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Valentin-Florian Rauca
Valentin-Florian Rauca
Lecturer, Babeș-Bolyai University, Centre for Systems Biology, Biodiversity and Bioresources ''3B''
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Anti-angiogenic and anti-inflammatory effects of long-circulating liposomes co-encapsulating curcumin and doxorubicin on C26 murine colon cancer cells
A Sesarman, L Tefas, B Sylvester, E Licarete, V Rauca, L Luput, L Patras, ...
Pharmacological reports 70 (2), 331-339, 2018
762018
Co-delivery of curcumin and doxorubicin in PEGylated liposomes favored the antineoplastic C26 murine colon carcinoma microenvironment
A Sesarman, L Tefas, B Sylvester, E Licarete, V Rauca, L Luput, L Patras, ...
Drug delivery and translational research 9, 260-272, 2019
652019
Trojan horse treatment based on PEG-coated extracellular vesicles to deliver doxorubicin to melanoma in vitro and in vivo
L Patras, AE Ionescu, C Munteanu, R Hajdu, A Kosa, A Porfire, E Licarete, ...
Cancer Biology & Therapy 23 (1), 1-16, 2022
272022
In vivo double targeting of C26 colon carcinoma cells and microenvironmental protumor processes using liposomal simvastatin
L Luput, E Licarete, DM Drotar, AL Nagy, A Sesarman, L Patras, ...
Journal of Cancer 9 (2), 440, 2018
262018
Biologically Active Ajuga Species Extracts Modulate Supportive Processes for Cancer Cell Development
VF Rauca, L Vlase, T Casian, A Sesarman, AM Gheldiu, A Mocan, ...
Frontiers in Pharmacology 10, 334, 2019
242019
A screening study for the development of simvastatin-doxorubicin liposomes, a co-formulation with future perspectives in colon cancer therapy
CI Barbălată, AS Porfire, A Sesarman, VF Rauca, M Banciu, D Muntean, ...
Pharmaceutics 13 (10), 1526, 2021
222021
Improved pharmacokinetics and reduced side effects of doxorubicin therapy by liposomal co-encapsulation with curcumin
A Sesarman, D Muntean, B Abrudan, L Tefas, B Sylvester, E Licarete, ...
Journal of Liposome Research 31 (1), 1-10, 2021
222021
Overcoming intrinsic doxorubicin resistance in melanoma by anti-angiogenic and anti-metastatic effects of liposomal prednisolone phosphate on tumor microenvironment
E Licarete, VF Rauca, L Luput, D Drotar, I Stejerean, L Patras, B Dume, ...
International journal of molecular sciences 21 (8), 2968, 2020
212020
Combination therapy of simvastatin and 5, 6-dimethylxanthenone-4-acetic acid synergistically suppresses the aggressiveness of B16. F10 melanoma cells
VF Rauca, E Licarete, L Luput, A Sesarman, L Patras, P Bulzu, ...
PLoS One 13 (8), e0202827, 2018
202018
HIF‑1α acts as a molecular target for simvastatin cytotoxicity in B16. F10 melanoma cells cultured under chemically induced hypoxia
E Licarete, A Sesarman, VF Rauca, L Luput, L Patras, M Banciu
Oncology letters 13 (5), 3942-3950, 2017
182017
Liposomal simvastatin sensitizes C26 murine colon carcinoma to the antitumor effects of liposomal 5‐fluorouracil in vivo
L Luput, A Sesarman, A Porfire, M Achim, D Muntean, T Casian, L Patras, ...
Cancer science 111 (4), 1344-1356, 2020
162020
Active tumor-targeting nano-formulations containing simvastatin and doxorubicin inhibit melanoma growth and angiogenesis
G Negrea, VF Rauca, MS Meszaros, L Patras, L Luput, E Licarete, ...
Frontiers in Pharmacology 13, 870347, 2022
122022
Remodeling tumor microenvironment by liposomal codelivery of DMXAA and simvastatin inhibits malignant melanoma progression
VF Rauca, L Patras, L Luput, E Licarete, VA Toma, A Porfire, AC Mot, ...
Scientific reports 11 (1), 22102, 2021
102021
The prednisolone phosphate‑induced suppression of the angiogenic function of tumor‑associated macrophages enhances the antitumor effects of doxorubicin on B16. F10 murine …
E Licarete, VF Rauca, L Luput, L Patras, A Sesarman, M Banciu
Oncology Reports 42 (6), 2694-2705, 2019
72019
S, tiufiuc
CI Barbălată, AS Porfire, A Sesarman, VF Rauca, M Banciu, D Muntean
R, 0
5
Targeting of M2 macrophages with IL-13-functionalized liposomal prednisolone inhibits melanoma angiogenesis in vivo
A Sesarman, L Luput, VF Rauca, L Patras, E Licarete, MS Meszaros, ...
Journal of Liposome Research, 1-12, 2024
2024
Development of a 3D Model for immunotherapy evaluation in melanoma.
MS Meszaros, GG Negrea, VA Toma, VF Rauca, E Licărete, L Pătraş, ...
Studia Universitatis Babes-Bolyai, Historia Artium 68 (2), 2023
2023
The use of functionalized liposomes and extracellular vesicles as drug delivery systems with high cancer-targeting efficacy.
VF Rauca, L Pătraş, G Negrea, E Licărete, A Porfire, L Barbu, L Luput, ...
Studia Universitatis Babes-Bolyai, Historia Artium 68 (2), 2023
2023
3D tumor spheroids as a model to unriddle the complexity of tumor microenvironment chemoresistance.
G Negrea, S Meszaros, S Drăgan, VA Toma, B Dume, VF Rauca, L Pătraş, ...
Studia Universitatis Babes-Bolyai, Historia Artium 68 (2), 2023
2023
487 Mast cells alter the invasive properties of melanoma cells in vitro
VF Rauca, CI Iuliano, K Mayer, S Kaesler, T Biedermann
Journal of Investigative Dermatology 142 (12), S264, 2022
2022
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