffolds results in differential processing and in vivo efficacy P Maczuga, J Lubelski, R Van Logtenstein, F Borel, B Blits, E Fakkert, ... Molecular Therapy 21 (1), 217-227, 2013 | 49 | 2013 |
Subunit-specific incorporation efficiency and kinetics in mitochondrial complex I homeostasis CEJ Dieteren, WJH Koopman, HG Swarts, JGP Peters, P Maczuga, ... Journal of Biological Chemistry 287 (50), 41851-41860, 2012 | 46 | 2012 |
Optimization and comparison of knockdown efficacy between polymerase II expressed shRNA and artificial miRNA targeting luciferase and Apolipoprotein B100 P Maczuga, A Koornneef, F Borel, H Petry, S van Deventer, T Ritsema, ... BMC biotechnology 12 (1), 1-12, 2012 | 38 | 2012 |
Therapeutic expression of hairpins targeting apolipoprotein B100 induces phenotypic and transcriptome changes in murine liver P Maczuga, J Verheij, C Van Der Loos, R Van Logtenstein, G Hooijer, ... Gene therapy 21 (1), 60-70, 2014 | 12 | 2014 |
Transcription factor Elk-1 participates in the interleukin-1β-dependent regulation of expression of immediate early response gene 3 (IER3) J Kochan, M Wawro, A Kolka, P Maczuga, A Kasza Cytokine 70 (2), 120-125, 2014 | 4 | 2014 |
Towards RNAi based therapy of liver diseases: diversity and complexity of shRNA and miRNA processing and functions P Maczuga Leiden University, 2013 | | 2013 |
Regulated miRNA expression as gene therapy of human diseases P Maczuga, A Koornneef, A Huseinovic, F Borel, S van Deventer, H Petry, ... HUMAN GENE THERAPY 22 (10), A49-A49, 2011 | | 2011 |
Apolipoprotein B100 knock-down by AAV-delivered shRNA lowers cholesterol in mice A Koornneef, P Maczuga, R van Logtenstein, F Borel, B Blits, T Ritsema, ... HUMAN GENE THERAPY 21 (10), 1393-1393, 2010 | | 2010 |
Regulated knockdown of Apolipoprotein B100 and Huntingtin by the GeneSwitch mifiprestone-inducible system P Maczuga, A Huseinovic, A Koornneef, S van Deventer, H Petry, ... Towards RNAi-based therapy of liver diseases, 175, 0 | | |
Mir-142-3p target sequences reduce transgene directed immunogenicity following intramuscular AAV1 vector-mediated gene delivery P Maczuga, KL Kwikkers, A Majowicz | | |
Therapeutic expression of hairpins targeting Apolipoprotein B100 induces differential changes in murine liver P Maczuga, J Verheij, C van der Loos, R van Logtenstein, G Hooijer, ... Towards RNAi-based therapy of liver diseases, 125, 0 | | |
Towards RNAi-based therapy of liver diseases P Maczuga | | |